Gene_locus Report for: mycab-i9cu79

Mycobacterium abscessus Putative lipase/esterase

Comment

Other strains: Mycobacterium abscessus (5S-0921; 5S-1215; 5S-1212; 5S-0422; 5S-0304; 5S-0817; 5S-0421; 5S-0708; M94; 4S-0116-S; 4S-0726-RB; 4S-0303; 4S-0726-RA; 4S-0206; 4S-0116-R; subsp. bolletii (CCUG 48898 = JCM 1530050594; 1S-154-0310; 2B-0626; 1S-152-0914; 2B-0107; 2B-1231; 1S-153-0915; 2B-0912-S; 2B-0307; 2B-0912-R; 1S-151-0930); 6G-0728-S; ATCC 19977 / DSM 44196; 3A-0122-S; 6G-1108; 6G-0125-S; 3A-0930-S; 3A-0930-R; 3A-0810-R; 6G-0125-R; 3A-0731; 3A-0122-R; 3A-0119-R; 6G-0728-R; 6G-0212; M93; V06705; MAB_091912_2446; MAB_082312_2258; 47J26

Relationship

Family	\|	Est9X
Block	\|	H
Position in NCBI Life Tree	\|	Mycobacterium abscessus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Actinobacteria [phylum]: N E > Actinobacteria [class]: N E > Corynebacteriales: N E > Mycobacteriaceae: N E > Mycobacterium: N E > Mycobacterium chelonae group: N E > Mycobacterium abscessus subgroup: N E > Mycobacterium abscessus: N E

There are 71 a/b hydrolases in Mycobacterium abscessus view in a: Table

6_AlphaBeta_hydrolase : myca9-b1mau9Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative hydrolase, alpha/beta hydrolase fold, myca9-b1mcp9Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein, myca9-b1mcq3Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Alpha/beta hydrolase fold, myca9-b1meg6Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative hydrolase, myca9-b1men1Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative hydrolase, alpha/beta hydrolase fold, myca9-b1mg14Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein, myca9-b1mi42Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein.
A85-Est-Putative : myca9-b1max8Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein, myca9-b1mbb1Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein, myca9-b1mjf6Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein.
A85-Mycolyl-transferase : myca9-b1mel1Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Antigen 85-C, myca9-b1mel2Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Antigen 85-A, myca9-b1mel3Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Antigen 85-A/B/C, myca9-b1mm89Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein, myca9-b1mmv2Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Antigen 85-B.
Abhydrolase_9 : myca9-b1mhy2Mycobacterium abscessus; Mycobacterium abscessus subsp.; Mycobacterium chelonae, Putative uncharacterized protein, myca9-b1mmn3Mycobacterium abscessus;Mycobacterium abscessus subsp.; Mycobacterium chelonae, Putative uncharacterized protein, 9myco-a0a1m9k0v9Mycobacterium abscessus subsp. Transmembrane protein, 9myco-a0a1m9wpm8Mycobacterium abscessus subsp.; Mycobacterium mucogenicum Transmembrane protein.
Aclacinomycin-methylesterase_RdmC : myca9-b1mh71Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Probable lipase/esterase LipG, myca9-b1mh73Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Probable lipase/esterase LipG.
Carbon-carbon_bond_hydrolase : myca9-b1mge0Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative hydrolase, alpha/beta fold, myca9-b1mjt0Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative hydrolase, alpha/beta fold.
Carb_B_Bacteria : mycab-b1mch4Mycobacterium abscessus Mycobacterium massiliense; Mycobacterium immunogenum; Mycobacterium franklinii; Mycobacterium saopaulense Probable carboxylesterase (LipT), mycab-b1mdu3Mycobacterium abscessus, Mycobacterium massiliense, Mycobacterium chelonae, Probable carboxylesterase LipT, mycab-b1mes2Mycobacterium abscessus; Mycobacterium massiliense; Mycobacterium chelonae; Mycobacterium abscessus, Probable carboxylesterase LipT, mycab-b1mes3Mycobacterium abscessus, Mycobacterium massiliense, Mycobacterium chelonae Probable carboxylesterase LipT, mycab-b1mfj3Mycobacterium abscessus, Mycobacterium massiliense, Putative carboxylesterase, type B, mycab-b1mfk0Mycobacterium abscessus, Mycobacterium massiliense, Mycobacterium chelonae, Putative carboxylesterase, mycab-b1mgd3Mycobacterium abscessus; Mycobacterium massiliense; Mycobacterium chelonae Probable carboxylesterase, mycab-b1mkl9Mycobacterium abscessus, Mycobacterium massiliense, Mycobacterium chelonae, Probable carboxylesterase (LipT).
Chlorophyllase : 9myco-a0a0u0yp91Mycobacterium abscessus; Mycobacterium chelonae. Predicted dienelactone hydrolase, 9myco-a0a0u0ypy8Mycobacterium abscessus. Esterase, 9myco-a0a193jzs4Mycobacterium abscessus. Chlorophyllase.
DPP4N_Peptidase_S9 : myca9-b1mcm6Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Probable dipeptidyl peptidase IV.
Duf_1023 : myca9-b1mff2Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein, 9myco-a0a0u0y9q5Mycobacterium abscessus, Alpha/beta hydrolase of uncharacterised function (DUF1023), 9myco-a0a0u0ylc7Mycobacterium abscessus, Alpha/beta hydrolase of uncharacterised function (DUF1023), 9myco-a0a0u1bm89Mycobacterium abscessus, Alpha/beta hydrolase of uncharacterised function (DUF1023), 9myco-a0a193jvc9Mycobacterium abscessus, Uncharacterized protein.
Epoxide_hydrolase : myca9-b1mbf9Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative hydrolase, alpha/beta fold, myca9-b1mf26Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative hydrolase, alpha/beta fold, myca9-b1mfx1Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Possible epoxide hydrolase EphE, myca9-b1mg93Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Probable epoxide hydrolase EphA, myca9-b1mgu3Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Probable epoxide hydrolase EphA, myca9-b1mhl2Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Probable oxidoreductase EphD, myca9-b1mhv4Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Probable hydrolase, myca9-b1mku6Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Possible epoxide hydrolase EphF, myca9-b1mkz7Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Probable epoxide hydrolase EphC.
Fungal-Bact_LIP : myca9-b1mbj8Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein, myca9-b1mby5Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein, myca9-b1mdn9Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Probable lipase, myca9-b1mii6Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative lipase, myca9-b1mj56Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Possible triacylglycerol lipase, myca9-b1mja1Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative lipase, myca9-b1mjr6Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Secretory lipase family protein, myca9-b1mld0Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative lipase, myca9-b1mlq1Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein.
HOD-cofactorfree-dioxygenase : mycab-r4v1a9Mycobacterium abscessus, Mycobacterium chelonae,1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, mycab-x8en65

Mycobacterium abscessus, Mycobacterium chelonae, Putative dioxygenase (1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase).
Hormone-sensitive_lipase_like : mycab-Q8GNL0Mycobacterium abscessus, Mycobacterium sp., putative esterase/acetyl hydrolase.
Lipase_2 : myca9-b1mh82Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative triacylglycerol lipase, myca9-b1mhz7Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative triacylglycerol lipase.
MEST-like : myca9-b1mjl6Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative hydrolase, alpha/beta fold.
Monoglyceridelipase_lysophospholip : myca9-b1mdb6Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative uncharacterized protein.
NLS3-Tex30 : myca9-b1miq0Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Uncharacterized protein.
PE-PPE : myca9-b1mij3Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) PE/PPE family protein, mycab-a5a9u7Mycobacterium abscessus PE protein(and strain ATCC19977/DSM44196).
PHA_synth_III_C : myca9-b1mb08Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Possible long-chain acyl-CoA synthase, myca9-b1mcm4Mycobacterium abscessus (strain ATCC 19977 / DSM 44196) Putative hydrolase

Warning: This entry is a compilation of different species or line or strain with more than 90% amino acide identity. You can retrieve all strain data

Molecular evidence		Database
No mutation No structure No kinetic No Substrate No inhibitor		>3 Genbank links 43 more: AKUQ01000011, AKUD01000004, AKUC01000007 2 UniProt : B1MER7, R4UV22 2 UniProt : B1MER7, R4UV22 2 Interpro : B1MER7, R4UV22 2 Pfam : B1MER7, R4UV22 2 PIRSF : B1MER7, R4UV22 2 SUPERFAM : B1MER7, R4UV22

Sequence

Peptide

Graphical view for this peptide sequence: mycab-i9cu79
Colored MSA for Est9X (raw)
MPQHRRLTYGDHPSQYVDILEPDEPAAALVHVIHGGFWREALSAELTAPI ARDLCTDGFLVANIEYRRVGGGGGWPETFEDVKAAIAAVRQAEPDLVRSL AVGHSAGGHLSLLALAAGSADFAVALAPVSDVDRALRENLGDGAAAEFLG VAGSSPREVQTASPIGNLGHRRQHVLIHGLRDVNVPVEHSRHYVSAARAS GTPVDYFEFANLDHFDLIDPSSSAWYAAKQWIRYQLT
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA
MPQHRRLTYGDHPSQYVDILEPDEPAAALVHVIHGGFWREALSAELTAPI
ARDLCTDGFLVANIEYRRVGGGGGWPETFEDVKAAIAAVRQAEPDLVRSL
AVGHSAGGHLSLLALAAGSADFAVALAPVSDVDRALRENLGDGAAAEFLG
VAGSSPREVQTASPIGNLGHRRQHVLIHGLRDVNVPVEHSRHYVSAARAS
GTPVDYFEFANLDHFDLIDPSSSAWYAAKQWIRYQLT

References

2 more

Title:

Pang S, Renvoise A, Perret C, Guinier M, Chelghoum N, Brossier F, Capton E, Jarlier V, Sougakoff W

Ref:

PubMed

Title:

Choo SW, Wong YL, Yusoff AM, Leong ML, Wong GJ, Ong CS, Ng KP, Ngeow YF

Ref:

194

PubMed

Title:

Tettelin H, Sampaio EP, Daugherty SC, Hine E, Riley DR, Sadzewicz L, Sengamalay N, Shefchek K, Su Q and Zelazny AM <5 more author(s)>

Ref:

194

PubMed

Other Papers

Send your questions or comments to :Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.

For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page

webmaster

Acknowledgements and disclaimer