(3,5-dimethoxyphenyl)boronic-acid
IC50 FphE 0.54 +/- 0.03 microM
General
Type : Boron compound, Dimethoxyphenyl
Chemical_Nomenclature : (3,5-dimethoxyphenyl)boronic acid
Canonical SMILES : B(C1=CC(=CC(=C1)OC)OC)(O)O
InChI : InChI=1S\/C8H11BO4\/c1-12-7-3-6(9(10)11)4-8(5-7)13-2\/h3-5,10-11H,1-2H3
InChIKey : XUIURRYWQBBCCK-UHFFFAOYSA-N
Other name(s) : WS8 || 679-693-2 || 3,5-Dimethoxyphenylboronic acid || SCHEMBL8830 || 3,5-Dimethoxybenzeneboronic Acid || Compound Y43 || Compound W41
MW : 181.98
Formula : C8H11BO4
CAS_number : 192182-54-0
PubChem : 4374257
UniChem : XUIURRYWQBBCCK-UHFFFAOYSA-N
boronic-acid.gif)
Target
Families : (3,5-dimethoxyphenyl)boronic-acid ligand of proteins in family
6_AlphaBeta_hydrolase
Structure :
8UIX
Protein :
staau-SA2367
References (1)
| Title : Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation - Upadhyay_2025_Nat.Commun_16_5046 |
| Author(s) : Upadhyay T , Woods EC , Dela Ahator S , Julin K , Faucher FF , Uddin MJ , Hollander MJ , Pedowitz NJ , Abegg D , Hammond I , Eke IE , Wang S , Chen S , Bennett JM , Jo J , Lentz CS , Adibekian A , Fellner M , Bogyo M |
| Ref : Nat Commun , 16 :5046 , 2025 |
| Abstract : |
| PubMedSearch : Upadhyay_2025_Nat.Commun_16_5046 |
| PubMedID: 40447595 |
| Gene_locus related to this paper: staau-MW0741 , staau-SA2367 , staep-SE2095 |