| Title : Mixed Alkyl\/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets - Bennett_2024_bioRxiv__ |
| Author(s) : Bennett JM , Narwal SK , Kabeche S , Abegg D , Hackett F , Yeo T , Li VL , Muir RK , Faucher FF , Lovell S , Blackman MJ , Adibekian A , Yeh E , Fidock DA , Bogyo M |
| Ref : Biorxiv , : , 2024 |
| Abstract : |
| PubMedSearch : Bennett_2024_bioRxiv__ |
| PubMedID: 38260474 |
| Title : Mixed alkyl\/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets - Bennett_2024_Cell.Chem.Biol__ |
| Author(s) : Bennett JM , Narwal SK , Kabeche S , Abegg D , Thathy V , Hackett F , Yeo T , Li VL , Muir R , Faucher F , Lovell S , Blackman MJ , Adibekian A , Yeh E , Fidock DA , Bogyo M |
| Ref : Cell Chemical Biology , : , 2024 |
| Abstract : |
| PubMedSearch : Bennett_2024_Cell.Chem.Biol__ |
| PubMedID: 39137783 |
| Title : Chemoproteomics-Enabled De Novo Discovery of Photoswitchable Carboxylesterase Inhibitors for Optically Controlled Drug Metabolism - Dwyer_2021_Angew.Chem.Int.Ed.Engl_60_3071 |
| Author(s) : Dwyer BG , Wang C , Abegg D , Racioppo B , Qiu N , Zhao Z , Pechalrieu D , Shuster A , Hoch DG , Adibekian A |
| Ref : Angew Chem Int Ed Engl , 60 :3071 , 2021 |
| Abstract : |
| PubMedSearch : Dwyer_2021_Angew.Chem.Int.Ed.Engl_60_3071 |
| PubMedID: 33035395 |
| Title : Combined Omics Approach Identifies Gambogic Acid and Related Xanthones as Covalent Inhibitors of the Serine Palmitoyltransferase Complex - Hoch_2020_Cell.Chem.Biol_27_586 |
| Author(s) : Hoch DG , Abegg D , Hannich JT , Pechalrieu D , Shuster A , Dwyer BG , Wang C , Zhang X , You Q , Riezman H , Adibekian A |
| Ref : Cell Chemical Biology , 27 :586 , 2020 |
| Abstract : |
| PubMedSearch : Hoch_2020_Cell.Chem.Biol_27_586 |
| PubMedID: 32330443 |
| Title : Discovery and Evaluation of New Activity-Based Probes for Serine Hydrolases - Wang_2019_Chembiochem_20_2212 |
| Author(s) : Wang C , Abegg D , Dwyer BG , Adibekian A |
| Ref : Chembiochem , 20 :2212 , 2019 |
| Abstract : |
| PubMedSearch : Wang_2019_Chembiochem_20_2212 |
| PubMedID: 30968522 |
| Title : Cysteine-reactive probes and their use in chemical proteomics - Hoch_2018_Chem.Commun.(Camb)_54_4501 |
| Author(s) : Hoch DG , Abegg D , Adibekian A |
| Ref : Chem Commun (Camb) , 54 :4501 , 2018 |
| Abstract : |
| PubMedSearch : Hoch_2018_Chem.Commun.(Camb)_54_4501 |
| PubMedID: 29645055 |
| Title : Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation - Shimanaka_2017_Nat.Med_23_1287 |
| Author(s) : Shimanaka Y , Kono N , Taketomi Y , Arita M , Okayama Y , Tanaka Y , Nishito Y , Mochizuki T , Kusuhara H , Adibekian A , Cravatt BF , Murakami M , Arai H |
| Ref : Nat Med , 23 :1287 , 2017 |
| Abstract : |
| PubMedSearch : Shimanaka_2017_Nat.Med_23_1287 |
| PubMedID: 29035365 |
| Gene_locus related to this paper: human-PAFAH2 |
| Title : Mechanistic effects of protein palmitoylation and the cellular consequences thereof - Blaskovic_2014_Chem.Phys.Lipids_180_44 |
| Author(s) : Blaskovic S , Adibekian A , Blanc M , van der Goot GF |
| Ref : Chemistry & Physic of Lipids , 180 :44 , 2014 |
| Abstract : |
| PubMedSearch : Blaskovic_2014_Chem.Phys.Lipids_180_44 |
| PubMedID: 24534427 |
| Title : Diced electrophoresis gel assay for screening enzymes with specified activities - Komatsu_2013_J.Am.Chem.Soc_135_6002 |
| Author(s) : Komatsu T , Hanaoka K , Adibekian A , Yoshioka K , Terai T , Ueno T , Kawaguchi M , Cravatt BF , Nagano T |
| Ref : Journal of the American Chemical Society , 135 :6002 , 2013 |
| Abstract : |
| PubMedSearch : Komatsu_2013_J.Am.Chem.Soc_135_6002 |
| PubMedID: 23581642 |
| Title : Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2) - Adibekian_2013_Probe.Report__4 |
| Author(s) : Adibekian A , Martin BR , Chang JW , Hsu KL , Tsuboi K , Bachovchin DA , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2013 |
| Abstract : |
| PubMedSearch : Adibekian_2013_Probe.Report__4 |
| PubMedID: 24624468 |
| Gene_locus related to this paper: human-LYPLA2 |
| Title : Characterization of a serine hydrolase targeted by acyl-protein thioesterase inhibitors in Toxoplasma gondii - Kemp_2013_J.Biol.Chem_288_27002 |
| Author(s) : Kemp LE , Rusch M , Adibekian A , Bullen HE , Graindorge A , Freymond C , Rottmann M , Braun-Breton C , Baumeister S , Porfetye AT , Vetter IR , Hedberg C , Soldati-Favre D |
| Ref : Journal of Biological Chemistry , 288 :27002 , 2013 |
| Abstract : |
| PubMedSearch : Kemp_2013_J.Biol.Chem_288_27002 |
| PubMedID: 23913689 |
| Gene_locus related to this paper: toxgo-TgASH3 , toxgo-TgASH2 , toxgo-s8en43 , toxgo-s4ug63 , toxgo-a0a125yz56 |
| Title : Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 1 (LYPLA1) - Adibekian_2013_Probe.Report__3 |
| Author(s) : Adibekian A , Martin BR , Chang JW , Hsu KL , Tsuboi K , Bachovchin DA , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2013 |
| Abstract : |
| PubMedSearch : Adibekian_2013_Probe.Report__3 |
| PubMedID: 24624465 |
| Title : Global profiling of dynamic protein palmitoylation - Martin_2012_Nat.Methods_9_84 |
| Author(s) : Martin BR , Wang C , Adibekian A , Tully SE , Cravatt BF |
| Ref : Nat Methods , 9 :84 , 2012 |
| Abstract : |
| PubMedSearch : Martin_2012_Nat.Methods_9_84 |
| PubMedID: 22056678 |
| Title : Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes - Adibekian_2012_J.Am.Chem.Soc_134_10345 |
| Author(s) : Adibekian A , Martin BR , Chang JW , Hsu KL , Tsuboi K , Bachovchin DA , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Hodder PS , Rosen H , Cravatt BF |
| Ref : J Am Chem Soc , 134 :10345 , 2012 |
| Abstract : |
| PubMedSearch : Adibekian_2012_J.Am.Chem.Soc_134_10345 |
| PubMedID: 22690931 |
| Title : DAGLbeta inhibition perturbs a lipid network involved in macrophage inflammatory responses - Hsu_2012_Nat.Chem.Biol_8_999 |
| Author(s) : Hsu KL , Tsuboi K , Adibekian A , Pugh H , Masuda K , Cravatt BF |
| Ref : Nat Chemical Biology , 8 :999 , 2012 |
| Abstract : |
| PubMedSearch : Hsu_2012_Nat.Chem.Biol_8_999 |
| PubMedID: 23103940 |
| Gene_locus related to this paper: human-DAGLA , human-DAGLB |
| Title : Optimization and characterization of a triazole urea inhibitor for alpha\/beta hydrolase domain-containing protein 11 (ABHD11): anti-probe for LYPLA1\/LYPLA2 dual inhibitor ML211 - Adibekian_2011_Probe.Report__1 |
| Author(s) : Adibekian A , Hsu KL , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2011 |
| Abstract : |
| PubMedSearch : Adibekian_2011_Probe.Report__1 |
| PubMedID: 23658953 |
| Title : Optimization and characterization of a triazole urea dual inhibitor for lysophospholipase 1 (LYPLA1) and lysophospholipase 2 (LYPLA2) - Adibekian_2011_Probe.Report__5 |
| Author(s) : Adibekian A , Martin BR , Speers AE , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2011 |
| Abstract : |
| PubMedSearch : Adibekian_2011_Probe.Report__5 |
| PubMedID: 23658947 |
| Title : Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors - Adibekian_2011_Nat.Chem.Biol_7_469 |
| Author(s) : Adibekian A , Martin BR , Wang C , Hsu KL , Bachovchin DA , Niessen S , Hoover H , Cravatt BF |
| Ref : Nat Chemical Biology , 7 :469 , 2011 |
| Abstract : |
| PubMedSearch : Adibekian_2011_Nat.Chem.Biol_7_469 |
| PubMedID: 21572424 |
| Title : Optimization and characterization of a triazole urea inhibitor for platelet-activating factor acetylhydrolase type 2 (PAFAH2) - Adibekian_2011_Probe.Report__2 |
| Author(s) : Adibekian A , Hsu KL , Speers AE , Monillas ES , Brown SJ , Spicer T , Fernandez-Vega V , Ferguson J , Bahnson BJ , Cravatt BF , Hodder P , Rosen H |
| Ref : Probe Report , : , 2011 |
| Abstract : |
| PubMedSearch : Adibekian_2011_Probe.Report__2 |
| PubMedID: 23658960 |
| Title : Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening - Bachovchin_2010_Proc.Natl.Acad.Sci.U.S.A_107_20941 |
| Author(s) : Bachovchin DA , Ji T , Li W , Simon GM , Blankman JL , Adibekian A , Hoover H , Niessen S , Cravatt BF |
| Ref : Proc Natl Acad Sci U S A , 107 :20941 , 2010 |
| Abstract : |
| PubMedSearch : Bachovchin_2010_Proc.Natl.Acad.Sci.U.S.A_107_20941 |
| PubMedID: 21084632 |
| Title : Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases - Long_2010_J.Med.Chem_53_1830 |
| Author(s) : Long JZ , Jin X , Adibekian A , Li W , Cravatt BF |
| Ref : Journal of Medicinal Chemistry , 53 :1830 , 2010 |
| Abstract : |
| PubMedSearch : Long_2010_J.Med.Chem_53_1830 |
| PubMedID: 20099888 |