4,6-dialkoxyaurone-cpd8
Derivative of Aurone. Aurones are plant flavonoids that provide yellow color to the flowers of some popular ornamental plants. Antioxydant
General
Type : Flavonoid, Benzofuran, Lipase inhibitor
Chemical_Nomenclature : (2Z)-2-benzylidene-4,6-bis(10-hydroxydecoxy)-1-benzofuran-3-one
Canonical SMILES : C1=CC=C(C=C1)C=C2C(=O)C3=C(O2)C=C(C=C3OCCCCCCCCCCO)OCCCCCCCCCCO
InChI : InChI=1S\/C35H50O6\/c36-22-16-9-5-1-3-7-11-18-24-39-30-27-31(40-25-19-12-8-4-2-6-10-17-23-37)34-32(28-30)41-33(35(34)38)26-29-20-14-13-15-21-29\/h13-15,20-21,26-28,36-37H,1-12,16-19,22-25H2\/b33-26-
InChIKey : CPXGIOSKMJWGJT-MKFPQRGTSA-N
Other name(s) : Pancreatic lipase-IN-1, HY-157313, CS-0910388
MW : 566.8
Formula : C35H50O6
CAS_number :
PubChem : 169494226
UniChem : CPXGIOSKMJWGJT-MKFPQRGTSA-N
Target
Families : 4,6-dialkoxyaurone-cpd8 ligand of proteins in family
Pancreatic_lipase
Protein :
human-PNLIP
References (1)
| Title : Design, synthesis, biological evaluation and molecular docking of alkoxyaurones as potent pancreatic lipase inhibitors - Thi_2023_Bioorg.Med.Chem.Lett__129574 |
| Author(s) : Thi Vo CV , Thanh Nguyen T , Ngoc Dang T , Quoc Dao M , Thao Vo V , Thi Tran O , Thanh Vu L , Tran TD |
| Ref : Bioorganic & Medicinal Chemistry Lett , :129574 , 2023 |
| PubMedID: 38052378 |