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Antioxidant

General

Antioxidants are compounds that inhibit oxidation, a chemical reaction that can produce free radicals and chain reactions that may damage the cells of organisms. Ellements of multi target drugs that are designed for example to inhibit cholinesterases and limit free radicals produced in the brain of patients suffering of Alzheimer disease
Inhibitor Main targeted enzyme families Type Structure
CHEMBL3393736 Acridine Derivative of Tacrine Alkyl linked bis-ligand anti-Abeta-aggregation Multitarget Hydroxycinnamic-ester Antioxidant
Resveratrol-carbamate-cpd1 BCHE Carbamate Sulfure Compound Multitarget Antioxidant
Resveratrol-carbamate-cpd7 BCHE Carbamate Sulfur Compound Multitarget Antioxidant
MP30 BCHE Multitarget Derivative of Rivastigmine Carbamate Antioxidant Sulfur Compound
Silybin Pancreatic_lipase Natural Polyphenol Benzodioxin Antioxidant
CHEMBL5195416 ACHE Monoamine-oxidase-inhibitor Multitarget Piperidine Antioxidant
Ferulic-Acid-Piperazine-Cpd13a ACHE Multitarget Piperazin Quinoline Feruloyl Metal ion chelator anti-Abeta-aggregation Antioxidant
RIV-IND-5b2 ACHE Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Indole anti-Abeta-aggregation Antioxidant
AChE-HDAC-IN-1 ACHE BCHE Multitarget HDAC inhibitor Derivative of Tacrine anti-Abeta-aggregation Antioxidant
Morin Pancreatic_lipase Flavonoid Chromen Natural Antioxidant
Cannabidiol-amide-CB7 BCHE Cannabinoid-Receptor-ligand Multitarget Carbamate Antioxidant
Isosorbide-2-butylcarbamate-5-lipoic-acid-ester BCHE Isosorbide Carbamate Multitarget Antioxidant Sulfur Compound
4,6-dialkoxyaurone-cpd8 Pancreatic_lipase Flavonoid Benzofuran Lipase inhibitor Antioxidant
Dimethoxy-phenyl-pyrazino-indol-cpd5i ACHE Multitarget Indole Antioxidant
Tacrine-Sibiriline-Cpd7 BCHE ACHE Multitarget Acridine Derivative of Tacrine Alkyl linked bis-ligand Pyridine Carbamate Pyrrolidine Antioxidant
Di-tert-butyl-phenol-octylamino-acridine-17d ACHE Multitarget Acridine Derivative of Tacrine Antioxidant tert-Butyl Alkyl linked bis-ligand
Di-tert-butyl-phenol-octylamino-cycloheptaquinolin-18d BCHE Multitarget Derivative of Tacrine Quinoline Antioxidant tert-Butyl Alkyl linked bis-ligand
Diallyl-trisulfide ACHE Natural Sulfur Compound Antioxidant
Genistein-O-alkylbenzylamine-25d ACHE Multitarget Monoamine-oxidase-inhibitor anti-Abeta-aggregation Chromen Antioxidant
1d-phosphoryl-dihydroacridine BCHE ACHE Acridine Derivative of Tacrine Antioxidant anti-Abeta-aggregation
Melatonin-alkylbenzylamine-Cpd5 BCHE Antioxidant Derivative of Tryptamine Indole Multitarget Alkyl linked bis-ligand
Di-tert-butyl-4-Amino-2,3-cycloheptaquinoline-8c BCHE Quinoline Multitarget Antioxidant tert-Butyl
DFAH-12 BCHE ACHE Piperidine Hydroxycinnamic-ester Multitarget Antioxidant Derivative of Donepezil
TFAH-tacrine-ferulic-acid-hybrid-10n BCHE Multitarget Acrylate Antioxidant Derivative of Tacrine Hydroxycinnamic-ester Alkyl linked bis-ligand
Donepezil-idebenone-cpd9 BCHE Multitarget Antioxidant anti-Abeta-aggregation Derivative of Donepezil
Phenothiazine-Tacrine-1dC ACHE Phenothiazine Multitarget Derivative of Tacrine Antioxidant Acridine Alkyl linked bis-ligand anti-Abeta-aggregation Sulfur Compound
Cynaroside Lipoprotein_Lipase Glycoside Natural Flavonoid Chromen Antioxidant
Fluoropezil ACHE Multitarget Derivative of Donepezil Sulfur Compound Antioxidant Thiophen
2-tolylazo-1,3-aminoenketone-tacrine-7a ACHE Multitarget Derivative of Tacrine Alkyl linked bis-ligand Antioxidant
Salicylamide-8-Tacrine ACHE BCHE Multitarget Derivative of Tacrine Alkyl linked bis-ligand Antioxidant Salicylic
Citric-acid Polyesterase-lipase-cutinase Antioxidant
8U2-7AIX7AY-compound5i ACHE BCHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Triazol
8U5-7AIW-compound5g ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UE-7AIV-compound5f ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UQ-7AIU-compound5d ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UK-7AIT-compound5c ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UH-7AIS-compound5b ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
Berberine ACHE BCHE Natural Alkaloid Not AlphaBeta Hydrolase target Isoquinoline Benzodioxo Antioxidant
Tetracyclic-carbamate-ferulicacid-4a BCHE Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Feruloyl Antioxidant Alkyl linked bis-ligand
Pyranone-carbamate-cpd7p BCHE Carbamate Piperidine Antioxidant
6ZWE-Cpd3 BCHE ACHE Multitarget Antioxidant Benzodioxo Alkyl linked bis-ligand
Epigallocatechin-gallate Arylacetamide_deacetylase Derivative of Gallate Benzoate Natural Polyphenol Chromen Antioxidant
Melatonin Pectinacetylesterase-Notum Derivative of Tryptamine Indole Not AlphaBeta Hydrolase target Natural Antioxidant
Baicalein Carb_B_Chordata Natural Flavonoid Chromen Antioxidant
6F7Q-cpd11 BCHE Multitarget Antioxidant Piperidine Quinoline Metal ion chelator Inden Carboxamide
SCHEMBL8072716 Multitarget BACE1-inhibitor Derivative of Memoquin Antioxidant Alkyl linked bis-ligand Sulfur Compound
Memoquin ACHE Multitarget BACE1-inhibitor Derivative of Memoquin Antioxidant Alkyl linked bis-ligand
Lipocrine ACHE Multitarget Derivative of Tacrine Antioxidant Sulfur Compound Alkyl linked bis-ligand
Caffeic-acid FAE-Bacterial-promiscuous Hydroxycinnamic-ester Acrylate Antioxidant
Donepezil-8-Hydroxyquinoline-2b BCHE Quinoline Multitarget Antioxidant Derivative of Donepezil
Tacrine-Resveratrol-12 ACHE Multitarget Antioxidant Derivative of Tacrine
Tacrine-Trolox-7u ACHE Multitarget Antioxidant Derivative of Tacrine Carboxamide Alkyl linked bis-ligand Chromen
Donepezil-Melatonin-4u ACHE Derivative of Donepezil Derivative of Tryptamine Indole Alkyl linked bis-ligand Multitarget Antioxidant
Tacrine-Melatonin-Feruloyl-5c BCHE ACHE Derivative of Tacrine Derivative of Tryptamine Indole Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand
Methylene-blue ACHE BCHE Dye Drug Phenothiazine anti-tau-aggregation Multitarget Sulfur Compound Antioxidant
Chlorotacrine-juglone ACHE Multitarget Antioxidant Derivative of Tacrine Acridine Alkyl linked bis-ligand anti-Abeta-aggregation Naphthalen
AChE-IN-39 ACHE Antioxidant Benzofuran