Antioxidant

General

Antioxidants are compounds that inhibit oxidation, a chemical reaction that can produce free radicals and chain reactions that may damage the cells of organisms. Ellements of multi target drugs that are designed for example to inhibit cholinesterases and limit free radicals produced in the brain of patients suffering of Alzheimer disease

Inhibitor	Main targeted enzyme familyes	Type
Isosorbide-2-butylcarbamate-5-lipoic-acid-ester	BCHE	Isosorbide Carbamate Multitarget Antioxidant
Di-tert-butyl-phenol-octylamino-acridine-17d	ACHE	Multitarget Acridine Derivative of Tacrine Antioxidant tert-Butyl Alkyl linked bis-ligand
Di-tert-butyl-phenol-octylamino-cycloheptaquinolin-18d	BCHE	Multitarget Derivative of Tacrine Quinoline Antioxidant tert-Butyl Alkyl linked bis-ligand
Melatonin-alkylbenzylamine-Cpd5	BCHE	Antioxidant Derivative of Tryptamine Indole Multitarget Alkyl linked bis-ligand
Di-tert-butyl-4-Amino-2,3-cycloheptaquinoline-8c	BCHE	Quinoline Multitarget Antioxidant tert-Butyl
DFAH-12	BCHE ACHE	Piperidine Hydroxycinnamic-ester Multitarget Antioxidant Derivative of Donepezil
TFAH-tacrine-ferulic-acid-hybrid-10n	BCHE	Multitarget Acrylate Antioxidant Derivative of Tacrine Hydroxycinnamic-ester Alkyl linked bis-ligand
Donepezil-idebenone-cpd9	BCHE	Multitarget Antioxidant anti-Abeta-aggregation Derivative of Donepezil
Phenothiazine-Tacrine-1dC	ACHE	Phenothiazine Multitarget Derivative of Tacrine Antioxidant Acridine Alkyl linked bis-ligand anti-Abeta-aggregation Sulfur Compound
Fluoropezil	ACHE	Multitarget Derivative of Donepezil Sulfur Compound Antioxidant
Salicylamide-8-Tacrine	ACHE BCHE	Multitarget Derivative of Tacrine Alkyl linked bis-ligand Antioxidant Salicylic
8U2-7AIX7AY-compound5i	ACHE BCHE	Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8U5-7AIW-compound5g	ACHE	Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UE-7AIV-compound5f	ACHE	Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UQ-7AIU-compound5d	ACHE	Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UK-7AIT-compound5c	ACHE	Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
8UH-7AIS-compound5b	ACHE	Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant
Tetracyclic-carbamate-ferulicacid-4a	BCHE	Carbamate Natural_modified Derivative of Evodiamine Isoquinoline Quinazoline Feruloyl Antioxidant Alkyl linked bis-ligand
Pyranone-carbamate-cpd7p	BCHE	Carbamate Piperidine Antioxidant
6ZWE-Cpd3	BCHE ACHE	Multitarget Antioxidant Benzodioxo Alkyl linked bis-ligand
6F7Q-cpd11	BCHE	Multitarget Antioxidant Piperidine Quinoline Metal ion chelator Inden Carboxamide
Memoquin	ACHE	Multitarget BACE1-inhibitor Antioxidant Alkyl linked bis-ligand
Lipocrine	ACHE	Multitarget Derivative of Tacrine Antioxidant Sulfur Compound Alkyl linked bis-ligand
Donepezil-8-Hydroxyquinoline-2b	BCHE	Quinoline Multitarget Antioxidant Derivative of Donepezil
Tacrine-Resveratrol-12	ACHE	Multitarget Antioxidant Derivative of Tacrine
Tacrine-Trolox-7u	ACHE	Multitarget Antioxidant Derivative of Tacrine Carboxamide Alkyl linked bis-ligand
Donepezil-Melatonin-4u	ACHE	Derivative of Donepezil Derivative of Tryptamine Indole Alkyl linked bis-ligand Multitarget Antioxidant
Tacrine-Melatonin-Feruloyl-5c	BCHE	Derivative of Tacrine Derivative of Tryptamine Indole Multitarget Feruloyl Acrylate Antioxidant Hydroxycinnamic-ester Alkyl linked bis-ligand
Chlorotacrine-juglone	ACHE	Multitarget Antioxidant Derivative of Tacrine Acridine Alkyl linked bis-ligand anti-Abeta-aggregation Naphthalen