AChE-IN-27
AChE-IN-27 (compound 8c) AChE IC50=0.19 microM
General
Type : Coumarin, Cyanide, Chromen
Chemical_Nomenclature : 2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile
Canonical SMILES : CC1=CC=C(C=C1)C2C(=C(OC3=C2C(=O)OC4=CC=CC=C43)N)C#N
InChI : InChI=1S\/C20H14N2O3\/c1-11-6-8-12(9-7-11)16-14(10-21)19(22)25-18-13-4-2-3-5-15(13)24-20(23)17(16)18\/h2-9,16H,22H2,1H3
InChIKey : VRDLSXTUIVLTTD-UHFFFAOYSA-N
Other name(s) : HY-148108 || compound 8c
MW : 330.3
Formula : C20H14N2O3
CAS_number : 177028-90-9
PubChem : 2835002
UniChem : VRDLSXTUIVLTTD-UHFFFAOYSA-N
Target
Families : AChE-IN-27 ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Synthesis of new 3, 4-dihydropyrano [c] chromene derivatives and their evaluation as acetyl cholinesterase inhibitors - Bouazizi_2014_Eur.J.Chem_5_457 |
| Author(s) : Bouazizi Y , Romdhane A , Ben Jannet H |
| Ref : European Journal of Chemistry , 5 :457 , 2014 |
| Abstract : |
| PubMedSearch : Bouazizi_2014_Eur.J.Chem_5_457 |
| PubMedID: |