AChE-IN-57
AChE IC50 30nM
General
Type : Piperidine, Pyrimidine
Chemical_Nomenclature : 4-N-(4-chlorophenyl)-2-N-(2-piperidin-1-ylethyl)pyrimidine-2,4-diamine || N4-(4-chlorophenyl)-N2-(2-(piperidin-1-yl)ethyl)pyrimidine-2,4-diamine
Canonical SMILES : C1CCN(CC1)CCNC2=NC=CC(=N2)NC3=CC=C(C=C3)Cl
InChI : InChI=1S\/C17H22ClN5\/c18-14-4-6-15(7-5-14)21-16-8-9-19-17(22-16)20-10-13-23-11-2-1-3-12-23\/h4-9H,1-3,10-13H2,(H2,19,20,21,22)
InChIKey : VEGUFTMWVKJTLZ-UHFFFAOYSA-N
Other name(s) : HY-162258 || CS-0999105 || 5b || SP-2 || B-1
MW : 331.8
Formula : C17H22ClN5
CAS_number :
PubChem : 170836194
UniChem : VEGUFTMWVKJTLZ-UHFFFAOYSA-N
Target
Families : AChE-IN-57 ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Novel Substituted Pyrimidine Derivatives as Potential Anti-Alzheimer's Agents: Synthesis, Biological, and Molecular Docking Studies - Pant_2024_ACS.Chem.Neurosci__ |
| Author(s) : Pant S , Kumar KR , Rana P , Anthwal T , Ali SM , Gupta M , Chauhan M , Nain S |
| Ref : ACS Chem Neurosci , : , 2024 |
| Abstract : |
| PubMedSearch : Pant_2024_ACS.Chem.Neurosci__ |
| PubMedID: 38320262 |