Aldoxycarb
metabolite of aldicarb, metabolized at the sulphur atom via two sequential oxidations, first to the sulphoxide (aldicarb sulphoxide) and then to the sulphone || . Aldicarb-sulphone : L. cuprina AChE, IC50 [nM] 2666 +/- 240 ; Human AChE, IC50 [nM] >30,000
General
Type : Insecticide, Carbamate, Sulfur Compound
Chemical_Nomenclature : [(E)-(2-methyl-2-methylsulfonylpropylidene)amino] N-methylcarbamate
Canonical SMILES : CC(C)(C=NOC(=O)NC)S(=O)(=O)C
InChI : InChI=1S\/C7H14N2O4S\/c1-7(2,14(4,11)12)5-9-13-6(10)8-3\/h5H,1-4H3,(H,8,10)\/b9-5+
InChIKey : YRRKLBAKDXSTNC-WEVVVXLNSA-N
Other name(s) : Aldicarb-sulfone || Aldicarb sulfone || Sulfocarb || Standak || DTXSID6023862 || RefChem:915377 || DTXCID30809806 || [(2-methyl-2-methylsulfonylpropylidene)amino] N-methylcarbamate || Temik sulfone || Aldoxycarbe || Yangdimiewei || RefChem:110651 || SCHEMBL23560 || CHEMBL2138916 || CHEBI:82051
Target
Families : Aldoxycarb ligand of proteins in family
ACHE
References (2)
| Title : The characterization of Lucilia cuprina acetylcholinesterase as a drug target, and the identification of novel inhibitors by high throughput screening - Ilg_2011_Insect.Biochem.Mol.Biol_41_470 |
| Author(s) : Ilg T , Cramer J , Lutz J , Noack S , Schmitt H , Williams H , Newton T |
| Ref : Insect Biochemistry & Molecular Biology , 41 :470 , 2011 |
| Abstract : |
| PubMedSearch : Ilg_2011_Insect.Biochem.Mol.Biol_41_470 |
| PubMedID: 21530657 |
| Title : Simple determination of oxime carbamates in soil and environmental water by high pressure liquid chromatography - Dekker_1983_J.Environ.Sci.Health.[B]_18_379 |
| Author(s) : Dekker A , Houx NW |
| Ref : J Environ Sci Health [B] , 18 :379 , 1983 |
| Abstract : |
| PubMedSearch : Dekker_1983_J.Environ.Sci.Health.[B]_18_379 |
| PubMedID: 6875217 |