Alkynyl-cyanopyrrolidine-1
General
Type : Pyrrolidine, Cyanide, Alkyne
Chemical_Nomenclature : (2S)-2-amino-2-cyclopentyl-1-[(2R,5S)-2-ethynyl-5-methanimidoylpyrrolidin-1-yl]ethanone
Canonical SMILES : C#CC1CCC(N1C(=O)C(C2CCCC2)N)C=N
InChI : InChI=1S\/C14H21N3O\/c1-2-11-7-8-12(9-15)17(11)14(18)13(16)10-5-3-4-6-10\/h1,9-13,15H,3-8,16H2\/t11-,12-,13-\/m0\/s1
InChIKey : GRQIETUUMXGWJG-AVGNSLFASA-N
Other name(s) : AIA
MW : 247.34
Formula : C14H21N3O
CAS_number :
PubChem : 23586170
UniChem : GRQIETUUMXGWJG-AVGNSLFASA-N
Target
Families : Alkynyl-cyanopyrrolidine-1 ligand of proteins in family
DPP4N_Peptidase_S9
Structure :
2GBF
Protein :
ratno-dpp4
References (1)
| Title : Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors - Longenecker_2006_Biochemistry_45_7474 |
| Author(s) : Longenecker KL , Stewart KD , Madar DJ , Jakob CG , Fry EH , Wilk S , Lin CW , Ballaron SJ , Stashko MA , Lubben TH , Yong H , Pireh D , Pei Z , Basha F , Wiedeman PE , von Geldern TW , Trevillyan JM , Stoll VS |
| Ref : Biochemistry , 45 :7474 , 2006 |
| Abstract : |
| PubMedSearch : Longenecker_2006_Biochemistry_45_7474 |
| PubMedID: 16768443 |
| Gene_locus related to this paper: ratno-dpp4 |