Armin
Armin is a reversible organophosphorus cholinesterase inhibitor. It also affects the presynaptic membrane and inhibits membrane postsynaptic cholinergic receptors. The compound had former use as a miotic
General
Type : Chemical Warfare Agent, Organophosphate, pNP
Chemical_Nomenclature : 1-[ethoxy(ethyl)phosphoryl]oxy-4-nitrobenzene
Canonical SMILES : CCOP(=O)(CC)OC1=CC=C(C=C1)[N+](=O)[O-]
InChI : InChI=1S\/C10H14NO5P\/c1-3-15-17(14,4-2)16-10-7-5-9(6-8-10)11(12)13\/h5-8H,3-4H2,1-2H3
InChIKey : XXUJMEYKYHETBZ-UHFFFAOYSA-N
Other name(s) : Arminum || Arminium || Armine || O-ethyl-O-(4-nitrophenyl)ethyl phosphonatenitrophenyl ethylphosphonate || p-Nitrophenyl-O-ethyl ethylphosphonate || Ethyl p-nitrophenyl ethylphosphonate || Ethyl-4-nitrophenyl ethylphosphonate || Ethoxy-4-nitrophenyloxyethyl-phosphineoxide
MW : 259.196
Formula : C10H14NO5P
CAS_number :
PubChem : 66067
UniChem : XXUJMEYKYHETBZ-UHFFFAOYSA-N
Target
Families : Armin ligand of proteins in family
ACHE
References (5)
| Title : Mechanisms of cardiac muscle insensitivity to a novel acetylcholinesterase inhibitor C-547 - Abramochkin_2009_J.Cardiovasc.Pharmacol_53_162 |
| Author(s) : Abramochkin DV , Petrov KA , Zobov VV , Yagodina LO , Nikolsky EE , Rosenshtraukh LV |
| Ref : J Cardiovasc Pharmacol , 53 :162 , 2009 |
| Abstract : |
| PubMedSearch : Abramochkin_2009_J.Cardiovasc.Pharmacol_53_162 |
| PubMedID: 19188831 |
| Title : [Protection of mice by carbamates cholinesterase inhibitors against poisoning by armin and its dependence on certain physico-chemical indicators] - Prozorovskii_1999_Vopr.Med.Khim_45_525 |
| Author(s) : Prozorovskii VB , Pavlova LV , Suslova IM , Sazonova AV , Kokushkina AV |
| Ref : Vopr Med Khim , 45 :525 , 1999 |
| Abstract : |
| PubMedSearch : Prozorovskii_1999_Vopr.Med.Khim_45_525 |
| PubMedID: 10761219 |
| Title : [The effect of armin on neuromuscular transmission in the frog against a background of hexadecamethonium action]. [Russian] - Grigor'ev_1995_Fiziol.Zh.Im.I.M.Sechenova_81_27 |
| Author(s) : Grigor'ev VM |
| Ref : Fiziologicheskii Zhurnal , 81 :27 , 1995 |
| Abstract : |
| PubMedSearch : Grigor'ev_1995_Fiziol.Zh.Im.I.M.Sechenova_81_27 |
| PubMedID: 8714372 |
| Title : [Catalytic properties of cholinesterases immobilized in a gelatin membrane] - Kuznetsova_1990_Ukr.Biokhim.Zh_62_42 |
| Author(s) : Kuznetsova LP , Kugusheva LI , Nikol'skaia EB |
| Ref : Ukr Biokhim Zh , 62 :42 , 1990 |
| Abstract : |
| PubMedSearch : Kuznetsova_1990_Ukr.Biokhim.Zh_62_42 |
| PubMedID: 2087792 |
| Title : [Effect of armin and dipyroxime on the nicotinamide coenzyme and adenine nucleotide content of the rat myocardium and liver]. [Russian] - Tikhonenko_1982_Farmakol.Toksikol_45_26 |
| Author(s) : Tikhonenko VM |
| Ref : Farmakologiia i Toksikologiia , 45 :26 , 1982 |
| Abstract : |
| PubMedSearch : Tikhonenko_1982_Farmakol.Toksikol_45_26 |
| PubMedID: 82117539 |