BDBM243037
IC50 AChE 0.011 microM BChE >100
General
Type : Sulfur Compound, Thiazole, Piperazine
Chemical_Nomenclature : 2-(4-benzylpiperazin-1-yl)-N-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]acetamide
Canonical SMILES : CC1=NC(=CS1)C2=CC=C(C=C2)NC(=O)CN3CCN(CC3)CC4=CC=CC=C4
InChI : InChI=1S\/C23H26N4OS\/c1-18-24-22(17-29-18)20-7-9-21(10-8-20)25-23(28)16-27-13-11-26(12-14-27)15-19-5-3-2-4-6-19\/h2-10,17H,11-16H2,1H3,(H,25,28)
InChIKey : DANSGGXPZCCSQD-UHFFFAOYSA-N
Other name(s) : Compound 5o
MW : 406.5
Formula : C23H26N4OS
CAS_number :
PubChem : 73443010
UniChem : DANSGGXPZCCSQD-UHFFFAOYSA-N
Target
Families : BDBM243037 ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Design, synthesis and evaluation of new thiazole-piperazines as acetylcholinesterase inhibitors - Yurttas_2013_J.Enzyme.Inhib.Med.Chem_28_1040 |
| Author(s) : Yurttas L , Kaplancikli ZA , Ozkay Y |
| Ref : J Enzyme Inhib Med Chem , 28 :1040 , 2013 |
| Abstract : |
| PubMedSearch : Yurttas_2013_J.Enzyme.Inhib.Med.Chem_28_1040 |
| PubMedID: 22871134 |