Benzyl-piperazinyl-propylamino-nitrophenyl-phenyl-triazole-Cpd11n
AChE IC50 0.55 microM nM; IC50 BChE 12.45 microM
General
Type : Nitrobenzyl, Piperazine, Triazol
Chemical_Nomenclature : 3-[3-(4-benzylpiperazin-1-yl)propylamino]-5-(4-nitrophenyl)-1-phenyl-1H-1,2,4-triazole
Canonical SMILES : C1(=N[N](C(=N1)C2=CC=C([N+](=O)[O-])C=C2)C3=CC=CC=C3)NCCCN4CCN(CC4)CC5=CC=CC=C5
InChI : InChI=1S\/C28H31N7O2\/c36-35(37)26-14-12-24(13-15-26)27-30-28(31-34(27)25-10-5-2-6-11-25)29-16-7-17-32-18-20-33(21-19-32)22-23-8-3-1-4-9-23\/h1-6,8-15H,7,16-22H2,(H,29,31)
InChIKey : ANSSFUQDXTZFPC-UHFFFAOYSA-N
Other name(s) : Compound 11n || 3-[3-(4-Benzyl-1-piperazinyl)propylamino]-5-(p-nitrophenyl)-1-phenyl-1H-1,2,4-triazole
Target
Families : Benzyl-piperazinyl-propylamino-nitrophenyl-phenyl-triazole-Cpd11n ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Synthesis and Pharmacological Evaluation of Novel 1,5-Disubstituted-3-amino-1,2,4-triazoles Designed as Multitarget Directed Ligands for Alzheimer's Disease Targets - Franco_2026_ACS.Omega_11_13184 |
| Author(s) : Franco DP , Caruso L , Grillo DCN , Nadur NF , de Azevedo LL , Pereira TM , da Silva MC , Lacerda RB , Pinheiro PSM , Riger CJ , Kummerle AE |
| Ref : ACS Omega , 11 :13184 , 2026 |
| Abstract : |
| PubMedSearch : Franco_2026_ACS.Omega_11_13184 |
| PubMedID: 41799150 |