Benzyloxy-phenylthiazol-ylidenehydrazonomethyl-chromenone-Cpd5b
IC50 ACHE 0.451 microM
General
Type : Chromen, Thiazole, Sulfur Compound, Coumarin
Chemical_Nomenclature : 7-benzyloxy-4-{[(4-phenylthiazol-2(3H)-ylidene)hydrazono]methyl}-2H-chromen-2-one
Canonical SMILES : C1=CC(=CC2=C1C(=CC(O2)=O)C=NN=C3NC(=CS3)C4=CC=CC=C4)OCC5=CC=CC=C5
InChI : InChI=1S\/C26H19N3O3S\/c30-25-13-20(15-27-29-26-28-23(17-33-26)19-9-5-2-6-10-19)22-12-11-21(14-24(22)32-25)31-16-18-7-3-1-4-8-18\/h1-15,17H,16H2,(H,28,29)
InChIKey : KKJSJFUHQYSZNL-UHFFFAOYSA-N
Other name(s) : Compound 5b
Target
Families : Benzyloxy-phenylthiazol-ylidenehydrazonomethyl-chromenone-Cpd5b ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Design and synthesis of novel coumarin derivatives as potential acetylcholinesterase inhibitors for Alzheimer's disease - Amin_2021_Bioorg.Chem_110_104792 |
| Author(s) : Amin KM , Abdel Rahman DE , Abdelrasheed Allam H , El-Zoheiry HH |
| Ref : Bioorg Chem , 110 :104792 , 2021 |
| Abstract : |
| PubMedSearch : Amin_2021_Bioorg.Chem_110_104792 |
| PubMedID: 33799178 |