Biotin-PEG3-(2-Chloroethyl)benzene
Bait ligands for phage display of StEH1 variants for promiscuous dehalogenase activity of an epoxide hydrolase. Bound phage-StEH1 particles attached to the bait ligand were trapped onto streptavidin coated paramagnetic beads
General
Type : Sulfur Compound, Biotin derivative
Chemical_Nomenclature : [(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl] propoxy]ethoxy]ethoxy](2-Bromoethyl)benzene
Canonical SMILES : [C@H]2(CCCCC(NCCOCCOCCOCCNC(NC1=CC=C(C=C1)CCCCl)=O)=O)[C@@H]3[C@H](CS2)NC(N3)=O
InChI : InChI=1S\/C28H44ClN5O6S\/c29-11-3-4-21-7-9-22(10-8-21)32-27(36)31-13-15-39-17-19-40-18-16-38-14-12-30-25(35)6-2-1-5-24-26-23(20-41-24)33-28(37)34-26\/h7-10,23-24,26H,1-6,11-20H2,(H,30,35)(H2,31,32,36)(H2,33,34,37)\/t23-,24-,26-\/m0\/s1
InChIKey : SNRWLRSPBUYOSE-GNKBHMEESA-N
Other name(s) :
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Target
Families : Biotin-PEG3-(2-Chloroethyl)benzene ligand of proteins in family
Epoxide_hydrolase
Protein :
soltu-3epoxy
References (1)
| Title : High-throughput selection of (new) enzymes: phage display-mediated isolation of alkyl halide hydrolases from a library of active-site mutated epoxide hydrolases - Blazic_2024_Faraday.Discuss__ |
| Author(s) : Blazic M , Gautier C , Norberg T , Widersten M |
| Ref : Faraday Discussion , : , 2024 |
| Abstract : |
| PubMedSearch : Blazic_2024_Faraday.Discuss__ |
| PubMedID: 38828992 |
| Gene_locus related to this paper: soltu-3epoxy |