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Biotin derivative

General

Biotin is also called vitamin B7, is one of the B vitamins. Biotin is a coenzyme for five carboxylase enzymes, which are involved in the digestion of carbohydrates, synthesis of fatty acids, and gluconeogenesis. Biotinylated compounds of interest can be isolated from a sample by using avidin compounds which binds strongly to biotin. Used biochemical probes
Inhibitor Main targeted enzyme families Type Structure
Biotin-PEG3-(2-Chloroethyl)benzene Epoxide_hydrolase Sulfur Compound Biotin derivative Organochlorine
Desthiobiotin-PEG3-Azide Carbon-carbon_bond_hydrolase Azido ABPP-Probe Biotin derivative Imidazole
S9B Organophosphate Cyclic OP NTE inhibitor OPIDN-OP Not AlphaBeta Hydrolase target Sulfur Compound Biotin derivative
VX-Biotin Carboxypeptidase_S10 ACHE BCHE A85-EsteraseD-FGH ACPH_Peptidase_S9 Carb_B_Chordata Hormone-sensitive_lipase_like LYsophospholipase_carboxylesterase Lipase_3 Monoglyceridelipase_lysophospholip Arylacetamide_deacetylase Thioesterase DPP4N_Peptidase_S9 PC-sterol_acyltransferase ABHD6-Lip PAF-Acetylhydrolase S9N_PREPL_Peptidase_S9 PPase_methylesterase_euk Kynurenine-formamidase Organophosphate ABPP-Probe Imidazole Sulfur Compound Biotin derivative Derivative of VX
FP-Biotin Organophosphate ABPP-Probe Imidazole Sulfur Compound Biotin derivative
FP-Desthiobiotin LIDHydrolase Organophosphate ABPP-Probe Biotin derivative Imidazole
Nitrophenyl-methyl-p-biotinamidophenylmethylphosphonate BCHE Organophosphate pNP Sulfur Compound Biotin derivative
Biotin-PEG3-(2-Chloroethyl)benzene Epoxide_hydrolase Sulfur compound Biotin derivative Organochlorine
Desthiobiotin-PEG3-Azide Carbon-carbon_bond_hydrolase Azido ABPP-Probe Biotin derivative Imidazole
S9B Organophosphate Cyclic OP NTE inhibitor OPIDN-OP Not AlphaBeta Hydrolase target Sulfur compound Biotin derivative
VX-Biotin Carboxypeptidase_S10 ACHE BCHE A85-EsteraseD-FGH ACPH_Peptidase_S9 Carb_B_Chordata Hormone-sensitive_lipase_like LYsophospholipase_carboxylesterase Lipase_3 Monoglyceridelipase_lysophospholip Arylacetamide_deacetylase Thioesterase DPP4N_Peptidase_S9 PC-sterol_acyltransferase ABHD6-Lip PAF-Acetylhydrolase S9N_PREPL_Peptidase_S9 PPase_methylesterase_euk Kynurenine-formamidase Organophosphate ABPP-Probe Imidazole Sulfur compound Biotin derivative Derivative of VX
FP-Biotin Organophosphate ABPP-Probe Imidazole Sulfur compound Biotin derivative
FP-Desthiobiotin LIDHydrolase Organophosphate ABPP-Probe Biotin derivative Imidazole
Nitrophenyl-methyl-p-biotinamidophenylmethylphosphonate BCHE Organophosphate pNP Sulfur compound Biotin derivative