soltu-3epoxy
Solanum tuberosum (Potato) StEH1 Lemhi Russet clone EH10.1 epoxide hydrolase
Comment
Relationship
Family : Epoxide_hydrolase
Block : X
Position in NCBI Life Tree : Solanum tuberosum
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Viridiplantae N E > Streptophyta N E > Streptophytina N E > Embryophyta N E > Tracheophyta N E > Euphyllophyta N E > Spermatophyta N E > Magnoliophyta N E > Mesangiospermae N E > eudicotyledons N E > Gunneridae N E > Pentapetalae N E > asterids N E > lamiids N E > Solanales N E > Solanaceae N E > Solanoideae N E > Solaneae N E > Solanum N E > Solanum tuberosum N EMolecular evidence
No mutation
2CJP - Structure of potato (Solanum tuberosum) epoxide hydrolase I (StEH1)
3CXU - Structure of a Y149F mutant of epoxide hydrolase from Solanum tuberosum
4UFN - Laboratory evolved variant R-C1B1 of potato epoxide hydrolase StEH1
4UFO - Laboratory evolved variant R-C1B1D33E6 of potato epoxide hydrolase StEH1
4UFP - Laboratory evolved variant R-C1B1D33 of potato epoxide hydrolase StEH1
4UHB - Laboratory evolved variant R-C1 of potato epoxide hydrolase StEH1
4Y9S - Structure of an H300N mutant of potato epoxide hydrolase, StEH1
No kinetic
No disease
Sequence
Peptide
MEKIEHKMVA VNGLNMHLAE LGEGPTILFI HGFPELWYSW RHQMVYLAER GYRAVAPDLR GYGDTTGAPL NDPSKFSILH LVGDVVALLE AIAPNEEKVF VVAHDWGALI AWHLCLFRPD KVKALVNLSV HFSKRNPKMN VVEGLKAIYG EDHYISRFQV PGEIEAEFAP IGAKSVLKKI LTYRDPAPFY FPKGKGLEAI PDAPVALSSW LSEEELDYYA NKFEQTGFTG AVNYYRALPI NWELTAPWTG AQVKVPTKFI VGEFDLVYHI PGAKEYIHNG GFKKDVPLLE EVVVLEGAAH FVSQERPHEI SKHIYDFIQK F
References (15)
| Title : High-throughput selection of (new) enzymes: phage display-mediated isolation of alkyl halide hydrolases from a library of active-site mutated epoxide hydrolases - Blazic_2024_Faraday.Discuss__ |
| Author(s) : Blazic M , Gautier C , Norberg T , Widersten M |
| Ref : Faraday Discussion , : , 2024 |
| Abstract : |
| PubMedSearch : Blazic_2024_Faraday.Discuss__ |
| PubMedID: 38828992 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Water will Find Its Way: Transport through Narrow Tunnels in Hydrolases - Sequeiros-Borja_2024_J.Chem.Inf.Model__ |
| Author(s) : Sequeiros-Borja C , Surpeta B , Thirunavukarasu AS , Dongmo Foumthuim CJ , Marchlewski I , Brezovsky J |
| Ref : J Chem Inf Model , : , 2024 |
| Abstract : |
| PubMedSearch : Sequeiros-Borja_2024_J.Chem.Inf.Model__ |
| PubMedID: 38669675 |
| Gene_locus related to this paper: canru-1lipa , rhoso-halo1 , soltu-3epoxy , human-EPHX2 |
| Title : Epoxide hydrolysis as a model system for understanding flux through a branched reaction scheme - Janfalk_2018_IUCrJ_5_269 |
| Author(s) : Janfalk Carlsson A , Bauer P , Dobritzsch D , Kamerlin SCL , Widersten M |
| Ref : IUCrJ , 5 :269 , 2018 |
| Abstract : |
| PubMedSearch : Janfalk_2018_IUCrJ_5_269 |
| PubMedID: 29755743 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Exploring Solanum tuberosum Epoxide Hydrolase Internal Architecture by Water Molecules Tracking - Mitusinska_2018_Biomolecules_8_ |
| Author(s) : Mitusinska K , Magdziarz T , Bzowka M , Stanczak A , Gora A |
| Ref : Biomolecules , 8 : , 2018 |
| Abstract : |
| PubMedSearch : Mitusinska_2018_Biomolecules_8_ |
| PubMedID: 30424576 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Laboratory-Evolved Enzymes Provide Snapshots of the Development of Enantioconvergence in Enzyme-Catalyzed Epoxide Hydrolysis - Janfalk_2016_Chembiochem_17_1693 |
| Author(s) : Janfalk Carlsson A , Bauer P , Dobritzsch D , Nilsson M , Kamerlin SC , Widersten M |
| Ref : Chembiochem , 17 :1693 , 2016 |
| Abstract : |
| PubMedSearch : Janfalk_2016_Chembiochem_17_1693 |
| PubMedID: 27383542 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Conformational diversity and enantioconvergence in potato epoxide hydrolase 1 - Bauer_2016_Org.Biomol.Chem_14_5639 |
| Author(s) : Bauer P , Carlsson AJ , Amrein BA , Dobritzsch D , Widersten M , Kamerlin SC |
| Ref : Org Biomol Chem , 14 :5639 , 2016 |
| Abstract : |
| PubMedSearch : Bauer_2016_Org.Biomol.Chem_14_5639 |
| PubMedID: 27049844 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes - Amrein_2015_ACS.Catal_5_5702 |
| Author(s) : Amrein BA , Bauer P , Duarte F , Carlsson AJ , Naworyta A , Mowbray SL , Widersten M , Kamerlin SCL |
| Ref : ACS Catal , 5 :5702 , 2015 |
| Abstract : |
| PubMedSearch : Amrein_2015_ACS.Catal_5_5702 |
| PubMedID: 26527505 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Mutations in salt-bridging residues at the interface of the core and lid domains of epoxide hydrolase StEH1 affect regioselectivity, protein stability and hysteresis - Lindberg_2010_Arch.Biochem.Biophys_495_165 |
| Author(s) : Lindberg D , Ahmad S , Widersten M |
| Ref : Archives of Biochemistry & Biophysics , 495 :165 , 2010 |
| Abstract : |
| PubMedSearch : Lindberg_2010_Arch.Biochem.Biophys_495_165 |
| PubMedID: 20079707 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Temperature and pH dependence of enzyme-catalyzed hydrolysis of trans-methylstyrene oxide. A unifying kinetic model for observed hysteresis, cooperativity, and regioselectivity - Lindberg_2010_Biochemistry_49_2297 |
| Author(s) : Lindberg D , de la Fuente Revenga M , Widersten M |
| Ref : Biochemistry , 49 :2297 , 2010 |
| Abstract : |
| PubMedSearch : Lindberg_2010_Biochemistry_49_2297 |
| PubMedID: 20146441 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Removal of distal protein-water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability - Thomaeus_2008_Protein.Sci_17_1275 |
| Author(s) : Thomaeus A , Naworyta A , Mowbray SL , Widersten M |
| Ref : Protein Science , 17 :1275 , 2008 |
| Abstract : |
| PubMedSearch : Thomaeus_2008_Protein.Sci_17_1275 |
| PubMedID: 18515642 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Active site of epoxide hydrolases revisited: a noncanonical residue in potato StEH1 promotes both formation and breakdown of the alkylenzyme intermediate - Thomaeus_2007_Biochemistry_46_2466 |
| Author(s) : Thomaeus A , Carlsson J , Aqvist J , Widersten M |
| Ref : Biochemistry , 46 :2466 , 2007 |
| Abstract : |
| PubMedSearch : Thomaeus_2007_Biochemistry_46_2466 |
| PubMedID: 17284015 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : X-ray structure of potato epoxide hydrolase sheds light on substrate specificity in plant enzymes - Mowbray_2006_Protein.Sci_15_1628 |
| Author(s) : Mowbray SL , Elfstrom LT , Ahlgren KM , Andersson CE , Widersten M |
| Ref : Protein Science , 15 :1628 , 2006 |
| Abstract : |
| PubMedSearch : Mowbray_2006_Protein.Sci_15_1628 |
| PubMedID: 16751602 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Implications for an ionized alkyl-enzyme intermediate during StEH1-catalyzed trans-stilbene oxide hydrolysis - Elfstrom_2006_Biochemistry_45_205 |
| Author(s) : Elfstrom LT , Widersten M |
| Ref : Biochemistry , 45 :205 , 2006 |
| Abstract : |
| PubMedSearch : Elfstrom_2006_Biochemistry_45_205 |
| PubMedID: 16388596 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Catalysis of potato epoxide hydrolase, StEH1 - Elfstrom_2005_Biochem.J_390_633 |
| Author(s) : Elfstrom LT , Widersten M |
| Ref : Biochemical Journal , 390 :633 , 2005 |
| Abstract : |
| PubMedSearch : Elfstrom_2005_Biochem.J_390_633 |
| PubMedID: 15882148 |
| Gene_locus related to this paper: soltu-3epoxy |
| Title : Cloning and expression of soluble epoxide hydrolase from potato - Stapleton_1994_Plant.J_6_251 |
| Author(s) : Stapleton A , Beetham JK , Pinot F , Garbarino JE , Rockhold DR , Friedman M , Hammock BD , Belknap WR |
| Ref : Plant J , 6 :251 , 1994 |
| Abstract : |
| PubMedSearch : Stapleton_1994_Plant.J_6_251 |
| PubMedID: 7920715 |
| Gene_locus related to this paper: soltu-1epoxy , soltu-2epoxy , soltu-3epoxy , soltu-4epoxy , soltu-5epoxy |