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Bis(N-propylcarbamic-acid)ethylene-ester

1,2-Ethylene-di-N-n-propylcarbamate is an essential activator of Pseudomonas species lipase while 1,2-ethylene-di-N-n-butyl-, t-butyl-, n-heptyl-, and n-octyl-carbamates are inhibitors in the presence of the detergent taurocholate or triton X-100. It binds outside the active site of PSL and probably at the co-lipase binding site of Pseudomonas species lipase

General

Type : Carbamate

Chemical_Nomenclature : 2-(propylcarbamoyloxy)ethyl N-propylcarbamate

Canonical SMILES : CCCNC(=O)OCCOC(=O)NCCC

InChI : InChI=1S\/C10H20N2O4\/c1-3-5-11-9(13)15-7-8-16-10(14)12-6-4-2\/h3-8H2,1-2H3,(H,11,13)(H,12,14)

InChIKey : HYFRFSBFAPEDJM-UHFFFAOYSA-N

Other name(s) : Bis(N-propylcarbamic acid)ethylene ester  ||  1,2-Ethylene-di-N-n-propylcarbamate

MW : 232.28

Formula : C10H20N2O4

CAS_number :

PubChem : 101852196

UniChem : HYFRFSBFAPEDJM-UHFFFAOYSA-N

Target

Families : Bis(N-propylcarbamic-acid)ethylene-ester ligand of proteins in family
Bacterial_lip_FamI.1

Protein :
pseae-llipa

References (1)

Title : Inhibition or activation of Pseudomonas species lipase by 1,2-ethylene-di-N-alkylcarbamates in detergents - Lin_2007_Chem.Phys.Lipids_146_85
Author(s) : Lin MC , Lu CP , Cheng YR , Lin YF , Lin CS , Lin G
Ref : Chemistry & Physic of Lipids , 146 :85 , 2007
Abstract :
PubMedSearch : Lin_2007_Chem.Phys.Lipids_146_85
PubMedID: 17274971