pseae-llipa
Pseudomonas aeruginosa gene for lactonizing lipase triacylglycerol lipase (EC 3.1.1.3) lip lipA PA2862 PaLipA
Comment
Other strains: Pseudomonas aeruginosa (strain LESB58\; UCBPP-PA14\; 2192\; PA7\; 39016\; C3719), Pseudomonas sp. 42A2
Relationship
Family : Bacterial_lip_FamI.1
Block : L
Position in NCBI Life Tree : Pseudomonas aeruginosa
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Proteobacteria N E > Gammaproteobacteria N E > Pseudomonadales N E > Pseudomonadaceae N E > Pseudomonas N E > Pseudomonas aeruginosa group N E > Pseudomonas aeruginosa N EMolecular evidence
Database
Sequence
Peptide
MKKKSLLPLG LAIGLASLAA SPLIQASTYT QTKYPIVLAH GMLGFDNILG VDYWFGIPSA LRRDGAQVYV TEVSQLDTSE VRGEQLLQQV EEIVALSGQP KVNLIGHSHG GPTIRYVAAV RPDLIASATS VGAPHKGSDT ADFLRQIPPG SAGEAVLSGL VNSLGALISF LSSGSTGTQN SLGSLESLNS EGAARFNAKY PQGIPTSACG EGAYKVNGVS YYSWSGSSPL TNFLDPSDAF LGASSLTFKN GTANDGLVGT CSSHLGMVIR DNYRMNHLDE VNQVFGLTSL FETSPVSVYR QHANRLKNAS L
References (29)
| Title : The Membrane-Integrated Steric Chaperone Lif Facilitates Active Site Opening of Pseudomonas aeruginosa Lipase A - Verma_2020_J.Comput.Chem_41_500 |
| Author(s) : Verma N , Dollinger P , Kovacic F , Jaeger KE , Gohlke H |
| Ref : J Comput Chem , 41 :500 , 2020 |
| Abstract : |
| PubMedSearch : Verma_2020_J.Comput.Chem_41_500 |
| PubMedID: 31618459 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation - Viegas_2020_Sci.Rep_10_3578 |
| Author(s) : Viegas A , Dollinger P , Verma N , Kubiak J , Viennet T , Seidel CAM , Gohlke H , Etzkorn M , Kovacic F , Jaeger KE |
| Ref : Sci Rep , 10 :3578 , 2020 |
| Abstract : |
| PubMedSearch : Viegas_2020_Sci.Rep_10_3578 |
| PubMedID: 32107397 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Understanding domain movements and interactions of Pseudomonas aeruginosa lipase with lipid molecule tristearoyl glycerol: A molecular dynamics approach - Thiruvengadam_2018_J.Mol.Graph.Model_85_190 |
| Author(s) : Thiruvengadam K , Baskaran SK , Pennathur G |
| Ref : J Mol Graph Model , 85 :190 , 2018 |
| Abstract : |
| PubMedSearch : Thiruvengadam_2018_J.Mol.Graph.Model_85_190 |
| PubMedID: 30227364 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Pressure-induced conformational switch of an interfacial protein - Johnson_2016_Proteins_84_820 |
| Author(s) : Johnson QR , Lindsay RJ , Nellas RB , Shen T |
| Ref : Proteins , 84 :820 , 2016 |
| Abstract : |
| PubMedSearch : Johnson_2016_Proteins_84_820 |
| PubMedID: 26967808 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Solvent-Dependent Gating Motions of an Extremophilic Lipase from Pseudomonas aeruginosa - Johnson_2012_Biochemistry_51_6238 |
| Author(s) : Johnson QR , Nellas RB , Shen T |
| Ref : Biochemistry , 51 :6238 , 2012 |
| Abstract : |
| PubMedSearch : Johnson_2012_Biochemistry_51_6238 |
| PubMedID: 22830585 |
| Gene_locus related to this paper: pseae-llipa |
| Title : In vivo functional expression of a screened P. aeruginosa chaperone-dependent lipase in E. coli - Wu_2012_BMC.Biotechnol_12_58 |
| Author(s) : Wu X , You P , Su E , Xu J , Gao B , Wei D |
| Ref : BMC Biotechnol , 12 :58 , 2012 |
| Abstract : |
| PubMedSearch : Wu_2012_BMC.Biotechnol_12_58 |
| PubMedID: 22950599 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Revisiting the lipase from Pseudomonas aeruginosa: directed evolution of substrate acceptance and enantioselectivity using iterative saturation mutagenesis - Prasad_2011_Chemphyschem_12_1550 |
| Author(s) : Prasad S , Bocola M , Reetz MT |
| Ref : Chemphyschem , 12 :1550 , 2011 |
| Abstract : |
| PubMedSearch : Prasad_2011_Chemphyschem_12_1550 |
| PubMedID: 21472964 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Differential behaviour of Pseudomonas sp. 42A2 LipC, a lipase showing greater versatility than its counterpart LipA - Bofill_2010_Biochimie_92_307 |
| Author(s) : Bofill C , Prim N , Mormeneo M , Manresa A , Pastor FI , Diaz P |
| Ref : Biochimie , 92 :307 , 2010 |
| Abstract : |
| PubMedSearch : Bofill_2010_Biochimie_92_307 |
| PubMedID: 19944735 |
| Gene_locus related to this paper: pseae-clipa , pseae-llipa |
| Title : Co-expression of the lipase and foldase of Pseudomonas aeruginosa to a functional lipase in Escherichia coli - Madan_2010_Appl.Microbiol.Biotechnol_85_597 |
| Author(s) : Madan B , Mishra P |
| Ref : Applied Microbiology & Biotechnology , 85 :597 , 2010 |
| Abstract : |
| PubMedSearch : Madan_2010_Appl.Microbiol.Biotechnol_85_597 |
| PubMedID: 19629472 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Mutations towards enantioselectivity adversely affect secretion of Pseudomonas aeruginosa lipase - Hausmann_2008_FEMS.Microbiol.Lett_282_65 |
| Author(s) : Hausmann S , Wilhelm S , Jaeger KE , Rosenau F |
| Ref : FEMS Microbiology Letters , 282 :65 , 2008 |
| Abstract : |
| PubMedSearch : Hausmann_2008_FEMS.Microbiol.Lett_282_65 |
| PubMedID: 18355276 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Cloning and expression of gene, and activation of an organic solvent-stable lipase from Pseudomonas aeruginosa LST-03 - Ogino_2007_Extremophiles_11_809 |
| Author(s) : Ogino H , Katou Y , Akagi R , Mimitsuka T , Hiroshima S , Gemba Y , Doukyu N , Yasuda M , Ishimi K , Ishikawa H |
| Ref : Extremophiles , 11 :809 , 2007 |
| Abstract : |
| PubMedSearch : Ogino_2007_Extremophiles_11_809 |
| PubMedID: 17657406 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Activation Mechanisms for Pseudomonas species Lipase by Cardiovascular Drugs in Vitro - Lin_2007_J.Chin.Chem.Soc_54_1601 |
| Author(s) : Lin MC , Lai GW , Lin CS , Lin G |
| Ref : Journal of the Chinese Chemical Society , 54 :1601 , 2007 |
| Abstract : |
| PubMedSearch : Lin_2007_J.Chin.Chem.Soc_54_1601 |
| PubMedID: |
| Gene_locus related to this paper: pseae-llipa |
| Title : Expanding the substrate scope of enzymes: combining mutations obtained by CASTing - Reetz_2006_Chemistry_12_6031 |
| Author(s) : Reetz MT , Carballeira JD , Peyralans J , Hobenreich H , Maichele A , Vogel A |
| Ref : Chemistry , 12 :6031 , 2006 |
| Abstract : |
| PubMedSearch : Reetz_2006_Chemistry_12_6031 |
| PubMedID: 16789057 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Directed evolution of Pseudomonas aeruginosa lipase for improved amide-hydrolyzing activity - Fujii_2005_Protein.Eng.Des.Sel_18_93 |
| Author(s) : Fujii R , Nakagawa Y , Hiratake J , Sogabe A , Sakata K |
| Ref : Protein Engineering Des Sel , 18 :93 , 2005 |
| Abstract : |
| PubMedSearch : Fujii_2005_Protein.Eng.Des.Sel_18_93 |
| PubMedID: 15788423 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Expanding the range of substrate acceptance of enzymes: combinatorial active-site saturation test - Reetz_2005_Angew.Chem.Int.Ed.Engl_44_4192 |
| Author(s) : Reetz MT , Bocola M , Carballeira JD , Zha D , Vogel A |
| Ref : Angew Chem Int Ed Engl , 44 :4192 , 2005 |
| Abstract : |
| PubMedSearch : Reetz_2005_Angew.Chem.Int.Ed.Engl_44_4192 |
| PubMedID: 15929154 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity - Bocola_2004_Chembiochem_5_214 |
| Author(s) : Bocola M , Otte N , Jaeger KE , Reetz MT , Thiel W |
| Ref : Chembiochem , 5 :214 , 2004 |
| Abstract : |
| PubMedSearch : Bocola_2004_Chembiochem_5_214 |
| PubMedID: 14760743 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Controlling the enantioselectivity of enzymes by directed evolution: practical and theoretical ramifications - Reetz_2004_Proc.Natl.Acad.Sci.U.S.A_101_5716 |
| Author(s) : Reetz MT |
| Ref : Proc Natl Acad Sci U S A , 101 :5716 , 2004 |
| Abstract : |
| PubMedSearch : Reetz_2004_Proc.Natl.Acad.Sci.U.S.A_101_5716 |
| PubMedID: 15079053 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Characterization of the lipA gene encoding the major lipase from Pseudomonas aeruginosa strain IGB83 - Martinez_2001_Appl.Microbiol.Biotechnol_56_731 |
| Author(s) : Martinez A , Soberon-Chavez G |
| Ref : Applied Microbiology & Biotechnology , 56 :731 , 2001 |
| Abstract : |
| PubMedSearch : Martinez_2001_Appl.Microbiol.Biotechnol_56_731 |
| PubMedID: 11601622 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Disulfide bond in Pseudomonas aeruginosa lipase stabilizes the structure but is not required for interaction with its foldase - Liebeton_2001_J.Bacteriol_183_597 |
| Author(s) : Liebeton K , Zacharias A , Jaeger KE |
| Ref : Journal of Bacteriology , 183 :597 , 2001 |
| Abstract : |
| PubMedSearch : Liebeton_2001_J.Bacteriol_183_597 |
| PubMedID: 11133953 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Crystal structure of pseudomonas aeruginosa lipase in the open conformation. The prototype for family I.1 of bacterial lipases - Nardini_2000_J.Biol.Chem_275_31219 |
| Author(s) : Nardini M , Lang DA , Liebeton K , Jaeger KE , Dijkstra BW |
| Ref : Journal of Biological Chemistry , 275 :31219 , 2000 |
| Abstract : |
| PubMedSearch : Nardini_2000_J.Biol.Chem_275_31219 |
| PubMedID: 10893416 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Substitutions of Ser for Asn-163 and Pro for Leu-264 are important for stabilization of lipase from Pseudomonas aeruginosa - Shinkai_1996_J.Biochem_120_915 |
| Author(s) : Shinkai A , Hirano A , Aisaka K |
| Ref : J Biochem , 120 :915 , 1996 |
| Abstract : |
| PubMedSearch : Shinkai_1996_J.Biochem_120_915 |
| PubMedID: 8982856 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Molecular genetics of the extracellular lipase of Pseudomonas aeruginosa PAO1 - Wohlfarth_1992_J.Gen.Microbiol_138_1325 |
| Author(s) : Wohlfarth S , Hoesche C , Strunk C , Winkler UK |
| Ref : J Gen Microbiol , 138 :1325 , 1992 |
| Abstract : |
| PubMedSearch : Wohlfarth_1992_J.Gen.Microbiol_138_1325 |
| PubMedID: 1512563 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Extracellular lipase from Pseudomonas aeruginosa is an amphiphilic protein - Jaeger_1992_Biochim.Biophys.Acta_1120_315 |
| Author(s) : Jaeger KE , Adrian FJ , Meyer HE , Hancock RE , Winkler UK |
| Ref : Biochimica & Biophysica Acta , 1120 :315 , 1992 |
| Abstract : |
| PubMedSearch : Jaeger_1992_Biochim.Biophys.Acta_1120_315 |
| PubMedID: 1576157 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Purification, molecular cloning, and expression of lipase from Pseudomonas aeruginosa - Chihara-Siomi_1992_Arch.Biochem.Biophys_296_505 |
| Author(s) : Chihara-Siomi M , Yoshikawa K , Oshima-Hirayama N , Yamamoto K , Sogabe Y , Nakatani T , Nishioka T , Oda J |
| Ref : Archives of Biochemistry & Biophysics , 296 :505 , 1992 |
| Abstract : |
| PubMedSearch : Chihara-Siomi_1992_Arch.Biochem.Biophys_296_505 |
| PubMedID: 1632642 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Purification and properties of extracellular lipase from Pseudomonas aeruginosa EF2 - Gilbert_1991_J.Gen.Microbiol_137_2223 |
| Author(s) : Gilbert EJ , Cornish A , Jones CW |
| Ref : J Gen Microbiol , 137 :2223 , 1991 |
| Abstract : |
| PubMedSearch : Gilbert_1991_J.Gen.Microbiol_137_2223 |
| PubMedID: 1748875 |
| Gene_locus related to this paper: pseae-llipa |
| Title : Extracellular lipase of Pseudomonas aeruginosa: biochemical characterization and effect on human neutrophil and monocyte function in vitro - Jaeger_1991_Microb.Pathog_10_173 |
| Author(s) : Jaeger KE , Kharazmi A , Hoiby N |
| Ref : Microb Pathog , 10 :173 , 1991 |
| Abstract : |
| PubMedSearch : Jaeger_1991_Microb.Pathog_10_173 |
| PubMedID: 1910141 |
| Gene_locus related to this paper: pseae-llipa |