Bis(benzyloxy)phenyl)-hydroxy-chromen-one-Cpd8
Dual-acting flavonol analogue as cholinesterase inhibitors and anticonvulsant agent IC50 AChE 0.014 +/- 0.001 microM; IC50 AChE 7.854 1.26 +/- 0.04 microM
General
Type : Chromen, Flavonoid, Multitarget
Chemical_Nomenclature : 2-(2,4-Bis(benzyloxy)phenyl)-3-hydroxy-4H-chromen-4-one
Canonical SMILES : C1=CC=CC2=C1OC(=C(C2=O)O)C3=C(C=C(C=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5
InChI : InChI=1S\/C29H22O5\/c30-27-23-13-7-8-14-25(23)34-29(28(27)31)24-16-15-22(32-18-20-9-3-1-4-10-20)17-26(24)33-19-21-11-5-2-6-12-21\/h1-17,31H,18-19H2
InChIKey : YBBRNNOZQWMNOL-UHFFFAOYSA-N
Other name(s) :
phenyl)-hydroxy-chromen-one-Cpd8.gif)
Target
Families : Bis(benzyloxy)phenyl)-hydroxy-chromen-one-Cpd8 ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Dual-acting flavonol analogues as cholinesterase inhibitors and anticonvulsant agents: integrated in vitro, in vivo, and in silico studies - Mughal_2026_RSC.Adv__ |
| Author(s) : Mughal EU , Naeem N , Kilinc N , Ahmed I , Zaki MEA , Fathalla M , Sadiq A , Hefnawy M |
| Ref : RSC Adv , : , 2026 |
| Abstract : |
| PubMedSearch : Mughal_2026_RSC.Adv__ |
| PubMedID: 42699166 |