Bromo-benzofuran-phenoxy-heptyl-amine-benzyl-methyl
IC50 microM AChE 27.7 +/- 1.48 BChE 0.7 +/- 0.01
General
Type : Benzofuran, Alkyl linked bis-ligand
Chemical_Nomenclature : N-(benzyl)-N-(methyl){7-[3-(7-bromo-1-benzofuran-2-yl)phenyloxy]heptyl}amine
Canonical SMILES : C1=CC(=C2C(=C1)C=C(O2)C3=CC=CC(=C3)OCCCCCCCN(C)CC4=CC=CC=C4)Br
InChI : InChI=1S\/C29H32BrNO2\/c1-31(22-23-12-6-5-7-13-23)18-8-3-2-4-9-19-32-26-16-10-14-24(20-26)28-21-25-15-11-17-27(30)29(25)33-28\/h5-7,10-17,20-21H,2-4,8-9,18-19,22H2,1H3
InChIKey : FVRKQHJRVAVMMA-UHFFFAOYSA-N
Other name(s) : Compound 34 || N-Benzyl-N-methyl{7-[m-(7-bromo-1-benzofuran-2-yl)phenoxy]heptyl}amine
Target
Families : Bromo-benzofuran-phenoxy-heptyl-amine-benzyl-methyl ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : 2-Arylbenzofurans as Selective Cholinesterase Inhibitors: Design, Synthesis, and Evaluation as Alzheimer's Disease Agents - Delogu_2026_Biomolecules_16_ |
| Author(s) : Delogu GL , Begala M , Novas M , Matos MJ , Piras F , Floris S , Pintus F , Mancinelli M , Era B , Fais A |
| Ref : Biomolecules , 16 : , 2026 |
| Abstract : |
| PubMedSearch : Delogu_2026_Biomolecules_16_ |
| PubMedID: 41594719 |