Bromo-dihydroxyphenyl-benzene-sulfonamide-Cpd21
IC50 hcA-1 46.20; hcA-2 57.75; AChE 18.73 nM ; Ki hcA-1 50.13 +/- 9.47; hcA-2 23.52 +/- 2.16; AChE 2.29 +/- 0.63 nM
General
Type : Multitarget, Dimethoxyphenyl, Carbonic anhydrase inhibitor, Sulfur Compound, Sulfonamide
Chemical_Nomenclature : 2-Bromo-4,5-dihydroxy-N-phenyl benzene sulfonamide
Canonical SMILES : OC1=C(C=C(C(=C1)Br)[S](NC2=CC=CC=C2)(=O)=O)O
InChI : InChI=1S\/C12H10BrNO4S\/c13-9-6-10(15)11(16)7-12(9)19(17,18)14-8-4-2-1-3-5-8\/h1-7,14-16H
InChIKey : IAZGDKCSFQLPEH-UHFFFAOYSA-N
Other name(s) : Compound 21
Target
Families : Bromo-dihydroxyphenyl-benzene-sulfonamide-Cpd21 ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Synthesis of novel bromophenolic sulfonamides with their acetylcholinesterase and carbonic anhydrase inhibitory actions - Oztaskin_2026_Bioorg.Med.Chem.Lett__130599 |
| Author(s) : Oztaskin N , Etminan P , Akincioglu A , Cagan A , Demir Y , Goksu S , Gulcin I |
| Ref : Bioorganic & Medicinal Chemistry Lett , :130599 , 2026 |
| Abstract : |
| PubMedSearch : Oztaskin_2026_Bioorg.Med.Chem.Lett__130599 |
| PubMedID: 41765051 |