CHMP-S-ethyl

"can be synthetized as (Sp) or (P-) and (Rp) or (P+) stereoisomers"

General

Type : Organophosphate,Sulfur Compound

Chemical_Nomenclature : [ethylsulfanyl(methyl)phosphoryl]oxycycloheptane

Canonical SMILES : CCS[P](=O)(C)OC1CCCCCC1

InChI : InChI=1S\/C10H21O2PS\/c1-3-14-13(2,11)12-10-8-6-4-5-7-9-10\/h10H,3-9H2,1-2H3

InChIKey : PVRXMZHHAYEXFP-UHFFFAOYSA-N

Other name(s) : Cycloheptyl methyl S-ethylphosphonylthioate


MW : 263.31

Formula : C10H21O2PS

CAS_number :

PubChem : 85590433

UniChem : PVRXMZHHAYEXFP-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : CHMP-S-ethyl ligand of proteins in family: ACHE

Stucture :

Protein :

References (3)

Title : Aspartate 74 as a primary determinant in acetylcholinesterase governing specificity to cationic organophosphonates - Hosea_1996_Biochemistry_35_10995
Author(s) : Hosea NA , Radic Z , Tsigelny I , Berman HA , Quinn DM , Taylor P
Ref : Biochemistry , 35 :10995 , 1996
Abstract : Hosea_1996_Biochemistry_35_10995
ESTHER : Hosea_1996_Biochemistry_35_10995
PubMedSearch : Hosea_1996_Biochemistry_35_10995
PubMedID: 8718893

Title : Chiral reactions of acetylcholinesterase probed with enantiomeric methylphosphonothioates. Noncovalent determinants of enzyme chirality [published erratum appears in J Biol Chem 1989 Nov 25\;264(33):20154] - Berman_1989_J.Biol.Chem_264_3942
Author(s) : Berman HA , Leonard K
Ref : Journal of Biological Chemistry , 264 :3942 , 1989
Abstract : Berman_1989_J.Biol.Chem_264_3942
ESTHER : Berman_1989_J.Biol.Chem_264_3942
PubMedSearch : Berman_1989_J.Biol.Chem_264_3942
PubMedID: 2917983

Title : Chiral nature of covalent methylphosphonyl conjugates of acetylcholinesterase - Berman_1989_J.Biol.Chem_264_3951
Author(s) : Berman HA , Decker MM
Ref : Journal of Biological Chemistry , 264 :3951 , 1989
Abstract : Berman_1989_J.Biol.Chem_264_3951
ESTHER : Berman_1989_J.Biol.Chem_264_3951
PubMedSearch : Berman_1989_J.Biol.Chem_264_3951
PubMedID: 2917984