Carvacrol-quinolin-acetamide-cpd5v
AChE and BuChE with the IC50 values of 1.93 and 0.05 microM
General
Type : Carvacrol-Thymol, Carbamate
Chemical_Nomenclature : 2-(5-Isopropyl-2-methylphenoxy)-N-(quinolin-8-yl)acetamide
Canonical SMILES : C1=CC(=CC(=C1C)OC(NC2=C3C(=CC=C2)C=CC=N3)=O)C(C)C
InChI : InChI=1S\/C20H20N2O2\/c1-13(2)16-10-9-14(3)18(12-16)24-20(23)22-17-8-4-6-15-7-5-11-21-19(15)17\/h4-13H,1-3H3,(H,22,23)
InChIKey : GRWIKAFARNKJHV-UHFFFAOYSA-N
Other name(s) : Compound 5v
Target
Families : Carvacrol-quinolin-acetamide-cpd5v ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Synthesis, Anticholinesterase Activity and Molecular Modeling Studies of Novel Carvacrol Substituted Amide Derivatives - Zengin Kurt_2019_J.Biomol.Struct.Dyn__1 |
| Author(s) : Zengin Kurt B , Durdagi S , Celebi G , Ekhteiari Salmas R , Sonmez F |
| Ref : J Biomol Struct Dyn , :1 , 2019 |
| Abstract : |
| PubMedSearch : Zengin Kurt_2019_J.Biomol.Struct.Dyn__1 |
| PubMedID: 30836858 |