DHEA-imidazole-carboxylate
BChE IC50 = 0.1 microM
General
Chemical_Nomenclature : 5-androsten-17-one-3beta-yl imidazole-1-carboxylate
Canonical SMILES : C2[C@@H](CC1=CC[C@@H]3[C@@H]([C@]1(C2)C)CC[C@]4([C@H]3CCC4=O)C)OC([N]5C=NC=C5)=O
InChI : InChI=1S\/C23H30N2O3\/c1-22-9-7-16(28-21(27)25-12-11-24-14-25)13-15(22)3-4-17-18-5-6-20(26)23(18,2)10-8-19(17)22\/h3,11-12,14,16-19H,4-10,13H2,1-2H3\/t16-,17-,18-,19-,22-,23-\/m0\/s1
InChIKey : SBCMNEJCZGYKDF-VYAQIDIUSA-N
Other name(s) : Compound D8
Target
Families : DHEA-imidazole-carboxylate ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : DHEA-carbamate derivatives as dual cholinesterase inhibitors: Integration of enzymatic and biomolecular interactions in Alzheimer's disease - Nar_2025_Bioorg.Chem_164_108901 |
| Author(s) : Nar K , Erdagi SI , Ozbagci DI |
| Ref : Bioorg Chem , 164 :108901 , 2025 |
| Abstract : |
| PubMedSearch : Nar_2025_Bioorg.Chem_164_108901 |
| PubMedID: 40850285 |