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Imidazole

General

Building block for many inhibitors of enzymes
Inhibitor Main targeted enzyme families Type Structure
DNP-BIM-PP ACHE Derivative of Donepezil Multitarget Benzimidazole Metal ion chelator
RIV-BIM-4d ACHE Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Benzimidazole
TAC-BIM-11d ACHE Derivative of Tacrine Acridine Benzimidazole Carboxamide Multitarget anti-Abeta-aggregation
CHEMBL4561138 Epoxide_hydrolase Benzimidazole Sulfur Compound
75J-34n DPP4N_Peptidase_S9 Piperidine Imidazole Purine Cyanide
Retagliptin DPP4N_Peptidase_S9 Drug Gliptin Triazol Trifluoro Pro-Drug Imidazole
SCHEMBL20516363 ABHD6-Lip PAF-Acetylhydrolase Piperazine Imidazole Carbamate Morpholine
MJN193 ABHD6-Lip Piperazine Imidazole Carbamate
Desthiobiotin-PEG3-Azide Carbon-carbon_bond_hydrolase Azido ABPP-Probe Biotin derivative Imidazole
Butoxy-methyl-oxadiazol-aniline-4a ACHE Benzimidazole Oxadiazol
Benzimidazole-Diethylcarbamoyl-isopentyl-dimethylcarbamate-15d BCHE Cannabinoid-Receptor-ligand Benzimidazole Carbamate Carboxamide Multitarget
Benzimidazole-Ethoxybenzyl-isopentyl-azetidine-carboxylate-21d BCHE Cannabinoid-Receptor-ligand Benzimidazole Carbamate Carboxamide Multitarget Azetidin
Benzimidazole-phenyl-azetidine-carboxylate-11d BCHE Cannabinoid-Receptor-ligand Benzimidazole Carbamate Carboxamide Multitarget Azetidin
Cpd20-Benzimidazol-Oxadiazol BCHE Benzimidazole Oxadiazol Cyanide Carboxamide
S16-1029 BCHE Benzimidazole Oxadiazol Morpholine Carboxamide
Fragment-934 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzimidazole
Fragment-065 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzimidazole
Fragment-154 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzimidazole Cyanide
Fragment-173 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzimidazole Cyanide
CHEMBL3233605-S0D-3WK7 Epoxide_hydrolase Benzimidazole Pyrazole
S06-1011 BCHE Quinoline Imidazole Oxadiazol Benzimidazole
8012-9656 BCHE Quinoline Imidazole Oxadiazol Benzimidazole
RIV-BIMb-5d BCHE Derivative of Rivastigmine Carbamate Benzimidazole
BIA-10-2474 Carb_B_Chordata ABHD6-Lip Pyridine Imidazole FAAH inhibitor Multitarget Carboxamide
Histidine Hydroxynitrile_lyase Peptide Imidazole
Piperidine-fused-benzimidazole-25 DPP4N_Peptidase_S9 Trifluoro Piperidine Sulfur Compound Imidazole Benzimidazole Sulfonyl
Piperidine-fused-benzimidazole-34 DPP4N_Peptidase_S9 Trifluoro Piperidine Benzimidazole
R-Pro-(decarboxy-Pro)-X97 S9N_PPCE_Peptidase_S9 Pyrrolidine Imidazole
Benzimidazole-derivative-2 DPP4N_Peptidase_S9 Cyanide Imidazole Benzimidazole
5ALI-Q3B Epoxide_hydrolase Urea derivative Pyrimidine Imidazole Sulfur Compound
LIR DPP4N_Peptidase_S9 Cyanide Piperidine Imidazole
CB1R-ACHE-20 ACHE Multitarget Cannabinoid-Receptor-ligand Derivative of Tacrine Imidazole Carboxamide Alkyl linked bis-ligand
CB2R-BCHE-x BCHE Multitarget Cannabinoid-Receptor-ligand Piperidine Imidazole Carboxamide
CB2R-BCHE-20a BCHE Multitarget Cannabinoid-Receptor-ligand Piperidine Imidazole Carboxamide
CHEMBL1684295 Prolylcarboxypeptidase Pyrrolidine Imidazole Pyridine Oxadiazol Piperidine Benzimidazole
UCI-80224067 Prolylcarboxypeptidase Pyrrolidine Imidazole Benzimidazole
SZC Epoxide_hydrolase Sulfur Compound Sulfonamide Trifluoro Imidazole Benzimidazole
Ulosantoin ACHE Organophosphate Natural Imidazole
VX-Biotin Carboxypeptidase_S10 ACHE BCHE A85-EsteraseD-FGH ACPH_Peptidase_S9 Carb_B_Chordata Hormone-sensitive_lipase_like LYsophospholipase_carboxylesterase Lipase_3 Monoglyceridelipase_lysophospholip Arylacetamide_deacetylase Thioesterase DPP4N_Peptidase_S9 PC-sterol_acyltransferase ABHD6-Lip PAF-Acetylhydrolase S9N_PREPL_Peptidase_S9 PPase_methylesterase_euk Kynurenine-formamidase Organophosphate ABPP-Probe Imidazole Sulfur Compound Biotin derivative Derivative of VX
FP-Biotin Organophosphate ABPP-Probe Imidazole Sulfur Compound Biotin derivative
FP-Desthiobiotin LIDHydrolase Organophosphate ABPP-Probe Biotin derivative Imidazole
MSPI ACHE BCHE Organophosphate Imidazole Sulfur Compound
Guanitoxin ACHE Natural Organophosphate Imidazole
Benomyl ACHE Carbamate Fungicide Imidazole Benzimidazole
CHEMBL4456083 BCHE Derivative of Tacrine Alkyl linked bis-ligand Acridine Benzimidazole Carboxamide
KW-5092 ACHE Piperidine Imidazole
ParazoanthoxanthinA ACHE Natural Imidazole
Pseudozoanthoxanthin-like ACHE Natural Imidazole