Diallyl-disulfide

Diallyl sulfide is a natural product found in Allium (Garlic)

General

Type : Natural, Sulfur Compound

Chemical_Nomenclature : 3-(prop-2-enyldisulfanyl)prop-1-ene

Canonical SMILES : C=CCSSCC=C

InChI : InChI=1S\/C6H10S2\/c1-3-5-7-8-6-4-2\/h3-4H,1-2,5-6H2

InChIKey : PFRGXCVKLLPLIP-UHFFFAOYSA-N

Other name(s) : DADS  ||  Diallyl disulfide  ||  Allyl disulfide  ||  Diallyldisulfide  ||  Diallyl disulphide  ||  CHEBI:4488  ||  CHEMBL366603  ||  SCHEMBL93944


MW : 146.3

Formula : C6H10S2

CAS_number : 2179-57-9

PubChem : 16590

UniChem : PFRGXCVKLLPLIP-UHFFFAOYSA-N

Target

References (5)

Title : Mechanism of active acetylcholinesterase inhibition by organic sulfanes in garlic: Non-covalent binding and covalent modifications - Zhu_2023_Int.J.Biol.Macromol__124972
Author(s) : Zhu Y , Shi D , Chen A , Wang Y , Liu L , Bai B
Ref : Int J Biol Macromol , :124972 , 2023
Abstract :
PubMedSearch : Zhu_2023_Int.J.Biol.Macromol__124972
PubMedID: 37285891

Title : DADS Analogues Ameliorated the Cognitive Impairments of Alzheimer-Like Rat Model Induced by Scopolamine - Manral_2016_Neurotox.Res_30_407
Author(s) : Manral A , Meena P , Saini V , Siraj F , Shalini S , Tiwari M
Ref : Neurotox Res , 30 :407 , 2016
Abstract :
PubMedSearch : Manral_2016_Neurotox.Res_30_407
PubMedID: 27149969

Title : Multifunctional novel Diallyl disulfide (DADS) derivatives with beta-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease - Manral_2015_Bioorg.Med.Chem_23_6389
Author(s) : Manral A , Saini V , Meena P , Tiwari M
Ref : Bioorganic & Medicinal Chemistry , 23 :6389 , 2015
Abstract :
PubMedSearch : Manral_2015_Bioorg.Med.Chem_23_6389
PubMedID: 26337018

Title : Differential induction of hepatic microsomal epoxide hydrolase by alkyl sulphides and alkyl ethers in rat - Cho_1997_Xenobiotica_27_759
Author(s) : Cho JY , Kim SG
Ref : Xenobiotica , 27 :759 , 1997
Abstract :
PubMedSearch : Cho_1997_Xenobiotica_27_759
PubMedID: 9293614

Title : Differential effects of dietary diallyl sulfide and diallyl disulfide on rat intestinal and hepatic drug-metabolizing enzymes - Haber_1995_J.Toxicol.Environ.Health_44_423
Author(s) : Haber D , Siess MH , Canivenc-Lavier MC , Le Bon AM , Suschetet M
Ref : J Toxicol Environ Health , 44 :423 , 1995
Abstract :
PubMedSearch : Haber_1995_J.Toxicol.Environ.Health_44_423
PubMedID: 7723075