EDMM

Similar to VX

General

Type : Organophosphate, Sulfur Compound, Organothiophosphate, Nerve Agent V-series

Chemical_Nomenclature : O-ethyl S-(2-dimethylaminoethyl) methyl phosphonothioate

Canonical SMILES : CCOP(=O)(C)SCCN(C)C

InChI : InChI=1S\/C7H18NO2PS\/c1-5-10-11(4,9)12-7-6-8(2)3\/h5-7H2,1-4H3

InChIKey : PKDYQTANBZBIRM-UHFFFAOYSA-N

Other name(s) : Medemo, 25 SN, 33 SN, NISTC20820808, BRN 1769425, O-Ethyl S-2-dimethylaminoethyl methylphosphonothiolate, 4-04-00-03519, S-[2-(Dimethylamino)ethyl] o-ethyl methylphosphonothioate, O-Ethyl-S-(2-dimethylaminoethyl)-methylphosphonothioate, O-Aethyl-S-(2-dimethylaminoaethyl)-methylphosphonothioat


MW : 211.26

Formula : C7H18NO2PS

CAS_number : 20820-80-8

PubChem : 102302

UniChem : PKDYQTANBZBIRM-UHFFFAOYSA-N

Target

Families : EDMM ligand of proteins in family
ACHE

References (11)

Title : The influence of inhibitors and other factors on cholinesterases - Bajgar_1991_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_34_5
Author(s) : Bajgar J
Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 34 :5 , 1991
PubMedID: 1759111

Title : Inhibition of multiple molecular forms of human brain acetylcholinesterase by different types of inhibitors - Bajgar_1989_Sb.Ved.Pr.Lek.Fak.Karlovy.Univerzity.Hradci.Kralove_32_425
Author(s) : Bajgar J , Mate L
Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 32 :425 , 1989
PubMedID: 2637489

Title : Anticholinergic action of cholinesterase reactivator methoxime (bis-\/4- hydroxyaminomethylpyridinium\/-methane dichloride) -
Author(s) : Jakl A , Fusek J , Bajgar J
Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 29 :457 , 1986
PubMedID: 3481651

Title : Some possibilities of protection against acetylcholinesterase inhibition by organophosphates in vivo -
Author(s) : Bajgar J , Patocka J , Fusek J , Hrdina V
Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 27 :425 , 1984
PubMedID: 6599819

Title : The influence of some drugs on the rat blood phosphodiesterase activity -
Author(s) : Bajgar J , Fusek J , Patocka J , Hrdina V
Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 26 :423 , 1983
PubMedID: 6100335

Title : Protective effect of 9-amino-7-methoxy-1,2,3,4-tetra-hydroacridine against inhibition of acetylcholinesterase by O-ethyl s-(2- dimethylaminoethyl) methylphosphonotioate in vivo -
Author(s) : Bajgar J , Fusek J , Patocka J , Hrdina V
Ref : Archives of Toxicology , 54 :163 , 1983
PubMedID: 6651529

Title : [Therapy of domestic animals affected by alkylphosphates] - Benes_1979_Vet.Med_24_623
Author(s) : Benes J , Hrusovsky J , Proksova M
Ref : Vet Med , 24 :623 , 1979
PubMedID: 117593

Title : Actions of O-ethyl-S-(2-dimethylaminoethyl)-methylphosphonothioate and some pyridine aldoximes on isolated guinea-pigs heart atria - Fusek_1978_Acta.Biol.Med.Ger_37_347
Author(s) : Fusek J , Patocka J , Bajgar J
Ref : Acta Biologica et Medica Germanica , 37 :347 , 1978
PubMedID: 706945

Title : [Therapy of organophosphate poisoning in animals] - Benes_1976_Vet.Med_21_343
Author(s) : Benes J , Proksova M , Hrusovsky J
Ref : Vet Med , 21 :343 , 1976
PubMedID: 826002

Title : [Antidotal effect of TMB-4(Trimedoxime) compos. Spofa in sheep intoxicated with O-ethyl S-(2-dimethylaminoethyl) methyl phosphonothioate]. [Czech] - Benes_1976_Vet.Med_21_237
Author(s) : Benes J , Proksova M , Hrusovsky J
Ref : Veterinarni Medicina , 21 :237 , 1976
PubMedID: 824781

Title : [Reactivating effect of trimedoxime and obidoxime on cholinesterases inhibited in the heart and intercostal muscles of the rat during acute poisoning with O-ethyl-S-(dimethylaminethyl)-methylthiophosphonate. (A histochemical study)]. [Czech] -
Author(s) : Picha B
Ref : Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove , 17 :195 , 1974
PubMedID: 4620479