Isocarbophos
Carboxylesterase was found to be responsible for the hydrolysis of ICP Zhang 2014
General
Type : Organophosphate, Benzoate, Sulfur Compound
Chemical_Nomenclature : propan-2-yl 2-[amino(methoxy)phosphinothioyl]oxybenzoate
Canonical SMILES : CC(C)OC(=O)C1=CC=CC=C1OP(=S)(N)OC
InChI : InChI=1S\/C11H16NO4PS\/c1-8(2)15-11(13)9-6-4-5-7-10(9)16-17(12,18)14-3\/h4-8H,1-3H3,(H2,12,18)
InChIKey : YFVOXLJXJBQDEF-UHFFFAOYSA-N
Other name(s) : Optunal || Caswell No. 574B || Isopropyl 2-((aminomethoxyphosphinothioyl)oxy)benzoate || Bay 93820 || CHEBI:38704
MW : 289.28
Formula : C11H16NO4PS
CAS_number : 24353-61-5
PubChem : 90479
UniChem : YFVOXLJXJBQDEF-UHFFFAOYSA-N
Target
Families : Isocarbophos ligand of proteins in family
ACHE
References (12)
| Title : A potential biomarker of isofenphos-methyl in humans: A chiral view - Gao_2019_Environ.Int_127_694 |
| Author(s) : Gao B , Zhao S , Zhang Z , Li L , Hu K , Kaziem AE , He Z , Hua X , Shi H , Wang M |
| Ref : Environ Int , 127 :694 , 2019 |
| Abstract : |
| PubMedSearch : Gao_2019_Environ.Int_127_694 |
| PubMedID: 30991225 |
| Title : Bioaccumulation of isocarbophos enantiomers from laboratory-contaminated aquatic environment by tubificid worms - Liu_2015_Chemosphere_124_77 |
| Author(s) : Liu T , Diao J , Di S , Zhou Z |
| Ref : Chemosphere , 124 :77 , 2015 |
| Abstract : |
| PubMedSearch : Liu_2015_Chemosphere_124_77 |
| PubMedID: 25475969 |
| Title : Simultaneous enantioselective determination of isocarbophos and its main metabolite isocarbophos oxon in rice, soil, and water by chiral liquid chromatography and tandem mass spectrometry - Yao_2015_J.Sep.Sci_38_1663 |
| Author(s) : Yao Z , Lin M , Xu M , Wang T , Ping X , Wu S , Wang Q , Zhang H |
| Ref : J Sep Sci , 38 :1663 , 2015 |
| Abstract : |
| PubMedSearch : Yao_2015_J.Sep.Sci_38_1663 |
| PubMedID: 25755196 |
| Title : Contribution of carboxylesterase and cytochrome p450 to the bioactivation and detoxification of isocarbophos and its enantiomers in human liver microsomes - Zhuang_2014_Toxicol.Sci_140_40 |
| Author(s) : Zhuang XM , Wei X , Tan Y , Xiao WB , Yang HY , Xie JW , Lu C , Li H |
| Ref : Toxicol Sci , 140 :40 , 2014 |
| Abstract : |
| PubMedSearch : Zhuang_2014_Toxicol.Sci_140_40 |
| PubMedID: 24752505 |
| Title : Biophysical influence of isocarbophos on bovine serum albumin: spectroscopic probing - Zhang_2012_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_92_283 |
| Author(s) : Zhang HX , Zhou Y , Liu E |
| Ref : Spectrochim Acta A Mol Biomol Spectrosc , 92 :283 , 2012 |
| Abstract : |
| PubMedSearch : Zhang_2012_Spectrochim.Acta.A.Mol.Biomol.Spectrosc_92_283 |
| PubMedID: 22446777 |
| Title : Enantioselective toxicological response of the green alga Scenedesmus obliquus to isocarbophos - Lu_2012_Chirality_24_481 |
| Author(s) : Lu D , Huang L , Diao J , Zhou Z |
| Ref : Chirality , 24 :481 , 2012 |
| Abstract : |
| PubMedSearch : Lu_2012_Chirality_24_481 |
| PubMedID: 22544637 |
| Title : Enantioselective cytotoxicity of isocarbophos is mediated by oxidative stress-induced JNK activation in human hepatocytes - Liu_2010_Toxicology_276_115 |
| Author(s) : Liu H , Liu J , Xu L , Zhou S , Li L , Liu W |
| Ref : Toxicology , 276 :115 , 2010 |
| Abstract : |
| PubMedSearch : Liu_2010_Toxicology_276_115 |
| PubMedID: 20688129 |
| Title : Isolation of an isocarbophos-degrading strain of Arthrobacter sp. scl-2 and identification of the degradation pathway - Rong_2009_J.Microbiol.Biotechnol_19_1439 |
| Author(s) : Rong L , Guo X , Chen K , Zhu J , Li S , Jiang J |
| Ref : J Microbiol Biotechnol , 19 :1439 , 2009 |
| Abstract : |
| PubMedSearch : Rong_2009_J.Microbiol.Biotechnol_19_1439 |
| PubMedID: 19996699 |
| Title : Single and joint acute toxicity of isocarbophos enantiomers to Daphnia magna - Lin_2008_J.Agric.Food.Chem_56_4273 |
| Author(s) : Lin K , Liu W , Li L , Gan J |
| Ref : Journal of Agricultural and Food Chemistry , 56 :4273 , 2008 |
| Abstract : |
| PubMedSearch : Lin_2008_J.Agric.Food.Chem_56_4273 |
| PubMedID: 18489111 |
| Title : [Effect of HuperzineA on neurophathologic change of mouse exposed by isocarbophos and phoxim] - Xie_2006_Wei.Sheng.Yan.Jiu_35_339 |
| Author(s) : Xie GY , Liu L , Wang J , Zhao WJ |
| Ref : Wei Sheng Yan Jiu , 35 :339 , 2006 |
| Abstract : |
| PubMedSearch : Xie_2006_Wei.Sheng.Yan.Jiu_35_339 |
| PubMedID: 16921763 |
| Title : Effect of alcohols and temperature on the direct chiral resolutions of fipronil, isocarbophos and carfentrazone-ethyl - Wang_2005_Biomed.Chromatogr_19_454 |
| Author(s) : Wang P , Jiang S , Liu D , Jia G , Wang Q , Zhou Z |
| Ref : Biomedical Chromatography , 19 :454 , 2005 |
| Abstract : |
| PubMedSearch : Wang_2005_Biomed.Chromatogr_19_454 |
| PubMedID: 16037928 |
| Title : [The neuromuscular transmission effects induced by pralidoxine chloride on rats with acute isocarbophos poisoning] - Ju_2002_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_20_425 |
| Author(s) : Ju Z , Sun J |
| Ref : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi , 20 :425 , 2002 |
| Abstract : |
| PubMedSearch : Ju_2002_Zhonghua.Lao.Dong.Wei.Sheng.Zhi.Ye.Bing.Za.Zhi_20_425 |
| PubMedID: 14694590 |