Title : Radiosynthesis and evaluation of novel (18)F labeled PET ligands for imaging monoacylglycerol lipase - Li_2025_Eur.J.Med.Chem_285_117246 |
Author(s) : Li Y , Mori W , Chaudhary A , Zhao C , Yamasaki T , Zhang Z , Feng S , Ware T , Rong J , Fujinaga M , Chen J , Kumata K , Zhang Y , Hu K , Xie L , Zhou X , Song Z , Gao Y , Sun Z , Patel JS , Zhai C , Yuan KY , Collier TL , Ran C , Collin L , Haider A , Grether U , Wittwer MB , Cravatt BF , Zhang MR , Liang SH |
Ref : Eur Journal of Medicinal Chemistry , 285 :117246 , 2025 |
Abstract : |
PubMedSearch : Li_2025_Eur.J.Med.Chem_285_117246 |
PubMedID: 39793441 |
Gene_locus related to this paper: human-MGLL |
Title : Synthesis and preclinical evaluation of novel (18)F-labeled fibroblast activation protein tracers for positron emission tomography imaging of cancer-associated fibroblasts - Zhou_2024_Eur.J.Med.Chem_264_115993 |
Author(s) : Zhou H , Zhong J , Peng S , Liu Y , Tang P , Cai Z , Wang L , Xu H , Hu K |
Ref : Eur Journal of Medicinal Chemistry , 264 :115993 , 2024 |
Abstract : |
PubMedSearch : Zhou_2024_Eur.J.Med.Chem_264_115993 |
PubMedID: 38039792 |
Title : Fe(3)O(4)@MXene@PEI aerogel immobilized acetylcholinesterase for inhibitor screening from herbal plants - Zhao_2024_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1247_124345 |
Author(s) : Zhao D , Li Z , Liu X , Zhang Z , Ma H , Wang P , Song J , Hu K |
Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 1247 :124345 , 2024 |
Abstract : |
PubMedSearch : Zhao_2024_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1247_124345 |
PubMedID: 39490207 |
Title : Beyond Small Molecules: Antibodies and Peptides for Fibroblast Activation Protein Targeting Radiopharmaceuticals - Sun_2024_Pharmaceutics_16_ |
Author(s) : Sun X , Wu Y , Wang X , Gao X , Zhang S , Sun Z , Liu R , Hu K |
Ref : Pharmaceutics , 16 : , 2024 |
Abstract : |
PubMedSearch : Sun_2024_Pharmaceutics_16_ |
PubMedID: 38543239 |
Gene_locus related to this paper: human-FAP |
Title : Comprehensive Analysis of Fibroblast Activation Protein Expression in Interstitial Lung Diseases - Yang_2023_Am.J.Respir.Crit.Care.Med_207_160 |
Author(s) : Yang P , Luo Q , Wang X , Fang Q , Fu Z , Li J , Lai Y , Chen X , Xu X , Peng X , Hu K , Nie X , Liu S , Zhang J , Shen C , Gu Y , Liu J , Chen J , Zhong N , Su J |
Ref : American Journal of Respiratory & Critical Care Medicine , 207 :160 , 2023 |
Abstract : |
PubMedSearch : Yang_2023_Am.J.Respir.Crit.Care.Med_207_160 |
PubMedID: 35984444 |
Gene_locus related to this paper: human-FAP |
Title : Noninvasive imaging of FAP expression using positron emission tomography: A comparative evaluation of a [(18)F]-labeled glycopeptide-containing FAPI with [(18)F]FAPI-42 - Huang_2023_Eur.J.Nucl.Med.Mol.Imaging_50_3363 |
Author(s) : Huang J , Fu L , Zhang X , Huang S , Dong Y , Hu K , Han Y , Zhou K , Min C , Huang Y , Tang G |
Ref : Eur J Nucl Med Mol Imaging , 50 :3363 , 2023 |
Abstract : |
PubMedSearch : Huang_2023_Eur.J.Nucl.Med.Mol.Imaging_50_3363 |
PubMedID: 37266596 |
Title : A novel cold-adapted pyrethroid-degrading esterase from Bacillus subtilis J6 and its application for pyrethroid-residual alleviation in food matrix - Zhang_2023_J.Hazard.Mater_463_132847 |
Author(s) : Zhang M , Yang K , Yang L , Diao Y , Wang X , Hu K , Li Q , Li J , Zhao N , He L , Chen S , Liu A , Ao X , Yang Y , Liu S |
Ref : J Hazard Mater , 463 :132847 , 2023 |
Abstract : |
PubMedSearch : Zhang_2023_J.Hazard.Mater_463_132847 |
PubMedID: 39491987 |
Title : Radiosynthesis, preclinical evaluation and pilot clinical PET imaging study of a (18)F-labeled tracer targeting fibroblast activation protein - Fu_2023_Bioorg.Chem_141_106878 |
Author(s) : Fu L , Huang J , Liu Q , Xie F , Han Y , Sun P , Cao M , Huang Y , Hu K , Tang G |
Ref : Bioorg Chem , 141 :106878 , 2023 |
Abstract : |
PubMedSearch : Fu_2023_Bioorg.Chem_141_106878 |
PubMedID: 37774434 |
Gene_locus related to this paper: human-FAP |
Title : Comparison of (68)Ga-FAPI and (18)F-FDG PET\/CT in the Evaluation of Advanced Lung Cancer - Wang_2022_Radiology_303_191 |
Author(s) : Wang L , Tang G , Hu K , Liu X , Zhou W , Li H , Huang S , Han Y , Chen L , Zhong J , Wu H |
Ref : Radiology , 303 :191 , 2022 |
Abstract : |
PubMedSearch : Wang_2022_Radiology_303_191 |
PubMedID: 34981976 |
Title : Semaglutide May Alleviate Hepatic Steatosis in T2DM Combined with NFALD Mice via miR-5120\/ABHD6 - Li_2022_Drug.Des.Devel.Ther_16_3557 |
Author(s) : Li R , Ye Z , She D , Fang P , Zong G , Hu K , Kong D , Xu W , Li L , Zhou Y , Zhang K , Xue Y |
Ref : Drug Des Devel Ther , 16 :3557 , 2022 |
Abstract : |
PubMedSearch : Li_2022_Drug.Des.Devel.Ther_16_3557 |
PubMedID: 36238196 |
Title : [(18)F]FAPI-42 PET imaging in cancer patients: optimal acquisition time, biodistribution, and comparison with [(68)Ga]Ga-FAPI-04 - Hu_2022_Eur.J.Nucl.Med.Mol.Imaging_49_2833 |
Author(s) : Hu K , Wang L , Wu H , Huang S , Tian Y , Wang Q , Xiao C , Han Y , Tang G |
Ref : Eur J Nucl Med Mol Imaging , 49 :2833 , 2022 |
Abstract : |
PubMedSearch : Hu_2022_Eur.J.Nucl.Med.Mol.Imaging_49_2833 |
PubMedID: 34893920 |
Title : Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold - Rong_2021_J.Med.Chem__ |
Author(s) : Rong J , Mori W , Xia X , Schafroth MA , Zhao C , Van RS , Yamasaki T , Chen J , Xiao Z , Haider A , Ogasawara D , Hiraishi A , Shao T , Zhang Y , Chen Z , Pang F , Hu K , Xie L , Fujinaga M , Kumata K , Gou Y , Fang Y , Gu S , Wei H , Bao L , Xu H , Collier TL , Shao Y , Carson RE , Cravatt BF , Wang L , Zhang MR , Liang SH |
Ref : Journal of Medicinal Chemistry , : , 2021 |
Abstract : |
PubMedSearch : Rong_2021_J.Med.Chem__ |
PubMedID: 34569803 |
Gene_locus related to this paper: human-MGLL |
Title : Current insights into the microbial degradation for pyrethroids: strain safety, biochemical pathway, and genetic engineering - Zhao_2021_Chemosphere_279_130542 |
Author(s) : Zhao T , Hu K , Li J , Zhu Y , Liu A , Yao K , Liu S |
Ref : Chemosphere , 279 :130542 , 2021 |
Abstract : |
PubMedSearch : Zhao_2021_Chemosphere_279_130542 |
PubMedID: 33866100 |
Title : Development of a highly-specific (18)F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping - Chen_2021_Acta.Pharm.Sin.B_11_1686 |
Author(s) : Chen Z , Mori W , Rong J , Schafroth MA , Shao T , Van RS , Ogasawara D , Yamasaki T , Hiraishi A , Hatori A , Chen J , Zhang Y , Hu K , Fujinaga M , Sun J , Yu Q , Collier TL , Shao Y , Cravatt BF , Josephson L , Zhang MR , Liang SH |
Ref : Acta Pharm Sin B , 11 :1686 , 2021 |
Abstract : |
PubMedSearch : Chen_2021_Acta.Pharm.Sin.B_11_1686 |
PubMedID: 34221877 |
Gene_locus related to this paper: human-MGLL |
Title : Safety and efficacy assessment of allogeneic human dental pulp stem cells to treat patients with severe COVID-19: structured summary of a study protocol for a randomized controlled trial (Phase I \/ II) - Ye_2020_Trials_21_520 |
Author(s) : Ye Q , Wang H , Xia X , Zhou C , Liu Z , Xia ZE , Zhang Z , Zhao Y , Yehenala J , Wang S , Zhou G , Hu K , Wu B , Wu CT , He Y |
Ref : Trials , 21 :520 , 2020 |
Abstract : |
PubMedSearch : Ye_2020_Trials_21_520 |
PubMedID: 32532356 |
Title : Serum Cholinesterases, a Novel Marker of Clinical Activity in Inflammatory Bowel Disease: A Retrospective Case-Control Study - Shao_2020_Mediators.Inflamm_2020_4694090 |
Author(s) : Shao X , Yang L , Hu K , Shen R , Ye Q , Yuan X , Zhao Q , Shen J |
Ref : Mediators Inflamm , 2020 :4694090 , 2020 |
Abstract : |
PubMedSearch : Shao_2020_Mediators.Inflamm_2020_4694090 |
PubMedID: 32733165 |
Title : Positive correlation between human exposure to organophosphate esters and gastrointestinal cancer in patients from Wuhan, China - Li_2020_Ecotoxicol.Environ.Saf_196_110548 |
Author(s) : Li Y , Fu Y , Hu K , Zhang Y , Chen J , Zhang S , Zhang B , Liu Y |
Ref : Ecotoxicology & Environmental Safety , 196 :110548 , 2020 |
Abstract : |
PubMedSearch : Li_2020_Ecotoxicol.Environ.Saf_196_110548 |
PubMedID: 32278140 |
Title : Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity - Ramachandran_2019_Dev.Cell_48_685 |
Author(s) : Ramachandran PV , Savini M , Folick AK , Hu K , Masand R , Graham BH , Wang MC |
Ref : Dev Cell , 48 :685 , 2019 |
Abstract : |
PubMedSearch : Ramachandran_2019_Dev.Cell_48_685 |
PubMedID: 30713071 |
Gene_locus related to this paper: caeel-K04A8.5 |
Title : Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[(11)C]carboxylate - Mori_2019_Bioorg.Med.Chem_27_3568 |
Author(s) : Mori W , Hatori A , Zhang Y , Kurihara Y , Yamasaki T , Xie L , Kumata K , Hu K , Fujinaga M , Zhang MR |
Ref : Bioorganic & Medicinal Chemistry , 27 :3568 , 2019 |
Abstract : |
PubMedSearch : Mori_2019_Bioorg.Med.Chem_27_3568 |
PubMedID: 31278005 |
Title : A potential biomarker of isofenphos-methyl in humans: A chiral view - Gao_2019_Environ.Int_127_694 |
Author(s) : Gao B , Zhao S , Zhang Z , Li L , Hu K , Kaziem AE , He Z , Hua X , Shi H , Wang M |
Ref : Environ Int , 127 :694 , 2019 |
Abstract : |
PubMedSearch : Gao_2019_Environ.Int_127_694 |
PubMedID: 30991225 |
Title : Identification of Carassius auratus gibelio liver cell proteins interacting with the GABAA receptor gamma2 subunit using a yeast two-hybrid system - Ma_2019_Fish.Physiol.Biochem_45_199 |
Author(s) : Ma RR , Sun J , Fang WH , Dong YP , Ruan JM , Yang XL , Hu K |
Ref : Fish Physiol Biochem , 45 :199 , 2019 |
Abstract : |
PubMedSearch : Ma_2019_Fish.Physiol.Biochem_45_199 |
PubMedID: 30242696 |
Title : Design, Synthesis, and Evaluation of (18)F-Labeled Monoacylglycerol Lipase Inhibitors as Novel Positron Emission Tomography Probes - Chen_2019_J.Med.Chem_62_8866 |
Author(s) : Chen Z , Mori W , Fu H , Schafroth MA , Hatori A , Shao T , Zhang G , Van RS , Zhang Y , Hu K , Fujinaga M , Wang L , Belov V , Ogasawara D , Giffenig P , Deng X , Rong J , Yu Q , Zhang X , Papisov MI , Shao Y , Collier TL , Ma JA , Cravatt BF , Josephson L , Zhang MR , Liang SH |
Ref : Journal of Medicinal Chemistry , 62 :8866 , 2019 |
Abstract : |
PubMedSearch : Chen_2019_J.Med.Chem_62_8866 |
PubMedID: 31518130 |
Title : Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a Tail Switching Strategy on a Piperazinyl Azetidine Skeleton - Chen_2019_J.Med.Chem_62_3336 |
Author(s) : Chen Z , Mori W , Deng X , Cheng R , Ogasawara D , Zhang G , Schafroth MA , Dahl K , Fu H , Hatori A , Shao T , Zhang Y , Yamasaki T , Zhang X , Rong J , Yu Q , Hu K , Fujinaga M , Xie L , Kumata K , Gou Y , Chen J , Gu S , Bao L , Wang L , Collier TL , Vasdev N , Shao Y , Ma JA , Cravatt BF , Fowler C , Josephson L , Zhang MR , Liang SH |
Ref : Journal of Medicinal Chemistry , 62 :3336 , 2019 |
Abstract : |
PubMedSearch : Chen_2019_J.Med.Chem_62_3336 |
PubMedID: 30829483 |
Gene_locus related to this paper: human-MGLL |
Title : Transcriptional responses in the hepatopancreas of Eriocheir sinensis exposed to deltamethrin - Yang_2017_PLoS.One_12_e0184581 |
Author(s) : Yang Z , Zhang Y , Jiang Y , Zhu F , Zeng L , Wang Y , Lei X , Yao Y , Hou Y , Xu L , Xiong C , Yang X , Hu K |
Ref : PLoS ONE , 12 :e0184581 , 2017 |
Abstract : |
PubMedSearch : Yang_2017_PLoS.One_12_e0184581 |
PubMedID: 28910412 |
Title : Ameliorative effect of lotus seedpod proanthocyanidins on cognitive impairment and brain aging induced by d-galactose - Gong_2016_Exp.Gerontol_74_21 |
Author(s) : Gong YS , Guo J , Hu K , Gao YQ , Xie BJ , Sun ZD , Yang EN , Hou FL |
Ref : Experimental Gerontology , 74 :21 , 2016 |
Abstract : |
PubMedSearch : Gong_2016_Exp.Gerontol_74_21 |
PubMedID: 26657492 |
Title : Design, synthesis and evaluation of novel ferulic acid-memoquin hybrids as potential multifunctional agents for the treatment of Alzheimer's disease - Pan_2016_Bioorg.Med.Chem.Lett_26_2539 |
Author(s) : Pan W , Hu K , Bai P , Yu L , Ma Q , Li T , Zhang X , Chen C , Peng K , Liu W , Sang Z |
Ref : Bioorganic & Medicinal Chemistry Lett , 26 :2539 , 2016 |
Abstract : |
PubMedSearch : Pan_2016_Bioorg.Med.Chem.Lett_26_2539 |
PubMedID: 27072909 |
Title : Solvent-free enzymatic synthesis of 1, 3-diacylglycerols by direct esterification of glycerol with saturated fatty acids - Zhong_2013_Lipids.Health.Dis_12_65 |
Author(s) : Zhong N , Gui Z , Xu L , Huang J , Hu K , Gao Y , Zhang X , Xu Z , Su J , Li B |
Ref : Lipids Health Dis , 12 :65 , 2013 |
Abstract : |
PubMedSearch : Zhong_2013_Lipids.Health.Dis_12_65 |
PubMedID: 23656739 |
Title : Activation and allosteric modulation of a muscarinic acetylcholine receptor - Kruse_2013_Nature_504_101 |
Author(s) : Kruse AC , Ring AM , Manglik A , Hu J , Hu K , Eitel K , Hubner H , Pardon E , Valant C , Sexton PM , Christopoulos A , Felder CC , Gmeiner P , Steyaert J , Weis WI , Garcia KC , Wess J , Kobilka BK |
Ref : Nature , 504 :101 , 2013 |
Abstract : |
PubMedSearch : Kruse_2013_Nature_504_101 |
PubMedID: 24256733 |
Title : Muscarinic receptors as model targets and antitargets for structure-based ligand discovery - Kruse_2013_Mol.Pharmacol_84_528 |
Author(s) : Kruse AC , Weiss DR , Rossi M , Hu J , Hu K , Eitel K , Gmeiner P , Wess J , Kobilka BK , Shoichet BK |
Ref : Molecular Pharmacology , 84 :528 , 2013 |
Abstract : |
PubMedSearch : Kruse_2013_Mol.Pharmacol_84_528 |
PubMedID: 23887926 |