KBR-2822

KBR-2822 promotes OPIDP initiated by either DBDCVP or DFP by affecting a target other than NTE catalytic site

General

Type : Sulfur Compound, Organophosphate, Trifluoro, Not A\/B H target

Chemical_Nomenclature : 2-chloro-3-[ethoxy(propylsulfanyl)phosphoryl]oxy-1,1,2-trifluorocyclobutane

Canonical SMILES : CCCSP(=O)(OCC)OC1CC(C1(F)Cl)(F)F

InChI : InChI=1S\/C9H15ClF3O3PS\/c1-3-5-18-17(14,15-4-2)16-7-6-8(11,12)9(7,10)13\/h7H,3-6H2,1-2H3

InChIKey : DEMICWQHGWSYPB-UHFFFAOYSA-N

Other name(s) : phosphorothioic acid-O-(2-chloro-2,3,3-trifluorocyclobutyl)-O-ethyl S-propyl ester, KBR 2822, O-(2-Chloro-2,3,3-trifluorocyclobutyl) O-ethyl S-propyl phosphorothioate, Phosphorothioic acid, O-(2-chloro-2,3,3-trifluorocyclobutyl) O-ethyl S-propyl ester


MW : 326.70

Formula : C9H15ClF3O3PS

CAS_number : 126988-60-1

PubChem : 182779

UniChem : DEMICWQHGWSYPB-UHFFFAOYSA-N

Target

References (3)

Title : Promotion of organophosphate induced delayed polyneuropathy by certain esterase inhibitors - Lotti_2002_Toxicology_181-182_245
Author(s) : Lotti M
Ref : Toxicology , 181-182 :245 , 2002
PubMedID: 12505319

Title : Repeated low doses of O-(2-chloro-2,3,3 trifluorocyclobutyl) O-ethyl S- propyl phosphorothioate (KBR-2822) do not cause neuropathy in hens - Jokanovic_1998_Arch.Toxicol_72_93
Author(s) : Jokanovic M , Moretto A , Lotti M
Ref : Archives of Toxicology , 72 :93 , 1998
PubMedID: 9456080

Title : The phosphorothioic acid O-(2-chloro-2,3,3-trifluorocyclobutyl) O-ethyl S-propyl ester exacerbates organophosphate polyneuropathy without inhibition of neuropathy target esterase - Moretto_1994_Toxicol.Appl.Pharmacol_129_133
Author(s) : Moretto A , Bertolazzi M , Lotti M
Ref : Toxicol Appl Pharmacol , 129 :133 , 1994
PubMedID: 7974486