KC02

A negative control for KC01 the ABHD16A inhibitor IC50 > 10microM could be a relatively good inhibitor of ABHD11

General

Type : Oxooxetan

Chemical_Nomenclature : (6Z)-6-[2-oxo-4-(2-phenylethyl)oxetan-3-ylidene]hexanamide

Canonical SMILES : C1=CC=C(C=C1)CCC2C(=CCCCCC(=O)N)C(=O)O2

InChI : InChI=1S\/C17H21NO3\/c18-16(19)10-6-2-5-9-14-15(21-17(14)20)12-11-13-7-3-1-4-8-13\/h1,3-4,7-9,15H,2,5-6,10-12H2,(H2,18,19)\/b14-9-

InChIKey : XWRBNJBEHUJLPT-ZROIWOOFSA-N

Other name(s) : 6-(2-Oxo-4-phenethyloxetan-3-ylidene)hexanamide  ||  SCHEMBL17760841  ||  (Z)-6-(2-Oxo-4-phenethyloxetan-3-ylidene)hexanamide  ||  6Z-[2-oxo-4-(2-phenylethyl)-3-oxetanylidene],hexanamide


MW : 287.35

Formula : C17H21NO3

CAS_number : 1646795-60-9

PubChem : 86289034

UniChem : XWRBNJBEHUJLPT-ZROIWOOFSA-N

Target

References (1)

Title : Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay - Kamat_2015_Nat.Chem.Biol_11_164
Author(s) : Kamat SS , Camara K , Parsons WH , Chen DH , Dix MM , Bird TD , Howell AR , Cravatt BF
Ref : Nat Chemical Biology , 11 :164 , 2015
Abstract :
PubMedSearch : Kamat_2015_Nat.Chem.Biol_11_164
PubMedID: 25580854
Gene_locus related to this paper: human-ABHD12 , human-ABHD16A , mouse-abd12 , mouse-Abhd16a