mouse-abd12

Mus musculus (Mouse) abhydrolase domain-containing protein 12 protein c20orf22 CT022 (fragment)

Comment

Relationship

Family : ABHD12-PHARC

Block : X

Position in NCBI Life Tree : Mus musculus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Mus [genus] N E > Mus [subgenus] N E > Mus musculus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MRKRTEPVTL EHERCAASGS SSSGSAAAAL DADCSLKQNL RLAGKGTAEP HSASDAGMKR ALGRRKSLWF RLRKILLCVL GFYIAIPFLV KLCPGIQAKL IFLNFVRVPY FIDLKKPQDQ GLNHTCNYYL QPEDDVTIGV WHTIPSVWWK NAQGKDQMWY EDALASNHAI ILYLHGNAGT RGGDHRVELY KVLSSLGYHV VTFDYRGWGD SVGTPSERGM TYDALHVFDW IKARSGDNPV YIWGHSLGTG VATNLVRRLC ERETPPDALI LESPFTNIRE EAKSHPFSVI YRYFPGFDWF FLDPITSSGI KFANDENMKH ISCPLLILHA EDDPVVPFHL GRKLYNIAAP SRSFRDFKVQ FIPFHSDLGY RHKYIYKSPE LPRILREFLG KSEPERQH

References (5)

Title : The loss of enzymatic activity of the PHARC associated lipase ABHD12 results in increased phagocytosis that causes neuroinflammation - Singh_2021_Eur.J.Neurosci__
Author(s) : Singh S , Kamat SS
Ref : European Journal of Neuroscience , : , 2021
PubMedID: 34727579
Gene_locus related to this paper: human-ABHD12 , mouse-abd12

Title : Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype - Leishman_2019_Front.Mol.Neurosci_12_142
Author(s) : Leishman E , Mackie K , Bradshaw HB
Ref : Front Mol Neurosci , 12 :142 , 2019
PubMedID: 31213981
Gene_locus related to this paper: mouse-abd12

Title : Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay - Kamat_2015_Nat.Chem.Biol_11_164
Author(s) : Kamat SS , Camara K , Parsons WH , Chen DH , Dix MM , Bird TD , Howell AR , Cravatt BF
Ref : Nat Chemical Biology , 11 :164 , 2015
PubMedID: 25580854
Gene_locus related to this paper: human-ABHD12 , human-ABHD16A , mouse-abd12 , mouse-Abhd16a

Title : A tissue-specific atlas of mouse protein phosphorylation and expression - Huttlin_2010_Cell_143_1174
Author(s) : Huttlin EL , Jedrychowski MP , Elias JE , Goswami T , Rad R , Beausoleil SA , Villen J , Haas W , Sowa ME , Gygi SP
Ref : Cell , 143 :1174 , 2010
PubMedID: 21183079
Gene_locus related to this paper: mouse-abd12 , mouse-Ces2a , mouse-CMBL , mouse-ndr1 , mouse-ndr2 , mouse-ndr4 , mouse-f172a