Oxooxetan

General

Building block for many inhibitors of enzymes

Inhibitor	Main targeted enzyme familyes	Type
EZ120P	A85-Mycolyl-transferase	Oxooxetan Lipase inhibitor Alkyne
Cpd17-Pyrrolidine-THL-derivative	Cutinase	Oxooxetan Lipase inhibitor Pyrrolidine
EZ120	A85-Mycolyl-transferase	Oxooxetan Lipase inhibitor
Tetrahydrolipstatin-alkyne	Hormone-sensitive_lipase_like	Oxooxetan Lipase inhibitor Alkyne
KC02		Oxooxetan
KC01	Cholesterol_esterase ABHD16	Oxooxetan
L-Isoleucine-Orlistat	Lipase_3	Oxooxetan Lipase inhibitor
Palmostatin-M	LYsophospholipase_carboxylesterase ABHD17-depalmitoylase ABHD6-Lip S9N_PREPL_Peptidase_S9	Oxooxetan Sulfur Compound
Palmostatin-B	ABHD16 Thioesterase 5_AlphaBeta_hydrolase ABHD17-depalmitoylase ABHD6-Lip LYsophospholipase_carboxylesterase S9N_PREPL_Peptidase_S9	Oxooxetan
Ebelactone-A	Homoserine_transacetylase Pancreatic_lipase ACPH_Peptidase_S9	Oxooxetan Natural
Ebelactone-B	Cutinase Carboxypeptidase_S10 Hepatic_Lipase Lipoprotein_Lipase Pancreatic_lipase	Oxooxetan Natural
Esterastin	Acidic_Lipase Pancreatic_lipase	Oxooxetan Natural Lipase inhibitor
Panclicin-D	Pancreatic_lipase	Oxooxetan Natural
Valilactone	Pancreatic_lipase	Oxooxetan Natural
Lipstatin	Pancreatic_lipase	Oxooxetan Natural Lipase inhibitor
THL-10d	A85-Mycolyl-transferase	Oxooxetan Lipase inhibitor Benzyloxycarbonyl
Orlistat	AlphaBeta_hydrolase Acidic_Lipase Pancreatic_lipase Thioesterase Carb_B_Chordata ABHD6-Lip Lipase_3 Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip Cutinase ABHD16 A85-Mycolyl-transferase PE-PPE Plasmodium_subtelomeric_PST-A Bacterial_lip_FamI.6	Oxooxetan Lipase inhibitor