Oxooxetan

General

Building block for many inhibitors of enzymes

Inhibitor	Main targeted enzyme families	Type
3-benzyl-4-tridecyloxetan-2-one-trans5c	Carb_B_Chordata abh_upf0017 ABHD12-PHARC ABHD16 Thioesterase	Tridecyl Lactone Oxooxetan
EZ120P	A85-Mycolyl-transferase	Oxooxetan Lipase inhibitor Alkyne Propargyl
Cpd17-Pyrrolidine-THL-derivative	Cutinase	Oxooxetan Lipase inhibitor Pyrrolidine
EZ120	A85-Mycolyl-transferase	Oxooxetan Lipase inhibitor
Tetrahydrolipstatin-alkyne	Hormone-sensitive_lipase_like	Oxooxetan Lipase inhibitor Alkyne Propargyl
KC02		Oxooxetan
KC01	Cholesterol_esterase ABHD16	Oxooxetan Tridecyl
L-Isoleucine-Orlistat	Lipase_3	Oxooxetan Lipase inhibitor
Palmostatin-M	LYsophospholipase_carboxylesterase ABHD17-depalmitoylase ABHD6-Lip S9N_PREPL_Peptidase_S9	Oxooxetan Sulfur Compound
Palmostatin-B	ABHD16 Thioesterase Plant_Biomass_Hydrol_Est ABHD17-depalmitoylase ABHD6-Lip LYsophospholipase_carboxylesterase S9N_PREPL_Peptidase_S9	Oxooxetan Dimethoxyphenyl
Ebelactone-A	Homoserine_transacetylase Pancreatic_lipase ACPH_Peptidase_S9	Oxooxetan Natural
Ebelactone-B	Cutinase Carboxypeptidase_S10 Hepatic_Lipase Lipoprotein_Lipase Pancreatic_lipase	Oxooxetan Natural
Esterastin	Acidic_Lipase Pancreatic_lipase	Oxooxetan Natural Lipase inhibitor
Panclicin-D	Pancreatic_lipase	Oxooxetan Natural
Valilactone	Pancreatic_lipase	Oxooxetan Natural
Lipstatin	Pancreatic_lipase	Oxooxetan Natural Lipase inhibitor
MB064	Lipase_3	ABPP-Probe Boron compound Boranuidatricyclo BODIPY-derivative Triazol Oxooxetan Tridecyl Fluorescent Probe
THL-10d	A85-Mycolyl-transferase	Oxooxetan Lipase inhibitor Benzyloxycarbonyl
Orlistat	AlphaBeta_hydrolase Acidic_Lipase Pancreatic_lipase Thioesterase Carb_B_Chordata ABHD6-Lip Lipase_3 Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip Cutinase ABHD16 A85-Mycolyl-transferase PE-PPE Plasmodium_subtelomeric_PST-A Bacterial_lip_FamI.6	Oxooxetan Lipase inhibitor