L-benzylsuccinate
L-benzylsuccinate was developed as a potent competitive inhibitor of metalloproteinase carboxypeptidase A (CPA)
General
Type : Not A\/B H target
Chemical_Nomenclature : (2R)-2-benzylbutanedioic acid
Canonical SMILES : C1=CC=C(C=C1)CC(CC(=O)O)C(=O)O
InChI : InChI=1S\/C11H12O4\/c12-10(13)7-9(11(14)15)6-8-4-2-1-3-5-8\/h1-5,9H,6-7H2,(H,12,13)(H,14,15)\/t9-\/m1\/s1
InChIKey : GTOFKXZQQDSVFH-SECBINFHSA-N
Other name(s) : (R)-2-benzylsuccinic acid || (R)-2-benzylsuccinate || CHEMBL259621 || CHEBI:41241
MW : 208.21
Formula : C11H12O4
CAS_number : 21307-97-1
PubChem : 444797
UniChem : GTOFKXZQQDSVFH-SECBINFHSA-N
Target
Families : L-benzylsuccinate ligand of proteins in family
Carboxypeptidase_S10
Structure :
1WHT
Protein :
wheat-cbp02
References (1)
| Title : Structure of the complex of L-benzylsuccinate with wheat serine carboxypeptidase II at 2.0-A resolution - Bullock_1994_Biochemistry_33_11127 |
| Author(s) : Bullock TL , Branchaud B , Remington SJ |
| Ref : Biochemistry , 33 :11127 , 1994 |
| Abstract : |
| PubMedSearch : Bullock_1994_Biochemistry_33_11127 |
| PubMedID: 7727364 |
| Gene_locus related to this paper: wheat-cbp02 |