Type : Urea derivative, Azetidin
Chemical_Nomenclature : (4aR,8aS)-6-[3-[(4-chloro-2-phenoxyphenyl)methoxy]azetidine-1-carbonyl]-4,4a,5,7,8,8a-hexahydropyrido[4,3-b][1,4]oxazin-3-one
Canonical SMILES : C1CN(CC2C1OCC(=O)N2)C(=O)N3CC(C3)OCC4=C(C=C(C=C4)Cl)OC5=CC=CC=C5
InChI : InChI=1S\/C24H26ClN3O5\/c25-17-7-6-16(22(10-17)33-18-4-2-1-3-5-18)14-31-19-11-28(12-19)24(30)27-9-8-21-20(13-27)26-23(29)15-32-21\/h1-7,10,19-21H,8-9,11-15H2,(H,26,29)\/t20-,21+\/m1\/s1
InChIKey : LDQPCFUWDSJVGK-RTWAWAEBSA-N
Other name(s) : Compound 239 || Cpd239 || CHEMBL4875383 || SCHEMBL21730690 || BDBM50569654
MW : 471.9
Formula : C24H26ClN3O5
CAS_number :
PubChem : 146386830
UniChem : LDQPCFUWDSJVGK-RTWAWAEBSA-N
Families : MGLL-IN-Cpd239 ligand of proteins in family
Monoglyceridelipase_lysophospholip
Protein :
human-MGLL
Title : Heterocyclic Compounds as Monoacylglycerol Lipase (MAGL) Inhibitors - |
Author(s) : Sabnis RW |
Ref : ACS Med Chem Lett , 12 :536 , 2021 |
PubMedID: 33859792 |
Gene_locus related to this paper: human-MGLL |