NBD-5-acylcholine
fluorescent analog of acetylcholine used both as ACHE and ACh receptor ligand
General
Type : Trimethylammonium, Analogue of substrate, NBD-nitro-benzoxadiazol-fluorescent, Benzoxadiazole
Chemical_Nomenclature : trimethyl-[2-[6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanoyloxy]ethyl]azanium
Canonical SMILES : C[N+](C)(C)CCOC(=O)CCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-]
InChI : InChI=1S\/C17H26N5O5\/c1-22(2,3)11-12-26-15(23)7-5-4-6-10-18-13-8-9-14(21(24)25)17-16(13)19-27-20-17\/h8-9,18H,4-7,10-12H2,1-3H3\/q+1
InChIKey : BLWHUXXKWKVPAY-UHFFFAOYSA-N
Other name(s) : AC1Q1Z0M || AC1L4Y24
MW : 380.4
Formula : C17H26N5O5+
CAS_number : 70214-86-7
PubChem : 194337
UniChem : BLWHUXXKWKVPAY-UHFFFAOYSA-N
Target
Families : NBD-5-acylcholine ligand of proteins in family
ACHE
References (9)
| Title : Equilibrium binding of cholinergic ligands to the membrane-bound acetylcholine receptor - Covarrubias_1986_J.Biol.Chem_261_14955 |
| Author(s) : Covarrubias M , Prinz H , Meyers HW , Maelicke A |
| Ref : Journal of Biological Chemistry , 261 :14955 , 1986 |
| Abstract : |
| PubMedSearch : Covarrubias_1986_J.Biol.Chem_261_14955 |
| PubMedID: 3771559 |
| Title : Ligand-specific state transitions of the membrane-bound acetylcholine receptor - Covarrubias_1984_FEBS.Lett_169_229 |
| Author(s) : Covarrubias M , Prinz H , Maelicke A |
| Ref : FEBS Letters , 169 :229 , 1984 |
| Abstract : |
| PubMedSearch : Covarrubias_1984_FEBS.Lett_169_229 |
| PubMedID: 6714426 |
| Title : Appendix. Synthesis of NBD-5-acylcholine - |
| Author(s) : Jurss R , Maelicke A |
| Ref : Journal of Biological Chemistry , 258 :10272 , 1983 |
| PubMedID: 6885780 |
| Title : Synthesis and properties of NBD-n-acylcholines, fluorescent analogs of acetylcholine - Meyers_1983_Eur.J.Biochem_137_399 |
| Author(s) : Meyers HW , Jurss R , Brenner HR , Fels G , Prinz H , Watzke H , Maelicke A |
| Ref : European Journal of Biochemistry , 137 :399 , 1983 |
| Abstract : |
| PubMedSearch : Meyers_1983_Eur.J.Biochem_137_399 |
| PubMedID: 6607162 |
| Title : Interaction of cholinergic ligands with the purified acetylcholine receptor protein. I. Equilibrium binding studies - Prinz_1983_J.Biol.Chem_258_10263 |
| Author(s) : Prinz H , Maelicke A |
| Ref : Journal of Biological Chemistry , 258 :10263 , 1983 |
| Abstract : |
| PubMedSearch : Prinz_1983_J.Biol.Chem_258_10263 |
| PubMedID: 6885779 |
| Title : Interaction of cholinergic ligands with the purified acetylcholine receptor protein. II. Kinetic studies - Prinz_1983_J.Biol.Chem_258_10273 |
| Author(s) : Prinz H , Maelicke A |
| Ref : Journal of Biological Chemistry , 258 :10273 , 1983 |
| Abstract : |
| PubMedSearch : Prinz_1983_J.Biol.Chem_258_10273 |
| PubMedID: 6885781 |
| Title : Investigation of reduced nicotinamide adenine dinucleotide phosphate and acyl-binding sites on avian fatty acid synthase - Cardon_1982_Biochemistry_21_2863 |
| Author(s) : Cardon JW , Hammes GG |
| Ref : Biochemistry , 21 :2863 , 1982 |
| Abstract : |
| PubMedSearch : Cardon_1982_Biochemistry_21_2863 |
| PubMedID: 7104298 |
| Title : Interaction of acetylcholine esterase with fluorescent analogs of acetylcholine - |
| Author(s) : Jurss R , Maelicke A |
| Ref : Journal of Biological Chemistry , 256 :2887 , 1981 |
| PubMedID: 7204380 |
| Title : NBD-5-acylcholine: fluorescent analog of acetylcholine and agonist at the neuromuscular junction - Jurss_1979_Proc.Natl.Acad.Sci.U.S.A_76_1064 |
| Author(s) : Jurss R , Prinz H , Maelicke A |
| Ref : Proc Natl Acad Sci U S A , 76 :1064 , 1979 |
| Abstract : |
| PubMedSearch : Jurss_1979_Proc.Natl.Acad.Sci.U.S.A_76_1064 |
| PubMedID: 312497 |