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Trimethylammonium

General

Charged part of the choline product of hydrolysis of Acetylcholine. Binds the anionic sites (CAS and PAS) of acetylcholinesterase. Building block for many inhibitors of cholinesterase (analogy with substrate gives the high afinity)
Inhibitor Main targeted enzyme families Type Structure
Dimethylpipyrazinoammonium-benzylidine-dimethoxy-inden-one-cpd5g ACHE Trimethylammonium Ammonium Inden
8AM2-N0C BCHE Trimethylammonium Ammonium Pyridine Hydrazinylidene
Thiocholine-thionitrobenzoic-acid BCHE Trimethylammonium Ammonium Sulfur Compound Benzoate
8AM1-5a BCHE Trimethylammonium Ammonium Pyridine
Cetrimonium Trimethylammonium Ammonium
MFPhCh ACHE Tammelin ester Organophosphate Choline ester Trimethylammonium Ammonium
MFPCh ACHE Tammelin ester Organophosphate Choline ester Trimethylammonium Ammonium
MFPbetaCh ACHE Tammelin ester Organophosphate Choline ester Trimethylammonium Ammonium
3152-CT Carbamate Chemical Warfare Agent Trimethylammonium Ammonium Nerve Agent Carbamate
EA-3966 ACHE Carbamate Chemical Warfare Agent Trimethylammonium Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
BisQ ACHE Analogue of substrate Trimethylammonium Ammonium Bisquaternary Not AlphaBeta Hydrolase target Nicotinic agonist Photoswitch
p-phenylazophenyltrimethylammonium ACHE Photoswitch Trimethylammonium Ammonium Not AlphaBeta Hydrolase target Nicotinic agonist
N-p-phenylazophenylcarbamylcholine ACHE Photoswitch Trimethylammonium Ammonium Not AlphaBeta Hydrolase target Nicotinic agonist
Hypaphorine ACHE Not AlphaBeta Hydrolase target Natural Derivative of Tryptophan Indole Propionate Trimethylammonium Ammonium
Carpronium ACHE Analogue of substrate Trimethylammonium Ammonium
NBD-5-acylcholine ACHE Trimethylammonium Ammonium Analogue of substrate NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
AMTS13 ACHE Trimethylammonium Ammonium Sulfur Compound
Demecarium ACHE BCHE Trimethylammonium Ammonium Bisquaternary Drug
3-Hydroxy-Phenyl-Trimethyl-Ammonium ACHE Trimethylammonium Ammonium
3-Trimethylammonium-aniline ACHE Trimethylammonium Ammonium
4-Trimethylammonium-aniline ACHE Trimethylammonium
BW62C47 ACHE Bisquaternary Trimethylammonium Ammonium
4-hydroxy-N,N,N-trimethylpentanaminium ACHE Trimethylammonium Ammonium Analogue of substrate
4-oxo-N,N,N-trimethylpentanaminium ACHE Trimethylammonium Ammonium Analogue of substrate
Carbachol ACHE BCHE Not AlphaBeta Hydrolase target Carbamate Trimethylammonium Ammonium Analogue of substrate Drug Muscarinic agonist Nicotinic agonist
CHMP-thiocholine ACHE Organophosphate Trimethylammonium Ammonium Sulfur Compound
Choline ACHE BCHE Natural Trimethylammonium Ammonium
Decamethonium BCHE Bisquaternary Trimethylammonium Ammonium Neuromuscular Nondepolarizing Agents Nicotinic antagonist Drug Not AlphaBeta Hydrolase target
Decidium ACHE Bisquaternary Trimethylammonium Ammonium Phenanthridinium Derivative of Propidium
Nu-1250 ACHE Carbamate Trimethylammonium Ammonium Organochlorine
Nu-1197 ACHE Carbamate Trimethylammonium Ammonium
DMBMP-thiocholine ACHE Organophosphate Trimethylammonium Ammonium Sulfur Compound
Echothiophate BCHE Drug Organophosphate Sulfur Compound Organothiophosphate Trimethylammonium Ammonium
Edrophonium ACHE BCHE Drug Quaternary compound Trimethylammonium Ammonium Organochlorine
Hexamethonium ACHE Bisquaternary Nicotinic antagonist Trimethylammonium Ammonium
Neostigmine~Prostigmine ACHE BCHE Stigmine Derivative of Neostigmine~Prostigmine Carbamate Trimethylammonium Ammonium
Fmoc-Lys(Boc)-trimethylammonium-5e BCHE Fluoren Carbamate Trimethylammonium Ammonium
Ro-2-0683 BCHE Trimethylammonium Ammonium Carbamate
Succinylcholine~Suxamethonium BCHE Neuromuscular Nondepolarizing Agents Bisquaternary Trimethylammonium Ammonium Not AlphaBeta Hydrolase target
Tetramethylammonium ACHE Quaternary compound Trimethylammonium Ammonium
TMAmethylborinicacid ACHE Quaternary compound Trimethylammonium Ammonium Boron compound
NAF ACHE Trifluoro Quaternary compound Trimethylammonium Ammonium Transition state analogue
TMTFA ACHE Trifluoro Trimethylammonium Ammonium Quaternary compound Transition state analogue Halo ketone
8AM2-N0C BCHE Trimethylammonium Ammonium Pyridine Hydrazinylidene
Thiocholine-thionitrobenzoic-acid BCHE Trimethylammonium Ammonium Sulfur compound Benzoate
8AM1-5a BCHE Trimethylammonium Ammonium Pyridine
Cetrimonium Trimethylammonium Ammonium
MFPhCh ACHE Tammelin ester Organophosphate Choline ester Trimethylammonium Ammonium
MFPCh ACHE Tammelin ester Organophosphate Choline ester Trimethylammonium Ammonium
MFPbetaCh ACHE Tammelin ester Organophosphate Choline ester Trimethylammonium Ammonium
3152-CT Carbamate Chemical Warfare Agent Trimethylammonium Ammonium Nerve Agent Carbamate
EA-3966 ACHE Carbamate Chemical Warfare Agent Trimethylammonium Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
BisQ ACHE Analogue of substrate Trimethylammonium Ammonium Bisquaternary Not AlphaBeta Hydrolase target Nicotinic agonist Photoswitch
p-phenylazophenyltrimethylammonium ACHE Photoswitch Trimethylammonium Ammonium Not AlphaBeta Hydrolase target Nicotinic agonist
N-p-phenylazophenylcarbamylcholine ACHE Photoswitch Trimethylammonium Ammonium Not AlphaBeta Hydrolase target Nicotinic agonist
Hypaphorine ACHE Not AlphaBeta Hydrolase target Natural Derivative of Tryptophan Indole Propionate Trimethylammonium Ammonium
Carpronium ACHE Analogue of substrate Trimethylammonium Ammonium
NBD-5-acylcholine ACHE Trimethylammonium Ammonium Analogue of substrate NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
AMTS13 ACHE Trimethylammonium Ammonium Sulfur compound
Demecarium ACHE BCHE Trimethylammonium Ammonium Bisquaternary Drug
3-Hydroxy-Phenyl-Trimethyl-Ammonium ACHE Trimethylammonium Ammonium
3-Trimethylammonium-aniline ACHE Trimethylammonium Ammonium
4-Trimethylammonium-aniline ACHE Trimethylammonium
BW62C47 ACHE Bisquaternary Trimethylammonium Ammonium
4-hydroxy-N,N,N-trimethylpentanaminium ACHE Trimethylammonium Ammonium Analogue of substrate
4-oxo-N,N,N-trimethylpentanaminium ACHE Trimethylammonium Ammonium Analogue of substrate
Carbachol ACHE BCHE Not AlphaBeta Hydrolase target Carbamate Trimethylammonium Ammonium Analogue of substrate Drug Muscarinic agonist Nicotinic agonist
CHMP-thiocholine ACHE Organophosphate Trimethylammonium Ammonium Sulfur compound
Choline ACHE BCHE Natural Trimethylammonium Ammonium
Decamethonium BCHE Bisquaternary Trimethylammonium Ammonium Neuromuscular Nondepolarizing Agents Nicotinic antagonist Drug Not AlphaBeta Hydrolase target
Decidium ACHE Bisquaternary Trimethylammonium Ammonium Phenanthridinium Derivative of Propidium
Nu-1250 ACHE Carbamate Trimethylammonium Ammonium Organochlorine
Nu-1197 ACHE Carbamate Trimethylammonium Ammonium
DMBMP-thiocholine ACHE Organophosphate Trimethylammonium Ammonium Sulfur compound
Echothiophate BCHE Drug Organophosphate Sulfur compound Organothiophosphate Trimethylammonium Ammonium
Edrophonium ACHE BCHE Drug Quaternary compound Trimethylammonium Ammonium Organochlorine
Hexamethonium ACHE Bisquaternary Nicotinic antagonist Trimethylammonium Ammonium
Neostigmine~Prostigmine ACHE BCHE Stigmine Derivative of Neostigmine~Prostigmine Carbamate Trimethylammonium Ammonium
Fmoc-Lys(Boc)-trimethylammonium-5e BCHE Fluoren Carbamate Trimethylammonium Ammonium
Ro-2-0683 BCHE Trimethylammonium Ammonium Carbamate
Succinylcholine~Suxamethonium BCHE Neuromuscular Nondepolarizing Agents Bisquaternary Trimethylammonium Ammonium Not AlphaBeta Hydrolase target
Tetramethylammonium ACHE Quaternary compound Trimethylammonium Ammonium
TMAmethylborinicacid ACHE Quaternary compound Trimethylammonium Ammonium Boron compound
NAF ACHE Trifluoro Quaternary compound Trimethylammonium Ammonium Transition state analogue
TMTFA ACHE Trifluoro Trimethylammonium Ammonium Quaternary compound Transition state analogue Halo ketone
8AM2-N0C BCHE Trimethylammonium Ammonium Pyridine Hydrazinylidene
Thiocholine-thionitrobenzoic-acid BCHE Trimethylammonium Ammonium Sulfur compound Benzoate
8AM1-5a BCHE Trimethylammonium Ammonium Pyridine
Cetrimonium Trimethylammonium Ammonium
MFPhCh ACHE Tammelin ester Organophosphate Choline ester Trimethylammonium Ammonium
MFPCh ACHE Tammelin ester Organophosphate Choline ester Trimethylammonium Ammonium
MFPbetaCh ACHE Tammelin ester Organophosphate Choline ester Trimethylammonium Ammonium
3152-CT Carbamate Chemical Warfare Agent Trimethylammonium Ammonium Nerve Agent Carbamate
EA-3966 ACHE Carbamate Chemical Warfare Agent Trimethylammonium Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
BisQ ACHE Analogue of substrate Trimethylammonium Ammonium Bisquaternary Not AlphaBeta Hydrolase target Nicotinic agonist Photoswitch
p-phenylazophenyltrimethylammonium ACHE Photoswitch Trimethylammonium Ammonium Not AlphaBeta Hydrolase target Nicotinic agonist
N-p-phenylazophenylcarbamylcholine ACHE Photoswitch Trimethylammonium Ammonium Not AlphaBeta Hydrolase target Nicotinic agonist
Hypaphorine ACHE Not AlphaBeta Hydrolase target Natural Derivative of Tryptophan Indole Propionate Trimethylammonium Ammonium
Carpronium ACHE Analogue of substrate Trimethylammonium Ammonium
NBD-5-acylcholine ACHE Trimethylammonium Ammonium Analogue of substrate NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
AMTS13 ACHE Trimethylammonium Ammonium Sulfur compound
Demecarium ACHE BCHE Trimethylammonium Ammonium Bisquaternary Drug
3-Hydroxy-Phenyl-Trimethyl-Ammonium ACHE Trimethylammonium Ammonium
3-Trimethylammonium-aniline ACHE Trimethylammonium Ammonium
4-Trimethylammonium-aniline ACHE Trimethylammonium
BW62C47 ACHE Bisquaternary Trimethylammonium Ammonium
4-hydroxy-N,N,N-trimethylpentanaminium ACHE Trimethylammonium Ammonium Analogue of substrate
4-oxo-N,N,N-trimethylpentanaminium ACHE Trimethylammonium Ammonium Analogue of substrate
Carbachol ACHE BCHE Not AlphaBeta Hydrolase target Carbamate Trimethylammonium Ammonium Analogue of substrate Drug Muscarinic agonist Nicotinic agonist
CHMP-thiocholine ACHE Organophosphate Trimethylammonium Ammonium Sulfur compound
Choline ACHE BCHE Natural Trimethylammonium Ammonium
Decamethonium BCHE Bisquaternary Trimethylammonium Ammonium Neuromuscular Nondepolarizing Agents Nicotinic antagonist Drug Not AlphaBeta Hydrolase target
Decidium ACHE Bisquaternary Trimethylammonium Ammonium Phenanthridinium Derivative of Propidium
Nu-1250 ACHE Carbamate Trimethylammonium Ammonium Organochlorine
Nu-1197 ACHE Carbamate Trimethylammonium Ammonium
DMBMP-thiocholine ACHE Organophosphate Trimethylammonium Ammonium Sulfur compound
Echothiophate BCHE Drug Organophosphate Sulfur compound Organothiophosphate Trimethylammonium Ammonium
Edrophonium ACHE BCHE Drug Quaternary compound Trimethylammonium Ammonium Organochlorine
Hexamethonium ACHE Bisquaternary Nicotinic antagonist Trimethylammonium Ammonium
Neostigmine~Prostigmine ACHE BCHE Stigmine Derivative of Neostigmine~Prostigmine Carbamate Trimethylammonium Ammonium
Fmoc-Lys(Boc)-trimethylammonium-5e BCHE Fluoren Carbamate Trimethylammonium Ammonium
Ro-2-0683 BCHE Trimethylammonium Ammonium Carbamate
Succinylcholine~Suxamethonium BCHE Neuromuscular Nondepolarizing Agents Bisquaternary Trimethylammonium Ammonium Not AlphaBeta Hydrolase target
Tetramethylammonium ACHE Quaternary compound Trimethylammonium Ammonium
TMAmethylborinicacid ACHE Quaternary compound Trimethylammonium Ammonium Boron compound
NAF ACHE Trifluoro Quaternary compound Trimethylammonium Ammonium Transition state analogue
TMTFA ACHE Trifluoro Trimethylammonium Ammonium Quaternary compound Transition state analogue Halo ketone