Phenyl-di-n-pentylphosphinate
Phenyl di-n-pentylphosphinate PPP is a potent inhibitor of neuropathy target esterase NTE with negligible effect on acetylcholinesterase
General
Type : Organophosphate, NTE inhibitor, Not A\/B H target
Chemical_Nomenclature : dipentylphosphoryloxybenzene
Canonical SMILES : CCCCCP(=O)(CCCCC)OC1=CC=CC=C1
InChI : InChI=1S\/C16H27O2P\/c1-3-5-10-14-19(17,15-11-6-4-2)18-16-12-8-7-9-13-16\/h7-9,12-13H,3-6,10-11,14-15H2,1-2H3
InChIKey : TUJWIYZCAPMHSA-UHFFFAOYSA-N
Other name(s) : Phenyl di-n-pentylphosphinate || PDNP || PDPP || Phenyl dipentylphosphinate || Dipentylphosphoryloxybenzene
Target
References (2)
| Title : Phospholipase B activity and organophosphorus compound toxicity in cultured neural cells - Read_2007_Toxicol.Appl.Pharmacol_219_190 |
| Author(s) : Read DJ , Langford L , Barbour HR , Forshaw PJ , Glynn P |
| Ref : Toxicol Appl Pharmacol , 219 :190 , 2007 |
| Abstract : |
| PubMedSearch : Read_2007_Toxicol.Appl.Pharmacol_219_190 |
| PubMedID: 16963094 |
| Title : Prophylaxis against and promotion of organophosphate-induced delayed neuropathy by phenyl di-n-pentylphosphinate - Johnson_1993_Chem.Biol.Interact_87_449 |
| Author(s) : Johnson MK , Read DJ |
| Ref : Chemico-Biological Interactions , 87 :449 , 1993 |
| Abstract : |
| PubMedSearch : Johnson_1993_Chem.Biol.Interact_87_449 |
| PubMedID: 8344002 |