Phenyl-di-n-pentylphosphinate

Phenyl di-n-pentylphosphinate PPP is a potent inhibitor of neuropathy target esterase NTE with negligible effect on acetylcholinesterase

General

Type : Organophosphate, NTE inhibitor, Not A\/B H target

Chemical_Nomenclature : dipentylphosphoryloxybenzene

Canonical SMILES : CCCCCP(=O)(CCCCC)OC1=CC=CC=C1

InChI : InChI=1S\/C16H27O2P\/c1-3-5-10-14-19(17,15-11-6-4-2)18-16-12-8-7-9-13-16\/h7-9,12-13H,3-6,10-11,14-15H2,1-2H3

InChIKey : TUJWIYZCAPMHSA-UHFFFAOYSA-N

Other name(s) : Phenyl di-n-pentylphosphinate  ||  PDNP  ||  PDPP  ||  Phenyl dipentylphosphinate  ||  Dipentylphosphoryloxybenzene


MW : 282.35

Formula : C16H27O2P

CAS_number :

PubChem : 151930

UniChem : TUJWIYZCAPMHSA-UHFFFAOYSA-N

Target

References (2)

Title : Phospholipase B activity and organophosphorus compound toxicity in cultured neural cells - Read_2007_Toxicol.Appl.Pharmacol_219_190
Author(s) : Read DJ , Langford L , Barbour HR , Forshaw PJ , Glynn P
Ref : Toxicol Appl Pharmacol , 219 :190 , 2007
Abstract :
PubMedSearch : Read_2007_Toxicol.Appl.Pharmacol_219_190
PubMedID: 16963094

Title : Prophylaxis against and promotion of organophosphate-induced delayed neuropathy by phenyl di-n-pentylphosphinate - Johnson_1993_Chem.Biol.Interact_87_449
Author(s) : Johnson MK , Read DJ
Ref : Chemico-Biological Interactions , 87 :449 , 1993
Abstract :
PubMedSearch : Johnson_1993_Chem.Biol.Interact_87_449
PubMedID: 8344002