Phenyl-phenylpyridin-oxadiazol-cpd5a
IC50 46.9 and 3.5 nM against AChE and BuChE
General
Type : Oxadiazol, Multitarget, Pyridine
Chemical_Nomenclature : N-Phenyl-5-(5-phenylpyridin-3-yl)-1,3,4-oxadiazol-2-amine
Canonical SMILES : N1=C(OC(=N1)C2=CC(=CN=C2)C3=CC=CC=C3)NC4=CC=CC=C4
InChI : InChI=1S\/C19H14N4O\/c1-3-7-14(8-4-1)15-11-16(13-20-12-15)18-22-23-19(24-18)21-17-9-5-2-6-10-17\/h1-13H,(H,21,23)
InChIKey : RRHFUXXJRJCRBD-UHFFFAOYSA-N
Other name(s) : Compound 5a
Target
References (1)
| Title : Unleashing new MTDL AChE and BuChE inhibitors as potential anti-AD therapeutic agents: In vitro, in vivo and in silico studies - Zaafar_2024_Int.J.Biol.Macromol__131740 |
| Author(s) : Zaafar D , Elghazawy NH , Hassan A , Mahmoud MY , Bakr AF , Arafa RK |
| Ref : Int J Biol Macromol , :131740 , 2024 |
| Abstract : |
| PubMedSearch : Zaafar_2024_Int.J.Biol.Macromol__131740 |
| PubMedID: 38653428 |