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Pyridine

General

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH-) replaced by a nitrogen atom. Pyridine is not abundant in nature, except for the leaves and roots of belladonna (Atropa belladonna) and in marshmallow (Althaea officinalis, Guimauve officinale). Pyridine derivatives, however, are often part of biomolecules such as alkaloids. Building block for many inhibitors of enzymes
Inhibitor Main targeted enzyme families Type Structure
CHEMBL5854413 Monoglyceridelipase_lysophospholip Quinazoline Piperazine Benzoxazol Pyridine
Amiridine-pyridoximine-cpd3c ACHE BCHE Derivative of Amiridine Quinoline Pyridine Alkyl linked bis-ligand anti-Abeta-aggregation Multitarget
Amiridine-pyridoxamine-cpd4c ACHE BCHE Derivative of Amiridine Quinoline Pyridine Alkyl linked bis-ligand anti-Abeta-aggregation Multitarget
Cyclopentyl-pyridyl-benzoxazol-cyclopropyl-triazol-azaspiro-heptan-methanone-Cpd29 Monoglyceridelipase_lysophospholip Benzoxazol Pyridine Piperazine Triazol Azaspiro Cyclopropyl
Chlorooxazolo-pyridin-piperazin-cyclobutylcyclopropyl-pyridyl-benzoxazol-methanone-Cpd27 Monoglyceridelipase_lysophospholip Benzoxazol Pyridine Piperazine Cyclobutyl Cyclopropyl Organochlorine
Chlorooxazolo-pyridin-piperazin-cyclopentyl-pyridyl-benzoxazol-methanone-Cpd23 Monoglyceridelipase_lysophospholip Benzoxazol Pyridine Piperazine Organochlorine
FZQ-21 Epoxide_hydrolase Urea derivative Pyridine
Naphthalen-pyridin-quinuclidin-carbamate-Cpd6b BCHE Nicotinic agonist Multitarget Naphthalen Quinuclidine Azabicyclo Carbamate Pyridine
Pyridin-quinuclidin-phenylcarbamate-Cpd7a Nicotinic agonist Multitarget Quinuclidine Carbamate Pyridine Azabicyclo
A1IKD BCHE Naphthalen Pyridine Pyridazine
A1IKC BCHE Naphthalen Pyridine Pyridazine
Dimethyl-pyrazolopyridine-Ethyl-methyl-triazole-carboxylate-Cpd23 ACHE Pyridine Pyrazole Triazol GSK-3 kinase inhibitor Multitarget
AChE-Nrf2modulator-1 ACHE Pyridine Oxadiazol Nrf2 modulator Derivative of Donepezil Multitarget
HSL-IN-1 Hormone-sensitive_lipase_like Boron compound Pyridine Trifluoro
ZQ-19 Monoglyceridelipase_lysophospholip Cyanide Pyridine Sulfur Compound Organochlorine
ZQ-7 Monoglyceridelipase_lysophospholip Cyanide Pyridine Sulfur Compound
Benzothiazol-Phenyl-Piperazine-Pyridine-Cpd18 ACHE Benzothiazol Sulfur Compound Piperazine Pyridine Fluorescent Probe
CHEMBL1688431-Cpd4e7 DPP4N_Peptidase_S9 Pyridine Cyanide Organochlorine
2,6-bis(N-methylpyridinium-3-ylmethylene)cyclohexanone-Cpd2A ACHE Bisquaternary Pyridine
CHEMBL4595876 ACHE Multitarget Pyridine Sigma1R ligand Cyanide Alkyne Benzylpiperidine Derivative of Donepezil
CHEMBL3338952 BCHE Triazol Thiadiazol Pyridine Sulfur Compound
CHEMBL5176915 Monoglyceridelipase_lysophospholip Pyridine Piperidine Trifluoro
MAGL-IN-10-Cpd28 Monoglyceridelipase_lysophospholip Pyridine Piperidine Trifluoro Sulfur Compound
Galantamine-benzylpyridine-C2 ACHE BCHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Pyridine Benzazepin Azepane
Emodin Natural Pyridine Acridine Not AlphaBeta Hydrolase target
Aloe-emodin-C3 ACHE Pyridine Acridine Organochlorine
CHEMBL3313966 ACHE Bisquaternary Pyridine Hydrazinylidene Organochlorine
CHEMBL4278686 ACHE GSK-3 kinase inhibitor Derivative of Tacrine Acridine Multitarget Thiazole Carboxamide Pyridine Cyclopropyl Sulfur Compound
SCHEMBL5255404 Epoxide_hydrolase Pyridine
Phenyl-phenylpyridin-oxadiazol-cpd5a ACHE BCHE Oxadiazol Multitarget Pyridine
X20403 Thioesterase Pyridine Triazol Cyclopropyl Dimethoxyphenyl
X20404 Thioesterase Pyridine Triazol Dimethoxyphenyl
PyrTac-5f ACHE Derivative of Tacrine Acridine Multitarget Protein Phosphatase activator Pyridine
Tacrine-Sibiriline-Cpd7 BCHE ACHE Multitarget Acridine Derivative of Tacrine Alkyl linked bis-ligand Pyridine Carbamate Pyrrolidine Antioxidant
Pyrazolopyridine-Cpd37 Monoglyceridelipase_lysophospholip Pyridine Pyrazole
(S)Aporphine-N-benzylpyridinium ACHE Isoquinoline Pyridine Alkaloid Organochlorine
CHEMBL5206601 ACHE anti-Abeta-aggregation Multitarget Pyridine Dimethoxyphenyl
8AEV-LWU ACHE Pyridine Pyrimidine
8AM2-N0C BCHE Trimethylammonium Ammonium Pyridine Hydrazinylidene
6RKY-K7K-phosphodiester Hormone-sensitive_lipase_like Multitarget Organophosphate Pyridine Metal ion chelator
ZK8 Hormone-sensitive_lipase_like Organophosphate Pyridine Metal ion chelator
6RKY-K7K Hormone-sensitive_lipase_like Organophosphate Pyridine Metal ion chelator
CHEMBL4289712 ABHD6-Lip Triazol Pyridine
Compound-47 abh_upf0017 Pyridine Carboxamide
3-aminocoumarin-N-benzylpyridinium-9h ACHE Coumarin Pyridine Chromen
8AM1-5a BCHE Trimethylammonium Ammonium Pyridine
LF-14 ACHE Pyridine Urea derivative
Bivalent-4-Aminopyridine-12i ACHE Pyridine Alkyl linked bis-ligand
JM-20 ACHE Benzodiazepin Not AlphaBeta Hydrolase target Pyridine Multitarget 2-nitrophenyl Azepane
Coumarin-Pyridine-3f ACHE BCHE Coumarin Pyridine Chromen
Difluorophenyl-pyridin-piperazin-1,3,4-oxadiazole-49 ACHE BCHE Oxadiazol Pyridine Piperazine BACE1-inhibitor
4-aminopyridine-1,3,4-oxadiazole-9 ACHE Oxadiazol Pyridine
N-dodecyl-pyridinyl-1,3,4-thiadiazol-amine-3t ACHE Sulfur Compound Pyridine Thiadiazol
5-pyrid-3-yl-1,3,4-oxadiazole-5e ACHE BCHE Oxadiazol Pyridine Organochlorine
Fragment-810 Pectinacetylesterase-Notum Pyridine Carboxamide
Fragment-872 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine
Fragment-110 Pectinacetylesterase-Notum Fragment inhibitor of Notum Urea derivative Pyridine
Sulfapyridine Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfonamide Sulfur Compound Antibiotic Pyridine Not AlphaBeta Hydrolase target Benzenesulfonamide
Fragment-147 Pectinacetylesterase-Notum Fragment inhibitor of Notum Carboxamide Pyridine Not AlphaBeta Hydrolase target
Fragment-297 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzodioxo Pyridine
Fragment-197 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine Benzoate
2-N-pyridin-2-ylbenzene-1,2-diamine Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine
Maybridge_18 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine Sulfur Compound
T-401 Monoglyceridelipase_lysophospholip Pyrrolidine Piperazine PET probe Pyridine Thiazole Sulfur Compound
EA-4056 ACHE Carbamate Chemical Warfare Agent Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
EA-3990 ACHE Carbamate Chemical Warfare Agent Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
EA-3966 ACHE Carbamate Chemical Warfare Agent Trimethylammonium Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
CHEMBL45663-49N-4Y2Q Epoxide_hydrolase Piperazine Pyridine Trifluoro
CHEMBL48137-49O-4Y2R Epoxide_hydrolase Piperazine Pyridine Cyanide Not AlphaBeta Hydrolase target Adrenergic-Receptor-ligand
VF2-Styrylpyridine-Dye Haloalkane_dehalogenase-HLD2 Pyridine Dye Fluorescent Probe Polymethine Organochlorine
thio-NAD PlaB Sulfur Compound Nicotinamide Organophosphate Pyridine Purine Aminopurin
LIPG-inhib-Compound32 Lipoprotein_Lipase Pyridine Benzothiazol Sulfur Compound Sulfonyl Cyclopropyl
XEN445 Lipoprotein_Lipase Pyridine Trifluoro
JVB Pectinacetylesterase-Notum Pyridine
FG1912 ACHE GSK-3 kinase inhibitor Multitarget Pyridine Piperidine Cyclopropyl Carboxamide Derivative of Donepezil
GD29 ACHE GSK-3 kinase inhibitor Multitarget Thiazole Pyridine Piperidine Cyclopropyl Carboxamide Sulfur Compound Derivative of Donepezil
GT15 ACHE Derivative of Tacrine Acridine GSK-3 kinase inhibitor Sulfur Compound Multitarget Carboxamide Pyridine Thiazole Cyclopropyl
BIA-10-2474 Carb_B_Chordata ABHD6-Lip Pyridine Imidazole FAAH inhibitor Multitarget Carboxamide
CHEMBL3402235 Epoxide_hydrolase Pyridine
BMS-744891 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL3112960-Cpd20d DPP4N_Peptidase_S9 Pyridine Organochlorine
CHEMBL2441952 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL1910114 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL1909991 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL1910111 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine Pyrimidine
CHEMBL1234565 Epoxide_hydrolase Pyridine Nicotinamide Carboxamide Pyrazole
TAK-100 DPP4N_Peptidase_S9 Pyridine
TAK-986 DPP4N_Peptidase_S9 Pyridine
33N Epoxide_hydrolase Pyridine Nicotinamide Carboxamide
SCHEMBL7329991 Epoxide_hydrolase Pyridine
CHEMBL4451596 Epoxide_hydrolase Sulfonamide Pyridine Trifluoro Sulfur Compound
3-amino-4-phenyl-pyrrolidine-15B DPP4N_Peptidase_S9 Trifluoro Pyrrolidine Pyridine Pyrimidine
MK0626 DPP4N_Peptidase_S9 Pyridine Pyrrolidine Triazol
ABC99 Pectinacetylesterase-Notum Pyridine Carbamate Organochlorine
SMR000042088 S9N_PREPL_Peptidase_S9 Pyridine Cyanide
ARI-3531 S9N_PPCE_Peptidase_S9 Pyridine Pyrrolidine Boron compound
CHEMBL1684295 Prolylcarboxypeptidase Pyrrolidine Imidazole Pyridine Oxadiazol Piperidine Benzimidazole Organochlorine
CHEMBL3086040 Prolylcarboxypeptidase Pyridine Carboxamide Morpholine
NVP-DPP728 DPP4N_Peptidase_S9 Cyanide Pyrrolidine Pyridine
ARI-3099 DPP4N_Peptidase_S9 ACPH_Peptidase_S9 Pyridine Pyrrolidine Boron compound
LEI105 Lipase_3 Pyridine Oxazole
P-10358 ACHE BCHE Carbamate Indole Pyridine
4,4-Bipyridine ACHE BCHE Pyridine
7-MEOTA-4-pyridinealdoxime ACHE Derivative of Tacrine Acridine Pyridine Pyridine-aldoxime
Dehydroevodiamine ACHE Natural Pyridine Indole beta-carboline Natural_modified Derivative of Evodiamine
Diethylparaquat ACHE Pyridinium Pyridine Herbicide
BChE-IN-21 BCHE Pyridine Quinoline Carboxamide
SB-1436 BCHE ACHE Pyridine Naphthalen Pyridinium anti-Abeta-aggregation Multitarget Organochlorine
hAChE-IN-6 BCHE ACHE Pyridine Pyrazole GSK-3 kinase inhibitor anti-tau-aggregation Multitarget Dimethoxyphenyl
Monoquat ACHE Pyridine
Morfamquat ACHE Pyridine Herbicide Morpholine
Distigmine BCHE Carbamate Stigmine Drug Pyridine
Pyridostigmine BCHE ACHE Carbamate Stigmine Drug Pyridine
RU-47213 ACHE Pyridine Organochlorine
N-Benzylpyridinium ACHE Pyridine Organochlorine
LEI104 Lipase_3 Pyridine Oxazole
Amiloride ACHE BCHE Carboxamide Drug Pyridine Not AlphaBeta Hydrolase target Organochlorine
KT-2-74 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
KT-2-108 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
KT-2-59 S9N_PPCE_Peptidase_S9 Pyrazole Pyridine Carboxamide
KT-2-75 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
YX45 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine
KT-1-147 S9N_PPCE_Peptidase_S9 Pyrazole Pyridine Carboxamide
JP-4-1-7 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
KT-2-126 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
JP-2-1-7 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
KT-2-197 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
KT-2-186 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
JP-7-1-7 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
CHEMBL5854413 Monoglyceridelipase_lysophospholip Quinazoline Piperazine Benzoxazol Pyridine
Amiridine-pyridoximine-cpd3c ACHE BCHE Derivative of Amiridine Quinoline Pyridine Alkyl linked bis-ligand anti-Abeta-aggregation Multitarget
Amiridine-pyridoxamine-cpd4c ACHE BCHE Derivative of Amiridine Quinoline Pyridine Alkyl linked bis-ligand anti-Abeta-aggregation Multitarget
Cyclopentyl-pyridyl-benzoxazol-cyclopropyl-triazol-azaspiro-heptan-methanone-Cpd29 Monoglyceridelipase_lysophospholip Benzoxazol Pyridine Piperazine Triazol Azaspiro Cyclopropyl
Chlorooxazolo-pyridin-piperazin-cyclobutylcyclopropyl-pyridyl-benzoxazol-methanone-Cpd27 Monoglyceridelipase_lysophospholip Benzoxazol Pyridine Piperazine Cyclobutyl Cyclopropyl Organochlorine
Chlorooxazolo-pyridin-piperazin-cyclopentyl-pyridyl-benzoxazol-methanone-Cpd23 Monoglyceridelipase_lysophospholip Benzoxazol Pyridine Piperazine Organochlorine
FZQ-21 Epoxide_hydrolase Urea derivative Pyridine
Naphthalen-pyridin-quinuclidin-carbamate-Cpd6b BCHE Nicotinic agonist Multitarget Naphthalen Quinuclidine Azabicyclo Carbamate Pyridine
Pyridin-quinuclidin-phenylcarbamate-Cpd7a Nicotinic agonist Multitarget Quinuclidine Carbamate Pyridine Azabicyclo
A1IKD BCHE Naphthalen Pyridine Pyridazine
A1IKC BCHE Naphthalen Pyridine Pyridazine
Dimethyl-pyrazolopyridine-Ethyl-methyl-triazole-carboxylate-Cpd23 ACHE Pyridine Pyrazole Triazol GSK-3 kinase inhibitor Multitarget
AChE-Nrf2modulator-1 ACHE Pyridine Oxadiazol Nrf2 modulator Derivative of Donepezil Multitarget
HSL-IN-1 Hormone-sensitive_lipase_like Boron compound Pyridine Trifluoro
ZQ-19 Monoglyceridelipase_lysophospholip Cyanide Pyridine Sulfur compound Organochlorine
ZQ-7 Monoglyceridelipase_lysophospholip Cyanide Pyridine Sulfur compound
Benzothiazol-Phenyl-Piperazine-Pyridine-Cpd18 ACHE Benzothiazol Sulfur compound Piperazine Pyridine Fluorescent Probe
CHEMBL1688431-Cpd4e7 DPP4N_Peptidase_S9 Pyridine Cyanide Organochlorine
2,6-bis(N-methylpyridinium-3-ylmethylene)cyclohexanone-Cpd2A ACHE Bisquaternary Pyridine
CHEMBL4595876 ACHE Multitarget Pyridine Sigma1R ligand Cyanide Alkyne Benzylpiperidine Derivative of Donepezil
CHEMBL3338952 BCHE Triazol Thiadiazol Pyridine Sulfur compound
CHEMBL5176915 Monoglyceridelipase_lysophospholip Pyridine Piperidine Trifluoro
MAGL-IN-10-Cpd28 Monoglyceridelipase_lysophospholip Pyridine Piperidine Trifluoro Sulfur compound
Galantamine-benzylpyridine-C2 ACHE BCHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Pyridine Benzazepin Azepane
Emodin Natural Pyridine Acridine Not AlphaBeta Hydrolase target
Aloe-emodin-C3 ACHE Pyridine Acridine Organochlorine
CHEMBL3313966 ACHE Bisquaternary Pyridine Hydrazinylidene Organochlorine
CHEMBL4278686 ACHE GSK-3 kinase inhibitor Derivative of Tacrine Acridine Multitarget Thiazole Carboxamide Pyridine Cyclopropyl Sulfur compound
SCHEMBL5255404 Epoxide_hydrolase Pyridine
Phenyl-phenylpyridin-oxadiazol-cpd5a ACHE BCHE Oxadiazol Multitarget Pyridine
X20403 Thioesterase Pyridine Triazol Cyclopropyl Dimethoxyphenyl
X20404 Thioesterase Pyridine Triazol Dimethoxyphenyl
PyrTac-5f ACHE Derivative of Tacrine Acridine Multitarget Protein Phosphatase activator Pyridine
Tacrine-Sibiriline-Cpd7 BCHE ACHE Multitarget Acridine Derivative of Tacrine Alkyl linked bis-ligand Pyridine Carbamate Pyrrolidine Antioxidant
Pyrazolopyridine-Cpd37 Monoglyceridelipase_lysophospholip Pyridine Pyrazole
(S)Aporphine-N-benzylpyridinium ACHE Isoquinoline Pyridine Alkaloid Organochlorine
CHEMBL5206601 ACHE anti-Abeta-aggregation Multitarget Pyridine Dimethoxyphenyl
8AEV-LWU ACHE Pyridine Pyrimidine
8AM2-N0C BCHE Trimethylammonium Ammonium Pyridine Hydrazinylidene
6RKY-K7K-phosphodiester Hormone-sensitive_lipase_like Multitarget Organophosphate Pyridine Metal ion chelator
ZK8 Hormone-sensitive_lipase_like Organophosphate Pyridine Metal ion chelator
6RKY-K7K Hormone-sensitive_lipase_like Organophosphate Pyridine Metal ion chelator
CHEMBL4289712 ABHD6-Lip Triazol Pyridine
Compound-47 abh_upf0017 Pyridine Carboxamide
3-aminocoumarin-N-benzylpyridinium-9h ACHE Coumarin Pyridine Chromen
8AM1-5a BCHE Trimethylammonium Ammonium Pyridine
LF-14 ACHE Pyridine Urea derivative
Bivalent-4-Aminopyridine-12i ACHE Pyridine Alkyl linked bis-ligand
JM-20 ACHE Benzodiazepin Not AlphaBeta Hydrolase target Pyridine Multitarget 2-nitrophenyl Azepane
Coumarin-Pyridine-3f ACHE BCHE Coumarin Pyridine Chromen
Difluorophenyl-pyridin-piperazin-1,3,4-oxadiazole-49 ACHE BCHE Oxadiazol Pyridine Piperazine BACE1-inhibitor
4-aminopyridine-1,3,4-oxadiazole-9 ACHE Oxadiazol Pyridine
N-dodecyl-pyridinyl-1,3,4-thiadiazol-amine-3t ACHE Sulfur compound Pyridine Thiadiazol
5-pyrid-3-yl-1,3,4-oxadiazole-5e ACHE BCHE Oxadiazol Pyridine Organochlorine
Fragment-810 Pectinacetylesterase-Notum Pyridine Carboxamide
Fragment-872 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine
Fragment-110 Pectinacetylesterase-Notum Fragment inhibitor of Notum Urea derivative Pyridine
Sulfapyridine Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfonamide Sulfur compound Antibiotic Pyridine Not AlphaBeta Hydrolase target Benzenesulfonamide
Fragment-147 Pectinacetylesterase-Notum Fragment inhibitor of Notum Carboxamide Pyridine Not AlphaBeta Hydrolase target
Fragment-297 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzodioxo Pyridine
Fragment-197 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine Benzoate
2-N-pyridin-2-ylbenzene-1,2-diamine Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine
Maybridge_18 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine Sulfur compound
T-401 Monoglyceridelipase_lysophospholip Pyrrolidine Piperazine PET probe Pyridine Thiazole Sulfur compound
EA-4056 ACHE Carbamate Chemical Warfare Agent Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
EA-3990 ACHE Carbamate Chemical Warfare Agent Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
EA-3966 ACHE Carbamate Chemical Warfare Agent Trimethylammonium Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
CHEMBL45663-49N-4Y2Q Epoxide_hydrolase Piperazine Pyridine Trifluoro
CHEMBL48137-49O-4Y2R Epoxide_hydrolase Piperazine Pyridine Cyanide Not AlphaBeta Hydrolase target Adrenergic-Receptor-ligand
VF2-Styrylpyridine-Dye Haloalkane_dehalogenase-HLD2 Pyridine Dye Fluorescent Probe Polymethine Organochlorine
thio-NAD PlaB Sulfur compound Nicotinamide Organophosphate Pyridine Purine Aminopurin
LIPG-inhib-Compound32 Lipoprotein_Lipase Pyridine Benzothiazol Sulfur compound Sulfonyl Cyclopropyl
XEN445 Lipoprotein_Lipase Pyridine Trifluoro
JVB Pectinacetylesterase-Notum Pyridine
FG1912 ACHE GSK-3 kinase inhibitor Multitarget Pyridine Piperidine Cyclopropyl Carboxamide Derivative of Donepezil
GD29 ACHE GSK-3 kinase inhibitor Multitarget Thiazole Pyridine Piperidine Cyclopropyl Carboxamide Sulfur compound Derivative of Donepezil
GT15 ACHE Derivative of Tacrine Acridine GSK-3 kinase inhibitor Sulfur compound Multitarget Carboxamide Pyridine Thiazole Cyclopropyl
BIA-10-2474 Carb_B_Chordata ABHD6-Lip Pyridine Imidazole FAAH inhibitor Multitarget Carboxamide
CHEMBL3402235 Epoxide_hydrolase Pyridine
BMS-744891 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL3112960-Cpd20d DPP4N_Peptidase_S9 Pyridine Organochlorine
CHEMBL2441952 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL1910114 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL1909991 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL1910111 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine Pyrimidine
CHEMBL1234565 Epoxide_hydrolase Pyridine Nicotinamide Carboxamide Pyrazole
TAK-100 DPP4N_Peptidase_S9 Pyridine
TAK-986 DPP4N_Peptidase_S9 Pyridine
33N Epoxide_hydrolase Pyridine Nicotinamide Carboxamide
SCHEMBL7329991 Epoxide_hydrolase Pyridine
CHEMBL4451596 Epoxide_hydrolase Sulfonamide Pyridine Trifluoro Sulfur compound
3-amino-4-phenyl-pyrrolidine-15B DPP4N_Peptidase_S9 Trifluoro Pyrrolidine Pyridine Pyrimidine
MK0626 DPP4N_Peptidase_S9 Pyridine Pyrrolidine Triazol
ABC99 Pectinacetylesterase-Notum Pyridine Carbamate Organochlorine
SMR000042088 S9N_PREPL_Peptidase_S9 Pyridine Cyanide
ARI-3531 S9N_PPCE_Peptidase_S9 Pyridine Pyrrolidine Boron compound
CHEMBL1684295 Prolylcarboxypeptidase Pyrrolidine Imidazole Pyridine Oxadiazol Piperidine Benzimidazole Organochlorine
CHEMBL3086040 Prolylcarboxypeptidase Pyridine Carboxamide Morpholine
NVP-DPP728 DPP4N_Peptidase_S9 Cyanide Pyrrolidine Pyridine
ARI-3099 DPP4N_Peptidase_S9 ACPH_Peptidase_S9 Pyridine Pyrrolidine Boron compound
LEI105 Lipase_3 Pyridine Oxazole
P-10358 ACHE BCHE Carbamate Indole Pyridine
4,4-Bipyridine ACHE BCHE Pyridine
7-MEOTA-4-pyridinealdoxime ACHE Derivative of Tacrine Acridine Pyridine Pyridine-aldoxime
Dehydroevodiamine ACHE Natural Pyridine Indole beta-carboline Natural_modified Derivative of Evodiamine
Diethylparaquat ACHE Pyridinium Pyridine Herbicide
BChE-IN-21 BCHE Pyridine Quinoline Carboxamide
SB-1436 BCHE ACHE Pyridine Naphthalen Pyridinium anti-Abeta-aggregation Multitarget Organochlorine
hAChE-IN-6 BCHE ACHE Pyridine Pyrazole GSK-3 kinase inhibitor anti-tau-aggregation Multitarget Dimethoxyphenyl
Monoquat ACHE Pyridine
Morfamquat ACHE Pyridine Herbicide Morpholine
Distigmine BCHE Carbamate Stigmine Drug Pyridine
Pyridostigmine BCHE ACHE Carbamate Stigmine Drug Pyridine
RU-47213 ACHE Pyridine Organochlorine
N-Benzylpyridinium ACHE Pyridine Organochlorine
LEI104 Lipase_3 Pyridine Oxazole
Amiloride ACHE BCHE Carboxamide Drug Pyridine Not AlphaBeta Hydrolase target Organochlorine
KT-2-74 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
KT-2-108 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
KT-2-59 S9N_PPCE_Peptidase_S9 Pyrazole Pyridine Carboxamide
KT-2-75 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
YX45 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine
KT-1-147 S9N_PPCE_Peptidase_S9 Pyrazole Pyridine Carboxamide
JP-4-1-7 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
KT-2-126 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
JP-2-1-7 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
KT-2-197 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
KT-2-186 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
JP-7-1-7 S9N_PPCE_Peptidase_S9 Pyrrolidine Pyrazole Pyridine Carboxamide
CHEMBL5854413 Monoglyceridelipase_lysophospholip Quinazoline Piperazine Benzoxazol Pyridine
Amiridine-pyridoximine-cpd3c ACHE BCHE Derivative of Amiridine Quinoline Pyridine Alkyl linked bis-ligand anti-Abeta-aggregation Multitarget
Amiridine-pyridoxamine-cpd4c ACHE BCHE Derivative of Amiridine Quinoline Pyridine Alkyl linked bis-ligand anti-Abeta-aggregation Multitarget
Cyclopentyl-pyridyl-benzoxazol-cyclopropyl-triazol-azaspiro-heptan-methanone-Cpd29 Monoglyceridelipase_lysophospholip Benzoxazol Pyridine Piperazine Triazol Azaspiro Cyclopropyl
Chlorooxazolo-pyridin-piperazin-cyclobutylcyclopropyl-pyridyl-benzoxazol-methanone-Cpd27 Monoglyceridelipase_lysophospholip Benzoxazol Pyridine Piperazine Cyclobutyl Cyclopropyl Organochlorine
Chlorooxazolo-pyridin-piperazin-cyclopentyl-pyridyl-benzoxazol-methanone-Cpd23 Monoglyceridelipase_lysophospholip Benzoxazol Pyridine Piperazine Organochlorine
FZQ-21 Epoxide_hydrolase Urea derivative Pyridine
Naphthalen-pyridin-quinuclidin-carbamate-Cpd6b BCHE Nicotinic agonist Multitarget Naphthalen Quinuclidine Azabicyclo Carbamate Pyridine
Pyridin-quinuclidin-phenylcarbamate-Cpd7a Nicotinic agonist Multitarget Quinuclidine Carbamate Pyridine Azabicyclo
A1IKD BCHE Naphthalen Pyridine Pyridazine
A1IKC BCHE Naphthalen Pyridine Pyridazine
Dimethyl-pyrazolopyridine-Ethyl-methyl-triazole-carboxylate-Cpd23 ACHE Pyridine Pyrazole Triazol GSK-3 kinase inhibitor Multitarget
AChE-Nrf2modulator-1 ACHE Pyridine Oxadiazol Nrf2 modulator Derivative of Donepezil Multitarget
HSL-IN-1 Hormone-sensitive_lipase_like Boron compound Pyridine Trifluoro
ZQ-19 Monoglyceridelipase_lysophospholip Cyanide Pyridine Sulfur compound Organochlorine
ZQ-7 Monoglyceridelipase_lysophospholip Cyanide Pyridine Sulfur compound
Benzothiazol-Phenyl-Piperazine-Pyridine-Cpd18 ACHE Benzothiazol Sulfur compound Piperazine Pyridine Fluorescent Probe
CHEMBL1688431-Cpd4e7 DPP4N_Peptidase_S9 Pyridine Cyanide Organochlorine
2,6-bis(N-methylpyridinium-3-ylmethylene)cyclohexanone-Cpd2A ACHE Bisquaternary Pyridine
CHEMBL4595876 ACHE Multitarget Pyridine Sigma1R ligand Cyanide Alkyne Benzylpiperidine Derivative of Donepezil
CHEMBL3338952 BCHE Triazol Thiadiazol Pyridine Sulfur compound
CHEMBL5176915 Monoglyceridelipase_lysophospholip Pyridine Piperidine Trifluoro
MAGL-IN-10-Cpd28 Monoglyceridelipase_lysophospholip Pyridine Piperidine Trifluoro Sulfur compound
Galantamine-benzylpyridine-C2 ACHE BCHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Pyridine Benzazepin Azepane
Emodin Natural Pyridine Acridine Not AlphaBeta Hydrolase target
Aloe-emodin-C3 ACHE Pyridine Acridine Organochlorine
CHEMBL3313966 ACHE Bisquaternary Pyridine Hydrazinylidene Organochlorine
CHEMBL4278686 ACHE GSK-3 kinase inhibitor Derivative of Tacrine Acridine Multitarget Thiazole Carboxamide Pyridine Cyclopropyl Sulfur compound
SCHEMBL5255404 Epoxide_hydrolase Pyridine
Phenyl-phenylpyridin-oxadiazol-cpd5a ACHE BCHE Oxadiazol Multitarget Pyridine
X20403 Thioesterase Pyridine Triazol Cyclopropyl Dimethoxyphenyl
X20404 Thioesterase Pyridine Triazol Dimethoxyphenyl
PyrTac-5f ACHE Derivative of Tacrine Acridine Multitarget Protein Phosphatase activator Pyridine
Tacrine-Sibiriline-Cpd7 BCHE ACHE Multitarget Acridine Derivative of Tacrine Alkyl linked bis-ligand Pyridine Carbamate Pyrrolidine Antioxidant
Pyrazolopyridine-Cpd37 Monoglyceridelipase_lysophospholip Pyridine Pyrazole
(S)Aporphine-N-benzylpyridinium ACHE Isoquinoline Pyridine Alkaloid Organochlorine
CHEMBL5206601 ACHE anti-Abeta-aggregation Multitarget Pyridine Dimethoxyphenyl
8AEV-LWU ACHE Pyridine Pyrimidine
8AM2-N0C BCHE Trimethylammonium Ammonium Pyridine Hydrazinylidene
6RKY-K7K-phosphodiester Hormone-sensitive_lipase_like Multitarget Organophosphate Pyridine Metal ion chelator
ZK8 Hormone-sensitive_lipase_like Organophosphate Pyridine Metal ion chelator
6RKY-K7K Hormone-sensitive_lipase_like Organophosphate Pyridine Metal ion chelator
CHEMBL4289712 ABHD6-Lip Triazol Pyridine
Compound-47 abh_upf0017 Pyridine Carboxamide
3-aminocoumarin-N-benzylpyridinium-9h ACHE Coumarin Pyridine Chromen
8AM1-5a BCHE Trimethylammonium Ammonium Pyridine
LF-14 ACHE Pyridine Urea derivative
Bivalent-4-Aminopyridine-12i ACHE Pyridine Alkyl linked bis-ligand
JM-20 ACHE Benzodiazepin Not AlphaBeta Hydrolase target Pyridine Multitarget 2-nitrophenyl Azepane
Coumarin-Pyridine-3f ACHE BCHE Coumarin Pyridine Chromen
Difluorophenyl-pyridin-piperazin-1,3,4-oxadiazole-49 ACHE BCHE Oxadiazol Pyridine Piperazine BACE1-inhibitor
4-aminopyridine-1,3,4-oxadiazole-9 ACHE Oxadiazol Pyridine
N-dodecyl-pyridinyl-1,3,4-thiadiazol-amine-3t ACHE Sulfur compound Pyridine Thiadiazol
5-pyrid-3-yl-1,3,4-oxadiazole-5e ACHE BCHE Oxadiazol Pyridine Organochlorine
Fragment-810 Pectinacetylesterase-Notum Pyridine Carboxamide
Fragment-872 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine
Fragment-110 Pectinacetylesterase-Notum Fragment inhibitor of Notum Urea derivative Pyridine
Sulfapyridine Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfonamide Sulfur compound Antibiotic Pyridine Not AlphaBeta Hydrolase target Benzenesulfonamide
Fragment-147 Pectinacetylesterase-Notum Fragment inhibitor of Notum Carboxamide Pyridine Not AlphaBeta Hydrolase target
Fragment-297 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzodioxo Pyridine
Fragment-197 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine Benzoate
2-N-pyridin-2-ylbenzene-1,2-diamine Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine
Maybridge_18 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine Sulfur compound
T-401 Monoglyceridelipase_lysophospholip Pyrrolidine Piperazine PET probe Pyridine Thiazole Sulfur compound
EA-4056 ACHE Carbamate Chemical Warfare Agent Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
EA-3990 ACHE Carbamate Chemical Warfare Agent Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
EA-3966 ACHE Carbamate Chemical Warfare Agent Trimethylammonium Ammonium Bisquaternary Nerve Agent Carbamate Pyridine
CHEMBL45663-49N-4Y2Q Epoxide_hydrolase Piperazine Pyridine Trifluoro
CHEMBL48137-49O-4Y2R Epoxide_hydrolase Piperazine Pyridine Cyanide Not AlphaBeta Hydrolase target Adrenergic-Receptor-ligand
VF2-Styrylpyridine-Dye Haloalkane_dehalogenase-HLD2 Pyridine Dye Fluorescent Probe Polymethine Organochlorine
thio-NAD PlaB Sulfur compound Nicotinamide Organophosphate Pyridine Purine Aminopurin
LIPG-inhib-Compound32 Lipoprotein_Lipase Pyridine Benzothiazol Sulfur compound Sulfonyl Cyclopropyl
XEN445 Lipoprotein_Lipase Pyridine Trifluoro
JVB Pectinacetylesterase-Notum Pyridine
FG1912 ACHE GSK-3 kinase inhibitor Multitarget Pyridine Piperidine Cyclopropyl Carboxamide Derivative of Donepezil
GD29 ACHE GSK-3 kinase inhibitor Multitarget Thiazole Pyridine Piperidine Cyclopropyl Carboxamide Sulfur compound Derivative of Donepezil
GT15 ACHE Derivative of Tacrine Acridine GSK-3 kinase inhibitor Sulfur compound Multitarget Carboxamide Pyridine Thiazole Cyclopropyl
BIA-10-2474 Carb_B_Chordata ABHD6-Lip Pyridine Imidazole FAAH inhibitor Multitarget Carboxamide
CHEMBL3402235 Epoxide_hydrolase Pyridine
BMS-744891 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL3112960-Cpd20d DPP4N_Peptidase_S9 Pyridine Organochlorine
CHEMBL2441952 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL1910114 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL1909991 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine
CHEMBL1910111 DPP4N_Peptidase_S9 Pyrrolidine Pyridine Organochlorine Pyrimidine
CHEMBL1234565 Epoxide_hydrolase Pyridine Nicotinamide Carboxamide Pyrazole
TAK-100 DPP4N_Peptidase_S9 Pyridine
TAK-986 DPP4N_Peptidase_S9 Pyridine
33N Epoxide_hydrolase Pyridine Nicotinamide Carboxamide
SCHEMBL7329991 Epoxide_hydrolase Pyridine
CHEMBL4451596 Epoxide_hydrolase Sulfonamide Pyridine Trifluoro Sulfur compound
3-amino-4-phenyl-pyrrolidine-15B DPP4N_Peptidase_S9 Trifluoro Pyrrolidine Pyridine Pyrimidine
MK0626 DPP4N_Peptidase_S9 Pyridine Pyrrolidine Triazol
ABC99 Pectinacetylesterase-Notum Pyridine Carbamate Organochlorine
SMR000042088 S9N_PREPL_Peptidase_S9 Pyridine Cyanide
ARI-3531 S9N_PPCE_Peptidase_S9 Pyridine Pyrrolidine Boron compound
CHEMBL1684295 Prolylcarboxypeptidase Pyrrolidine Imidazole Pyridine Oxadiazol Piperidine Benzimidazole Organochlorine
CHEMBL3086040 Prolylcarboxypeptidase Pyridine Carboxamide Morpholine
NVP-DPP728 DPP4N_Peptidase_S9 Cyanide Pyrrolidine Pyridine
ARI-3099 DPP4N_Peptidase_S9 ACPH_Peptidase_S9 Pyridine Pyrrolidine Boron compound
LEI105 Lipase_3 Pyridine Oxazole
P-10358 ACHE BCHE Carbamate Indole Pyridine
4,4-Bipyridine ACHE BCHE Pyridine
7-MEOTA-4-pyridinealdoxime ACHE Derivative of Tacrine Acridine Pyridine Pyridine-aldoxime
Dehydroevodiamine ACHE Natural Pyridine Indole beta-carboline Natural_modified Derivative of Evodiamine
Diethylparaquat ACHE Pyridinium Pyridine Herbicide
BChE-IN-21 BCHE Pyridine Quinoline Carboxamide
SB-1436 BCHE ACHE Pyridine Naphthalen Pyridinium anti-Abeta-aggregation Multitarget Organochlorine
hAChE-IN-6 BCHE ACHE Pyridine Pyrazole GSK-3 kinase inhibitor anti-tau-aggregation Multitarget Dimethoxyphenyl
Monoquat ACHE Pyridine
Morfamquat ACHE Pyridine Herbicide Morpholine
Distigmine BCHE Carbamate Stigmine Drug Pyridine
Pyridostigmine BCHE ACHE Carbamate Stigmine Drug Pyridine
RU-47213 ACHE Pyridine Organochlorine
N-Benzylpyridinium ACHE Pyridine Organochlorine
LEI104 Lipase_3 Pyridine Oxazole
Amiloride ACHE BCHE Carboxamide Drug Pyridine Not AlphaBeta Hydrolase target Organochlorine