Piperine
Alkaloid isolated from the plant Piper nigrum. It has a role as a NF-kappaB inhibitor, a plant metabolite, a food component and a human blood serum metabolite. Piperine and its isomer chavicine, is the alkaloid responsible for the pungency of black pepper and long pepper
General
Type : Fragment inhibitor of Notum, Piperidine, Natural, Benzodioxo
Chemical_Nomenclature : (2E,4E)-5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpenta-2,4-dien-1-one
Canonical SMILES : C1CCN(CC1)C(=O)C=CC=CC2=CC3=C(C=C2)OCO3
InChI : InChI=1S\/C17H19NO3\/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15\/h2-3,6-9,12H,1,4-5,10-11,13H2\/b6-2+,7-3+
InChIKey : MXXWOMGUGJBKIW-YPCIICBESA-N
Other name(s) : 1-Piperoylpiperidine || Piperin || Bioperine
MW : 285.34
Formula : C17H19NO3
CAS_number : 94-62-2
PubChem : 638024
UniChem : MXXWOMGUGJBKIW-YPCIICBESA-N
Wikipedia : Piperine
Target
Families : Piperine ligand of proteins in family
Pectinacetylesterase-Notum
Structure :
7BLW
Protein :
human-NOTUM
References
No reference