Fragment inhibitor of Notum

General

Custom-designed acid fragment library used to identify inhibitors of Notum carboxylesterase activity. The compounds analyzed in structures are not necessarily specific or good inhibitors
Inhibitor Main targeted enzyme families Type Structure
ARUK3004048 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole
ARUK3004903 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole
ARUK3004308 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole
ARUK3004558 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole
ARUK3004470 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole
ARUK3004552 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole
ARUK3004556 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole
ARUK3005522 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole
ARUK3005518 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole
ARUK3004876 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole Trifluoro
ARUK3004877 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole
ARUK3006560 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole Trifluoro
ARUK3006561 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole Trifluoro
ARUK3006562 Pectinacetylesterase-Notum Fragment inhibitor of Notum Indole Trifluoro
ARUK3003778 Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Triazol
ARUK3000438 Pectinacetylesterase-Notum Fragment inhibitor of Notum Triazol Trifluoro
CHEMBL57478 Pectinacetylesterase-Notum Fragment inhibitor of Notum Piperidine Indole
ARUK3001043 Pectinacetylesterase-Notum Fragment inhibitor of Notum Triazol Trifluoro
ARUK3002697 Pectinacetylesterase-Notum Fragment inhibitor of Notum Triazol Pyridazine Sulfur Compound
ARUK3003934 Pectinacetylesterase-Notum Fragment inhibitor of Notum Triazol Pyridazine Sulfur Compound
Fragment-823 Fragment inhibitor of Notum Pyrimidine
Fragment-828 Pectinacetylesterase-Notum Fragment inhibitor of Notum Urea derivative
Fragment-872 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine
Fragment-863 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyrazole
Fragment-791 Pectinacetylesterase-Notum Fragment inhibitor of Notum Carboxamide
Fragment-772 Pectinacetylesterase-Notum Fragment inhibitor of Notum
Fragment-784 Pectinacetylesterase-Notum Fragment inhibitor of Notum
Fragment-792 Pectinacetylesterase-Notum Fragment inhibitor of Notum Cyanide
Fragment-705 Pectinacetylesterase-Notum Fragment inhibitor of Notum Morpholine
Fragment-722 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyrrolidine
Fragment-714 Pectinacetylesterase-Notum Fragment inhibitor of Notum Morpholine Naphthalen
Fragment-658 Pectinacetylesterase-Notum Fragment inhibitor of Notum Hydrazide
Fragment-690 Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound
Fragment-923 Pectinacetylesterase-Notum Fragment inhibitor of Notum Tetrazol
Fragment-924 Pectinacetylesterase-Notum Fragment inhibitor of Notum
Fragment-900 Pectinacetylesterase-Notum Fragment inhibitor of Notum
Fragment-916 Pectinacetylesterase-Notum Fragment inhibitor of Notum Carboxamide
Fragment-934 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzimidazole
Fragment-955 Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Thiadiazol
Fragment-927 Pectinacetylesterase-Notum Fragment inhibitor of Notum Piperazine
ARUK3000223 Pectinacetylesterase-Notum Fragment inhibitor of Notum Trifluoro Triazol
Fragment-886 Pectinacetylesterase-Notum Fragment inhibitor of Notum Piperidine Pyrazole
Fragment-067 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyrimidine Pyrazole
Fragment-074 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzoate
Fragment-077 Pectinacetylesterase-Notum Fragment inhibitor of Notum Triazol
Fragment-065 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzimidazole
Fragment-154 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzimidazole Cyanide
Fragment-159 Pectinacetylesterase-Notum Fragment inhibitor of Notum
Felbinac Pectinacetylesterase-Notum Fragment inhibitor of Notum Drug Not A\/B H target
Fragment-174 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyrazole
Fragment-173 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzimidazole Cyanide
Fragment-110 Pectinacetylesterase-Notum Fragment inhibitor of Notum Urea derivative Pyridine
Sulfapyridine Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfonamide Sulfur Compound Antibiotic Pyridine Not A\/B H target Benzenesulfonamide
Fragment-147 Pectinacetylesterase-Notum Fragment inhibitor of Notum Carboxamide Pyridine Not A\/B H target
Fragment-297 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzodioxo Pyridine
Fragment-290 Pectinacetylesterase-Notum Fragment inhibitor of Notum Acetanilide
Fragment-201 Pectinacetylesterase-Notum Fragment inhibitor of Notum Piperidine Oxadiazol
Fragment-210 Pectinacetylesterase-Notum Fragment inhibitor of Notum
Fragment-283 Pectinacetylesterase-Notum Fragment inhibitor of Notum
Fragment-282 Pectinacetylesterase-Notum Fragment inhibitor of Notum
Fragment-277 Pectinacetylesterase-Notum Fragment inhibitor of Notum Piperazine Cyanide
Fragment-276 Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Thiadiazol
Fragment-197 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine Benzoate
Fragment-193 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyrazole
Fragment-199 Pectinacetylesterase-Notum Fragment inhibitor of Notum Morpholine
Fragment-588 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzyloxycarbonyl Carbamate
Fragment-609 Pectinacetylesterase-Notum Fragment inhibitor of Notum Thiomorpholine
Fragment-634 Pectinacetylesterase-Notum Fragment inhibitor of Notum Cyanide Piperidine
Fragment-646 Pectinacetylesterase-Notum Fragment inhibitor of Notum Benzodioxo
Fragment-830 Pectinacetylesterase-Notum Fragment inhibitor of Notum
2-N-pyridin-2-ylbenzene-1,2-diamine Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine
1-Naphthalenepentanoic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Naphthalen
2-(1,2-Dihydroacenaphthylen-5-ylsulfanyl)acetic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Naphthalen Sulfur Compound
N-methyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxamide Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Carboxamide Carbamate
3-(Quinazolin-4-ylthio)propanoic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Quinazoline
(Isoquinolin-1-ylsulfanyl)-acetic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Isoquinoline Quinoline Sulfur Compound
Riluzole Pectinacetylesterase-Notum Drug Benzothiazol Trifluoro Sulfur Compound Not A\/B H target Fragment inhibitor of Notum
ARUK3003710 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyrazole
(4-fluoroanilino)thiourea Pectinacetylesterase-Notum Fragment inhibitor of Notum Urea derivative Sulfur Compound
Methyl-4H-thieno[3,2-c]chromene-2-carboxylic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Chromen
4H-thieno[3,2-c]chromene-2-carboxylic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Chromen
Piperine Pectinacetylesterase-Notum Fragment inhibitor of Notum Piperidine Natural Benzodioxo
Maybridge_18 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridine Sulfur Compound
Maybridge_4 Pectinacetylesterase-Notum Fragment inhibitor of Notum Hydrazide Oxadiazol tert-Butyl
Maybridge_56 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridazine
ARUK3003902 Pectinacetylesterase-Notum Fragment inhibitor of Notum Triazol Pyridazine Sulfur Compound
ARUK3003909 Pectinacetylesterase-Notum Fragment inhibitor of Notum Triazol Trifluoro Pyridazine Sulfur Compound
ARUK3003776 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridazine Triazol Azabicyclo Sulfur Compound
ARUK3003775 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridazine Triazol Sulfur Compound
ARUK3003748 Pectinacetylesterase-Notum Fragment inhibitor of Notum Pyridazine Triazol Sulfur Compound
Fragment-063-notum-screen Pectinacetylesterase-Notum Urea derivative Fragment inhibitor of Notum Benzoxadiazole
Fragment-064-notum-screen Pectinacetylesterase-Notum Urea derivative Fragment inhibitor of Notum Sulfur Compound
Fragment-049-notum-screen Pectinacetylesterase-Notum Urea derivative Fragment inhibitor of Notum