human-NOTUM

No mutation

4UYU - Structure of the human wnt deacetylase notum - Crystal form I iodide complex - 2.3A 4UYW - Structure of the human wnt deacetylase notum - Crystal form I heparin complex - 1.7A 4UYZ - Structure of the human wnt deacetylase notum - Crystal form II - 2.8A 4UZ1 - Structure of the wnt deacetylase notum - Crystal form III - 1.4A 4UZ5 - Structure of the human wnt deacetylase notum - Crystal form IV - 2.1A 4UZ6 - Structure of the human wnt deacetylase notum - Crystal form V SOS complex - 1.9A 4UZ7 - Structure of the human wnt deacetylase notum - Crystal form VI - 2.2A 4UZ9 - Structure of the human wnt deacetylase notum - Crystal form VII SOS complex - 2.2A 4UZA - Structure of the human wnt deacetylase notum - Crystal form VIII - Phosphate complex 2.4A 4UZL - Structure of the wnt deacetylase notum - Crystal form I myristoleate complex 2.1A 4UZQ - Structure of th humane wnt deacetylase notum in complex with O-Palmitoleoyl serine- Crystal form IX - 1.5A 4WBH - Structure of the human wnt deacetylase notum - Crystal form I Apo - 2.2A 6R8P - Structure of the human Wnt deacetylase notum with inhibitor fragment 723 JVB Pyridine 6R8Q - Structure of the human Wnt deacylase Notum in complex with a benzotriazole fragment JV5 6R8R - Structure of the human Wnt deacylase Notum in complex with isoquinoline 45 JV8 6T2H - Furano[2,3-d]prymidine amides as human Notum inhibitors 1 (M9N) 6T2K - Furano[2,3-d]prymidine amides as human Notum inhibitors 2 (LP-922056) 6TR5 - Melatonin-human Notum complex 6TR6 - N-acetylserotonin- humanNotum complex 6TR7 - Structure of the human Wnt deacylase Notum in complex with N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide (6QCQ withdrawn) 6TUZ - Theophylline- human Notum complex 6TV4 - Caffeine- human Notum complex 6YSK - 1-phenylpyrroles and 1-enylpyrrolidines as inhibitors of human Notum 6YUW - Structure of the human Wnt deacylase Notum in complex with a pyrrole-3-carboxylic acid fragment 454 6YUY - Structure of the human Wnt deacylase Notum in complex with a pyrrole-3-carboxylic acid fragment 471 6YV0 - Structure of the human Wnt deacylase Notum in complex with a pyrrolidine-3-carboxylic acid fragment 587 6YV2 - Structure of the human Wnt deacylase Notum in complex with a pyrrolidine-3-carboxylic acid fragment 598 6YV4 - Structure of the human Wnt deacylase Notum in complex with a pyrrole-3-carboxylic acid fragment 454 6YXI - Structure of human Notum in complex with a 1-(3-Chlorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid inhibitor 6ZUV - Structure of the human Wnt deacylase Notum in complex with fragment 286 (Compound 7, 4F-329S) 6ZVL - Structure of the human Wnt deacylase Notum in complex with SCHEMBL21776992 (ARUK3000263 Compound23dd 7a) 6ZYF - Human Notum (S232A) inactive mutant Ghrelin complex 7ARG - Human Notum in complex with ARUK3002704 compound 1 Methyl- 7B2V - Human Notum in complex with ARUK3003906 compound 3\; ethyl- 7B2Y - Human Notum in complex with ARUK3003910 compound 4\; 2,2 difluoroethyl- 7B2Z - Human Notum in complex with ARUK3003907 compound 6\; iso-propanol 7B37 - Human Notum in complex with ARUK3003718 compound 2 acid 7B3F - Human Notum S232A in complex with ARUK3003718 compound 2 acid 7B3G - Human Notum in complex with ARUK3003902 7B3H - Human Notum in complex with ARUK3003909 7B3I - Human Notum in complex with ARUK3003776 7B3P - Human Notum in complex with ARUK3003775 7B3X - Human Notum in complex with ARUK3003748 7B45 - Human Notum in complex with ARUK3003934 7B4X - Human Notum in complex with ARUK3002697 7B50 - Human Notum in complex with ARUK3003778 7B7W - Structure of the human Wnt deacylase Notum in complex with fragment 049 7B7X - Structure of the human Wnt deacylase Notum in complex with fragment 063 7B7Y - Structure of the human Wnt deacylase Notum in complex with fragment 064 7B84 - Structure of the human Wnt deacylase Notum in complex with fragment 065 7B86 - Structure of the human Wnt deacylase Notum in complex with fragment 067 7B87 - Structure of the human Wnt deacylase Notum in complex with fragment 074 7B89 - Structure of the human Wnt deacylase Notum in complex with fragment 077 7B8A - Structure of the human Wnt deacylase Notum in complex with fragment 110 7B8C - Structure of the human Wnt deacylase Notum in complex with fragment 147 7B8D - Structure of the human Wnt deacylase Notum in complex with (fragment 151) Sulfapyridine 7B8F - Structure of the human Wnt deacylase Notum in complex with fragment 154 7B8G - Structure of the human Wnt deacylase Notum in complex with fragment 159 7B8J - Structure of the human Wnt deacylase Notum in complex with fragment 163 Felbinac 7B8K - Structure of the human Wnt deacylase Notum in complex with fragment 173 7B8L - Structure of the human Wnt deacylase Notum in complex with fragment 174 7B8M - Structure of the human Wnt deacylase Notum in complex with fragment 193 7B8N - Structure of the human Wnt deacylase Notum in complex with fragment 197 7B8O - Structure of the human Wnt deacylase Notum in complex with fragment 199 7B8U - Structure of the human Wnt deacylase Notum in complex with fragment 201 7B8X - Structure of the human Wnt deacylase Notum in complex with fragment 210 7B8Y - Structure of the human Wnt deacylase Notum in complex with fragment 276 7B8Z - Structure of the human Wnt deacylase Notum in complex with fragment 277 7B98 - Structure of the human Wnt deacylase Notum in complex with fragment 282 7B99 - Structure of the human Wnt deacylase Notum in complex with fragment 283 7B9D - Structure of the human Wnt deacylase Notum in complex with fragment 290 7B9I - Structure of the human Wnt deacylase Notum in complex with fragment 297 7B9N - Structure of the human Wnt deacylase Notum in complex with fragment 588 7B9U - Structure of the human Wnt deacylase Notum in complex with fragment 609 7BA1 - Structure of the human Wnt deacylase Notum in complex with fragment 634 7BAC - Structure of the human Wnt deacylase Notum in complex with fragment 646 7BAP - Structure of the human Wnt deacylase Notum in complex with fragment 648 7BC8 - Structure of the human Wnt deacylase Notum in complex with fragment 658 7BC9 - Structure of the human Wnt deacylase Notum in complex with fragment 690 7BCC - Structure of the human Wnt deacylase Notum in complex with fragment 705 7BCD - Structure of the human Wnt deacylase Notum in complex with fragment 714 7BCE - Structure of the human Wnt deacylase Notum in complex with fragment 718 7BCF - Structure of the human Wnt deacylase Notum in complex with fragment 722 7BCH - Structure of the human Wnt deacylase Notum in complex with fragment 772 7BCI - Structure of the human Wnt deacylase Notum in complex with fragment 784 7BCK - Structure of the human Wnt deacylase Notum in complex with fragment 791 7BCL - Structure of the human Wnt deacylase Notum in complex with fragment 792 7BD2 - Structure of the human Wnt deacylase Notum in complex with fragment 810 7BD3 - Structure of the human Wnt deacylase Notum in complex with fragment 823 7BD4 - Structure of the human Wnt deacylase Notum in complex with fragment 828 7BD5 - Structure of the human Wnt deacylase Notum in complex with fragment 830 7BD6 - Structure of the human Wnt deacylase Notum in complex with fragment 863 7BD8 - Structure of the human Wnt deacylase Notum in complex with fragment 872 7BD9 - Structure of the human Wnt deacylase Notum in complex with fragment 886 7BDA - Structure of the human Wnt deacylase Notum in complex with fragment 900 7BDB - Structure of the human Wnt deacylase Notum in complex with fragment 916 7BDC - Structure of the human Wnt deacylase Notum in complex with fragment 923 7BDD - Structure of the human Wnt deacylase Notum in complex with fragment 924 7BDF - Structure of the human Wnt deacylase Notum in complex with fragment 927 7BDG - Structure of the human Wnt deacylase Notum in complex with fragment 934 7BDH - Structure of the human Wnt deacylase Notum in complex with fragment 955 7BLI - Notum-Bepridil complex 7BLS - Human Notum-maybridge_18 7BLT - Human Notum-maybridge_4 7BLU - Human Notum-maybridge_56 7BLW - Human Notum_Piperine complex 7BM1 - Human Notum_Valsartan complex 7BM3 - Human Notum Rosmarinic acid complex 7BM7 - Human Notum complexed with fragment 5e, 1-Naphthalenepentanoic acid 7BMB - Human Notum PPOH complex 7BMD - Human Notum TDZD8 complex 7BN5 - Human Notum comlexed with fragment_1 (2-(isoquinolin-1-ylsulfanyl)acetic acid) 7BN8 - Human Notum complexed with fragment_3 (4H,5H-naphtho[1,2-b]thiophene-2-carboxylic acid) 7BNB - Human Notum comlexed with fragment_50 (3-(quinazolin-4-ylsulfanyl)propanoic acid) 7BNC - Human Notum complexed with fragment_126 (2-(1,2-dihydroacenaphthylen-5-ylsulfanyl)acetic acid) 7BND - Human Notum complexed with Fragment41 (N-methyl-4,5-dihydronaphtho,2-bthiophene-2-carboxamide) 7BNE - Human Notum complexed with Nicotine 7BNF - Human Notum comlexed with Cotinine 7BNJ - Human Notum complexed with Riluzole 7BNL - Human Notum ARUK3003710 7BO1 - Human Notum complexed with Fragment_274 [(4-fluorophenyl)amino]thiourea ((4-fluoroanilino)thiourea) 7BO2 - Human Notum complexed with Fragment_130 (4H-thieno[3,2-c]chromene-2-carboxylic acid) 7BO5 - Human Notum complexed with Fragment_130_methyEster (methyl 4H-thieno[3,2-c]chromene-2-carboxylate) 7PJR - Structure of the human Wnt deacylase Notum in complex with ARUK3000438 7PK3 - Structure of the human Wnt deacylase Notum in complex with ARUK3001185 7PKV - Structure of the human Wnt deacylase Notum in complex with ARUK3000223 Compound 7b 7QVZ - Structure of the human Wnt deacylase Notum in complex with ARUK3001043 8BSP - Structure of the human Wnt deacylase Notum in complex with ARUK3006560 8BSQ - Structure of the human Wnt deacylase Notum in complex with ARUK3006561 8BSR - Structure of the human Wnt deacylase Notum in complex with ARUK3006562 8BSZ - Structure of the human Wnt deacylase Notum in complex with ARUK3005522 8BT0 - Structure of the human Wnt deacylase Notum in complex with ARUK3005518 8BT2 - Structure of the human Wnt deacylase Notum in complex with ARUK3004876 8BT5 - Structure of the human Wnt deacylase Notum in complex with ARUK3004877 8BT7 - Structure of the human Wnt deacylase Notum in complex with ARUK3004903 8BT8 - Structure of the human Wnt deacylase Notum in complex with ARUK3004048 8BTA - Structure of the human Wnt deacylase Notum in complex with ARUK3004308 8BTC - Structure of the human Wnt deacylase Notum in complex with ARUK3004558 8BTE - Structure of the human Wnt deacylase Notum in complex with ARUK3004470 8BTH - Structure of the human Wnt deacylase Notum in complex with ARUK3004552 8BTI - Structure of the human Wnt deacylase Notum in complex with ARUK3004556

No kinetic

No disease

Myristic-acid O-palmitoleoyl-L-serine OPTS Octanoyl-ghrelin Paranitrophenyl-octanoate Paranitrophenylacetate Paranitrophenylbutyrate

(4-fluoroanilino)thiourea (Isoquinolin-1-ylsulfanyl)-acetic-acid 1-Naphthalenepentanoic-acid 2-(1,2-Dihydroacenaphthylen-5-ylsulfanyl)acetic-acid 2-N-pyridin-2-ylbenzene-1,2-diamine 3-(Quinazolin-4-ylthio)propanoic-acid 4,5-Dihydronaphtho[1,2-b]thiophene-2-carboxylic-acid 4F-329S 4H-thieno[3,2-c]chromene-2-carboxylic-acid ABC99 ARUK3000223 ARUK3000438 ARUK3001043 ARUK3001185 ARUK3002697 ARUK3002704 ARUK3003710 ARUK3003718 ARUK3003748 ARUK3003775 ARUK3003776 ARUK3003778 ARUK3003902 ARUK3003906 ARUK3003907 ARUK3003909 ARUK3003910 ARUK3003934 ARUK3004048 ARUK3004308 ARUK3004470 ARUK3004552 ARUK3004556 ARUK3004558 ARUK3004876 ARUK3004877 ARUK3004903 ARUK3005518 ARUK3005522 ARUK3006560 ARUK3006561 ARUK3006562 Benzotriazole-39-JV5 Bepridil CHEMBL4539054 CHEMBL57478 Caffeine Cotinine Decanoate Felbinac Fragment-049-notum-screen Fragment-063-notum-screen Fragment-064-notum-screen Fragment-065 Fragment-067 Fragment-074 Fragment-077 Fragment-110 Fragment-147 Fragment-154 Fragment-159 Fragment-173 Fragment-174 Fragment-193 Fragment-197 Fragment-199 Fragment-201 Fragment-210 Fragment-276 Fragment-277 Fragment-282 Fragment-283 Fragment-290 Fragment-297 Fragment-588 Fragment-609 Fragment-634 Fragment-646 Fragment-658 Fragment-690 Fragment-705 Fragment-714 Fragment-722 Fragment-772 Fragment-784 Fragment-791 Fragment-792 Fragment-810 Fragment-828 Fragment-830 Fragment-863 Fragment-872 Fragment-886 Fragment-900 Fragment-916 Fragment-923 Fragment-924 Fragment-927 Fragment-934 Fragment-955 Heparin-disaccharide Isoquinoline-45-JV8 JVB LP-914822 LP-922056 LP-935001 Laurate M9N Maybridge_18 Maybridge_4 Maybridge_56 Melatonin Methyl-4H-thieno[3,2-c]chromene-2-carboxylic-acid Myristic-acid Myristoleic-acid N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide N-acetylserotonin N-methyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxamide Nicotine Octanoate PMSF PPOH Palmitoleic-acid Piperine Pyrrole-20i-6YXI Pyrrole-26-6YSK Pyrrole-5-6YUY Pyrrole-6-6YV4 Pyrrole-7-6YUW Pyrrolidine-10-6YV0 Pyrrolidine-8-6YV2 Riluzole SCHEMBL21776992 Sucrose-octasulfate Sulfapyridine TDZD8 Theophylline Valsartan

AB062438 AC145207 BC036872 BC060882

C9JYG8 K7EIG3 Q6P988

C9JYG8 K7EIG3 Q6P988

C9JYG8 K7EIG3 Q6P988

C9JYG8 K7EIG3 Q6P988

C9JYG8 K7EIG3 Q6P988