Polyozellin
IC50 0.77 mcroM human-PREP
General
Type : Natural
Chemical_Nomenclature : (12-acetyloxy-6,7,16,17-tetrahydroxy-3,20-dioxapentacyclo[11.7.0.02,10.04,9.014,19]icosa-1(13),2(10),4,6,8,11,14,16,18-nonaen-11-yl) acetate
Canonical SMILES : CC(=O)OC1=C(C2=C(C3=C1C4=CC(=C(C=C4O3)O)O)OC5=CC(=C(C=C52)O)O)OC(=O)C
InChI : InChI=1S\/C22H14O10\/c1-7(23)29-19-17-9-3-11(25)13(27)5-15(9)31-21(17)22-18(20(19)30-8(2)24)10-4-12(26)14(28)6-16(10)32-22\/h3-6,25-28H,1-2H3
InChIKey : NOBAAHRLFGFAOS-UHFFFAOYSA-N
Other name(s) : B7DFS96VZB, UNII-B7DFS96VZB, SC-670123, CHEMBL4214751
MW : 438.3
Formula : C22H14O10
CAS_number : 197703-46-1
PubChem : 145972991
UniChem : NOBAAHRLFGFAOS-UHFFFAOYSA-N
Target
Families : Polyozellin ligand of proteins in family
S9N_PPCE_Peptidase_S9
Protein :
human-PREP
References (2)
| Title : Synthesis of polyozellin, a prolyl oligopeptidase inhibitor, and its structural revision - Takahashi_2018_Bioorg.Med.Chem.Lett_28_930 |
| Author(s) : Takahashi S , Kawano T , Nakajima N , Suda Y , Usukhbayar N , Kimura KI , Koshino H |
| Ref : Bioorganic & Medicinal Chemistry Lett , 28 :930 , 2018 |
| PubMedID: 29429833 |
| Gene_locus related to this paper: human-PREP |