Prenylated-Arylidene-thiazolidine-Cpd22b
Compound 22b IC50 human-PNLIP 6.18 +/- 0.46 microM
General
Type : Thiazolidine, Thiazole, Sulfur Compound
Chemical_Nomenclature : 5-{[3-methoxy-4-(3-methylbut-2-enyloxy)phenyl]methyl}-3-[(4-methylphenyl)methyl]-1,3-thiazolidine-2,4-dione
Canonical SMILES : C1=C(C(=CC(=C1)CC2C(N(C(S2)=O)CC3=CC=C(C=C3)C)=O)OC)OCC=C(C)C
InChI : InChI=1S\/C24H27NO4S\/c1-16(2)11-12-29-20-10-9-19(13-21(20)28-4)14-22-23(26)25(24(27)30-22)15-18-7-5-17(3)6-8-18\/h5-11,13,22H,12,14-15H2,1-4H3
InChIKey : DAGPWGSLOUVBAO-UHFFFAOYSA-N
Other name(s) : 5-{[3-Methoxy-4-(3-methyl-2-butenyloxy)phenyl]methyl}-3-[(p-tolyl)methyl]-1,3-thiazolidine-2,4-dione || Compound 22b
Target
Families : Prenylated-Arylidene-thiazolidine-Cpd22b ligand of proteins in family
Pancreatic_lipase
Protein :
human-PNLIP
References (1)
| Title : Design, Synthesis, and Pharmacological Evaluation of Prenylated Arylidene-Substituted Thiazolidinedione-Based Pancreatic Lipase Inhibitors as Anti-obesity Agents - Khator_2025_Arch.Pharm.(Weinheim)_358_e70135 |
| Author(s) : Khator R , Jagtap UA , Lavanya B , Paul AT , Monga V |
| Ref : Arch Pharm (Weinheim) , 358 :e70135 , 2025 |
| Abstract : |
| PubMedSearch : Khator_2025_Arch.Pharm.(Weinheim)_358_e70135 |
| PubMedID: 41214857 |