RDP
. Dichlorvos: human-CES1 IC50 15.95 [nM] Cao et al. 2026
General
Type : Organophosphorus flame retardant plasticizer, Organophosphate, Plasticizer
Chemical_Nomenclature : (3-diphenoxyphosphoryloxyphenyl) diphenyl phosphate
Canonical SMILES : C1=CC=C(C=C1)OP(=O)(OC2=CC=CC=C2)OC3=CC(=CC=C3)OP(=O)(OC4=CC=CC=C4)OC5=CC=CC=C5
InChI : InChI=1S\/C30H24O8P2\/c31-39(33-25-14-5-1-6-15-25,34-26-16-7-2-8-17-26)37-29-22-13-23-30(24-29)38-40(32,35-27-18-9-3-10-19-27)36-28-20-11-4-12-21-28\/h1-24H
InChIKey : OWICEWMBIBPFAH-UHFFFAOYSA-N
Other name(s) : Resorcinol bis(diphenyl phosphate) || Fyrolflex RDP || Mark PFK || Phosphoric acid, 1,3-phenylene tetraphenyl ester || SCHEMBL78015
MW : 574.5
Formula : C30H24O8P2
CAS_number : 57583-54-7
PubChem : 93311
UniChem : OWICEWMBIBPFAH-UHFFFAOYSA-N
Target
Families : RDP ligand of proteins in family
Carb_B_Chordata
Protein :
human-CES1
References (2)
| Title : Structure-dependent inhibition of human carboxylesterase 1 by organophosphate esters: integrated in vitro profiling and 3D-QSAR interpretation - Cao_2026_Chem.Biol.Interact__112149 |
| Author(s) : Cao Z , Men S , Li Z , Liu G , Su Q , Chen X , Che X , Jin H |
| Ref : Chemico-Biological Interactions , :112149 , 2026 |
| Abstract : |
| PubMedSearch : Cao_2026_Chem.Biol.Interact__112149 |
| PubMedID: 42203055 |
| Gene_locus related to this paper: human-CES1 |
| Title : Phosphorus flame retardants: properties, production, environmental occurrence, toxicity and analysis - van der Veen_2012_Chemosphere_88_1119 |
| Author(s) : van der Veen I , De Boer J |
| Ref : Chemosphere , 88 :1119 , 2012 |
| Abstract : |
| PubMedSearch : van der Veen_2012_Chemosphere_88_1119 |
| PubMedID: 22537891 |