Tri(indolyl)methane-Cpd6b
CES2 IC50 0.34 +/- 0.02 microM Ki 0.08 microM Mixed
General
Type : Indole
Chemical_Nomenclature : 3-[1H-indol-3-yl-(1-methylindol-3-yl)methyl]-1-methylindole
Canonical SMILES : CN1C=C(C2=CC=CC=C21)C(C3=CNC4=CC=CC=C43)C5=CN(C6=CC=CC=C65)C
InChI : InChI=1S\/C27H23N3\/c1-29-16-22(19-10-4-7-13-25(19)29)27(21-15-28-24-12-6-3-9-18(21)24)23-17-30(2)26-14-8-5-11-20(23)26\/h3-17,27-28H,1-2H3
InChIKey : SUWGIKIBVWFMPP-UHFFFAOYSA-N
Other name(s) :
methane-Cpd6b.gif)
Target
Families : Tri(indolyl)methane-Cpd6b ligand of proteins in family
Carb_B_Chordata
Protein :
human-CES2
References (1)
| Title : Discovery of tri(indolyl)methanes as potent and selective inhibitors against human carboxylesterase 2 - Li_2025_Int.J.Biol.Macromol_307_141868 |
| Author(s) : Li WR , Mu J , Wang AQ , Su QL , Li MH , Lu CW , Zou LW |
| Ref : Int J Biol Macromol , 307 :141868 , 2025 |
| Abstract : |
| PubMedSearch : Li_2025_Int.J.Biol.Macromol_307_141868 |
| PubMedID: 40068745 |
| Gene_locus related to this paper: human-CES2 |