Triazole-tethered-benzothiazole-cpd10f
IC50 0.10 +/- 0.04 microM
General
Type : Triazol, Benzothiazol, Sulfur Compound, Multitarget, Thiazole
Chemical_Nomenclature :
Canonical SMILES : C1=CC=C4C(=C1)N=C(N=C(C[N]3C=C(COC(\/C(=C([H])\/C2=CC=C(C=C2)[N](=O)=O)[H])=O)N=N3)O[H])S4
InChI : InChI=1S\/C21H16N6O5S\/c28-19(23-21-22-17-3-1-2-4-18(17)33-21)12-26-11-15(24-25-26)13-32-20(29)10-7-14-5-8-16(9-6-14)27(30)31\/h1-11H,12-13H2,(H,22,23,28)\/b10-7+
InChIKey : SOWOYAOOBWBXED-JXMROGBWSA-N
Other name(s) : Compound 10f
Target
References (3)
| Title : Click Chemistry-Aided Synthesis of Triazole-Tethered Benzothiazoles as Novel Multifunctional Agents Against Alzheimer's Disease - Elbadawi_2025_Arch.Pharm.(Weinheim)_358_e70046 |
| Author(s) : Elbadawi MM , Elgazar AA , Hefny AA , Abdulla MH , Bin Traiki T , Roshdy E , Al-Sanea MM , Abe M , Eldehna WM , Rao PPN , Hamdi A |
| Ref : Arch Pharm (Weinheim) , 358 :e70046 , 2025 |
| Abstract : |
| PubMedSearch : Elbadawi_2025_Arch.Pharm.(Weinheim)_358_e70046 |
| PubMedID: 40641142 |
| Title : Click Chemistry-Aided Synthesis of Triazole-Tethered Benzothiazoles as Novel Multifunctional Agents Against Alzheimer's Disease - Elbadawi_2025_Arch.Pharm.(Weinheim)_358_e70046 |
| Author(s) : Elbadawi MM , Elgazar AA , Hefny AA , Abdulla MH , Bin Traiki T , Roshdy E , Al-Sanea MM , Abe M , Eldehna WM , Rao PPN , Hamdi A |
| Ref : Arch Pharm (Weinheim) , 358 :e70046 , 2025 |
| Abstract : |
| PubMedSearch : Elbadawi_2025_Arch.Pharm.(Weinheim)_358_e70046 |
| PubMedID: 40641142 |
| Title : Click Chemistry-Aided Synthesis of Triazole-Tethered Benzothiazoles as Novel Multifunctional Agents Against Alzheimer's Disease - Elbadawi_2025_Arch.Pharm.(Weinheim)_358_e70046 |
| Author(s) : Elbadawi MM , Elgazar AA , Hefny AA , Abdulla MH , Bin Traiki T , Roshdy E , Al-Sanea MM , Abe M , Eldehna WM , Rao PPN , Hamdi A |
| Ref : Arch Pharm (Weinheim) , 358 :e70046 , 2025 |
| Abstract : |
| PubMedSearch : Elbadawi_2025_Arch.Pharm.(Weinheim)_358_e70046 |
| PubMedID: 40641142 |