ZT-1
precusor of huperzineA rapidly hydrolised
General
Type : Derivative of Huperzine
Chemical_Nomenclature : (5R,9R)-5-(r-chloro-2-hydroxy-3-methoxybenzylidene-amino)-11-ethlidene-7-methyl-1,2,5,6,9,10-hexahydro-5,9-methanocycloocta[b]pyridin-2-one
Canonical SMILES : CC=C1C2CC3=C(C1(CC(=C2)C)NC=C4C=C(C=C(C4=O)OC)Cl)C=CC(=O)N3
InChI : InChI=1S\/C23H23ClN2O3\/c1-4-17-14-7-13(2)11-23(17,18-5-6-21(27)26-19(18)9-14)25-12-15-8-16(24)10-20(29-3)22(15)28\/h4-8,10,12,14,25H,9,11H2,1-3H3,(H,26,27)\/b15-12-,17-4+
InChIKey : GYTJFKCCTYZWGL-WQOXWKGMSA-N
Other name(s) : ZT1 || Mimopezil || UNII-4MU6P880QL || Xipulin || Mimopezil [INN]
MW : 426.94
Formula : C24H27ClN2O3
CAS_number :
PubChem : 44153604
UniChem : GYTJFKCCTYZWGL-WQOXWKGMSA-N
References (2)
| Title : Simultaneous determination of ZT-1 and its metabolite Huperzine A in plasma by high-performance liquid chromatography with ultraviolet detection - Wei_2006_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_830_120 |
| Author(s) : Wei G , Xiao S , Lu R , Liu C |
| Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 830 :120 , 2006 |
| Abstract : |
| PubMedSearch : Wei_2006_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_830_120 |
| PubMedID: 16288904 |
| Title : A sensitive method for the determination of the novel cholinesterase inhibitor ZT-1 and its active metabolite huperzine A in rat blood using liquid chromatography\/tandem mass spectrometry - Li_2004_Rapid.Commun.Mass.Spectrom_18_651 |
| Author(s) : Li C , Du F , Yu C , Xu X , Zheng J , Xu F , Zhu D |
| Ref : Rapid Commun Mass Spectrom , 18 :651 , 2004 |
| Abstract : |
| PubMedSearch : Li_2004_Rapid.Commun.Mass.Spectrom_18_651 |
| PubMedID: 15052575 |