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Derivative of Huperzine

General

Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata. Inhibitor of cholinesterases used also as building block for multitarget compounds
Inhibitor Main targeted enzyme families Type Structure
Levetiracetam-huprine-hybrid-Cpd10 ACHE BCHE Pyrrolidine Multitarget Derivative of Huperzine Alkyl linked bis-ligand
Huptremule-D ACHE Octahydroazulenofuran Derivative of Huperzine Natural Alkaloid
Huptremule-C ACHE Octahydroazulenofuran Alkaloid Natural Derivative of Huperzine
Huptremule-A ACHE Alkaloid Natural Derivative of Huperzine
Lycocasuarine-C ACHE Derivative of Huperzine Natural Alkaloid
Lycocasuarinine-D ACHE Derivative of Huperzine Natural Alkaloid
N-demethylhuperzinine BCHE ACHE Derivative of Huperzine Natural Alkaloid
3,5-dihydroxybenzamido-huprine-hybrid-11 BCHE ACHE Multitarget Derivative of Huperzine BACE1-inhibitor Alkyl linked bis-ligand Organochlorine
K-1234 ACHE Derivative of Huperzine Derivative of Tacrine Acridine
8U2-7AIX7AY-compound5i ACHE BCHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Triazol Organochlorine
8U5-7AIW-compound5g ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UE-7AIV-compound5f ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UQ-7AIU-compound5d ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UK-7AIT-compound5c ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UH-7AIS-compound5b ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
E1N ACHE Derivative of Tacrine Acridine Derivative of Huperzine Organochlorine
Hup-19 ACHE BCHE Derivative of Huperzine Organochlorine
H34 ACHE BCHE Derivative of Huperzine Triazol Organochlorine
ZT-1 ACHE BCHE Derivative of Huperzine Organochlorine
2-Methoxyhuprine ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Natural_modified
HuprineY Derivative of Huperzine Organochlorine
HuperzineA ACHE Derivative of Huperzine Natural Alkaloid
HuperzineB ACHE Derivative of Huperzine Natural Alkaloid
HuprineW ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Organochlorine Natural_modified
HuprineX ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Natural_modified
IsovanihuperzineA ACHE Derivative of Huperzine
(R)-Tacrine(10)-Hupyridone ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Alkyl linked bis-ligand
(S,S)-(-)-bis(12)-hupyridone ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand
(S,S)-(-)-bis(10)-hupyridone ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand
Hupyridone ACHE Derivative of Huperzine Quinoline
Levetiracetam-huprine-hybrid-Cpd10 ACHE BCHE Pyrrolidine Multitarget Derivative of Huperzine Alkyl linked bis-ligand
Huptremule-D ACHE Octahydroazulenofuran Derivative of Huperzine Natural Alkaloid
Huptremule-C ACHE Octahydroazulenofuran Alkaloid Natural Derivative of Huperzine
Huptremule-A ACHE Alkaloid Natural Derivative of Huperzine
Lycocasuarine-C ACHE Derivative of Huperzine Natural Alkaloid
Lycocasuarinine-D ACHE Derivative of Huperzine Natural Alkaloid
N-demethylhuperzinine BCHE ACHE Derivative of Huperzine Natural Alkaloid
3,5-dihydroxybenzamido-huprine-hybrid-11 BCHE ACHE Multitarget Derivative of Huperzine BACE1-inhibitor Alkyl linked bis-ligand Organochlorine
K-1234 ACHE Derivative of Huperzine Derivative of Tacrine Acridine
8U2-7AIX7AY-compound5i ACHE BCHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Triazol Organochlorine
8U5-7AIW-compound5g ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UE-7AIV-compound5f ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UQ-7AIU-compound5d ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UK-7AIT-compound5c ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UH-7AIS-compound5b ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
E1N ACHE Derivative of Tacrine Acridine Derivative of Huperzine Organochlorine
Hup-19 ACHE BCHE Derivative of Huperzine Organochlorine
H34 ACHE BCHE Derivative of Huperzine Triazol Organochlorine
ZT-1 ACHE BCHE Derivative of Huperzine Organochlorine
2-Methoxyhuprine ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Natural_modified
HuprineY Derivative of Huperzine Organochlorine
HuperzineA ACHE Derivative of Huperzine Natural Alkaloid
HuperzineB ACHE Derivative of Huperzine Natural Alkaloid
HuprineW ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Organochlorine Natural_modified
HuprineX ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Natural_modified
IsovanihuperzineA ACHE Derivative of Huperzine
(R)-Tacrine(10)-Hupyridone ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Alkyl linked bis-ligand
(S,S)-(-)-bis(12)-hupyridone ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand
(S,S)-(-)-bis(10)-hupyridone ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand
Hupyridone ACHE Derivative of Huperzine Quinoline
Levetiracetam-huprine-hybrid-Cpd10 ACHE BCHE Pyrrolidine Multitarget Derivative of Huperzine Alkyl linked bis-ligand
Huptremule-D ACHE Octahydroazulenofuran Derivative of Huperzine Natural Alkaloid
Huptremule-C ACHE Octahydroazulenofuran Alkaloid Natural Derivative of Huperzine
Huptremule-A ACHE Alkaloid Natural Derivative of Huperzine
Lycocasuarine-C ACHE Derivative of Huperzine Natural Alkaloid
Lycocasuarinine-D ACHE Derivative of Huperzine Natural Alkaloid
N-demethylhuperzinine BCHE ACHE Derivative of Huperzine Natural Alkaloid
3,5-dihydroxybenzamido-huprine-hybrid-11 BCHE ACHE Multitarget Derivative of Huperzine BACE1-inhibitor Alkyl linked bis-ligand Organochlorine
K-1234 ACHE Derivative of Huperzine Derivative of Tacrine Acridine
8U2-7AIX7AY-compound5i ACHE BCHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Triazol Organochlorine
8U5-7AIW-compound5g ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UE-7AIV-compound5f ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UQ-7AIU-compound5d ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UK-7AIT-compound5c ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
8UH-7AIS-compound5b ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand Multitarget Derivative of Capsaicin Antioxidant Organochlorine
E1N ACHE Derivative of Tacrine Acridine Derivative of Huperzine Organochlorine
Hup-19 ACHE BCHE Derivative of Huperzine Organochlorine
H34 ACHE BCHE Derivative of Huperzine Triazol Organochlorine
ZT-1 ACHE BCHE Derivative of Huperzine Organochlorine
2-Methoxyhuprine ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Natural_modified
HuprineY Derivative of Huperzine Organochlorine
HuperzineA ACHE Derivative of Huperzine Natural Alkaloid
HuperzineB ACHE Derivative of Huperzine Natural Alkaloid
HuprineW ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Organochlorine Natural_modified
HuprineX ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Natural_modified
IsovanihuperzineA ACHE Derivative of Huperzine
(R)-Tacrine(10)-Hupyridone ACHE Derivative of Huperzine Derivative of Tacrine Quinoline Alkyl linked bis-ligand
(S,S)-(-)-bis(12)-hupyridone ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand
(S,S)-(-)-bis(10)-hupyridone ACHE Derivative of Huperzine Quinoline Alkyl linked bis-ligand
Hupyridone ACHE Derivative of Huperzine Quinoline